A5040285884- Renal function and acid-base balance
- Renal and Vascular Pathologies
- Ion Transport and Channel Regulation
- Renal Transplantation Outcomes and Treatments
- Dialysis and Renal Disease Management
- Diet and metabolism studies
- Neurological Complications and Syndromes
- Adrenal and Paraganglionic Tumors
- Electrolyte and hormonal disorders
- Organ Donation and Transplantation
- Pituitary Gland Disorders and Treatments
- Enzyme function and inhibition
- Poisoning and overdose treatments
- Pediatric Urology and Nephrology Studies
- Drug Transport and Resistance Mechanisms
- Myasthenia Gravis and Thymoma
- Pregnancy and Medication Impact
- Reproductive System and Pregnancy
- Chronic Kidney Disease and Diabetes
- Pregnancy and preeclampsia studies
- Patient Safety and Medication Errors
- Organ Transplantation Techniques and Outcomes
- Medical Malpractice and Liability Issues
- Clinical practice guidelines implementation
- Vitamin K Research Studies
Ospedale Santa Maria della Misericordia di Udine
2004-2022
University of Udine
2002-2021
Background. Intrarenal resistive index (RI) ≥ 0.80 predicts renal outcomes in proteinuric chronic kidney disease (CKD). However, this evidence non-proteinuric patients with CKD of unknown etiology is lacking. In study, we assessed the effect intrarenal RI on function and all-cause mortality despite an extensive diagnostic work-up. Methods. Non-proteinuric were evaluated a retrospective longitudinal study. Progression was investigated by checking serum creatinine levels at 1, 3, 5 years...
In chemistry and in acid-base physiology, the Henderson-Hasselbalch equation plays a pivotal role studying behaviour of buffer solutions. However, it seems that general function to calculate valence acids, bases ampholytes, N = f(pH), at any pH, has only been provided by Kildeberg. This can be applied strong acids bases, pluriprotic weak with an arbitrary number acid strength constants, pKA, including water. By differentiating this respect we obtain for value. addition, integrating titration...
Titratable Acidity (TA) in urine can be measured directly or calculated from actual and reference pH, by using the pKa2 6,8 for phosphate. In urine, H2PO4− represents excretion of filtered H2PO4−, filtrated HPO42− being completely reabsorbed proximal tubule (the Van Slyke approach). Since frequently exceeds its glomerular filtration, this approach is considered inadequate Pitts. He claimed that it tubular H+ secretion which converts to thereafter excreted urine. This only true under...
Acid generation and elimination processes compared to titratable non-metabolizable base (NaOH equivalents, NB) turnover in end-stage renal disease patients are examined the light of Law electroneutrality. The application over 2 days whole-body NB balance technique 18 undergoing continuous ambulatory peritoneal dialysis is evaluated. results show that mean rate loss with effluent (as bicarbonate organic acid anions) exceeded gain fluid salts lactic acid) by 24 (27), m (SD), mmol per days. In...
Acid generation and elimination processes were compared with total base (bicarbonate plus metabolizable anions) turnover in 18 anuric patients undergoing post-dilutional haemofiltration. The study was conducted during the second haemodialysis session of week by means a whole-body balance technique. results showed that mean rates loss gain dialysis did not differ (i.e. approximated to zero). concurrent rate intestinal absorption 66+/-26 mmol/2 days, as calculated from various inorganic cation...
Pregnancy can be considered as an allogeneic transplant and preeclampsia seen a failure of the acceptance mechanisms this occurs in acute organ rejection. Some genetic polymorphisms may involved its pathogenesis. Since kidney is one organs mainly preeclampsia, our study attempted to determine frequencies single nucleotide DNA (SNP) 3 genes (adenosine triphosphate-binding cassette sub-family B member 1 (ABCB1)/multi drug reactivity (MDR1) gene, interleukin 10 gene tumor necrosis factor α...
Searchable abstracts of presentations at key conferences in endocrinology ISSN 1470-3947 (print) | 1479-6848 (online)
The approach to acid-base chemistry in medicine includes several methods. Currently, the two most popular procedures are derived from Stewart's studies and bicarbonate/BE-based classical formulation. Another method, unfortunately little known, follows Kildeberg theory applied titration. By using data produced by Dana Atchley 1933, regarding electrolytes blood gas analysis diabetes, we compared three aforementioned methods, order highlight their strengths weaknesses. results obtained,...
The current emphasis on kinetics and in situ control of molecular exchanges, across the tubular membrane, has not been paralleled by corresponding improvements our understanding behaviour at macroscopic level classical physiology. In this paper, we propose a mathematical rationalization transport means principal equation, originating from law mass action between substrate carrier. other equations, derived main one, demonstrate possibility distinguishing transporters with low affinity high...
According to usual literature, the diet-dependent endogenous production of titratable acidity (TA) is contributed by sulphuric and phosphoric acids (NA) metabolizable (MAs), representing 'net-endogenous acid production' (NEAP). NEAP mainly neutralised [Formula: see text] salts inorganic cations ([Formula: text]), estimated in foods, faeces urine from cation-anion difference (NB). It claimed that urinary loss organic acids' anions, '[Formula: text]', induces H+ ions' retention. Since text]'...