Jianhuai Chen

ORCID: 0000-0003-0389-4049
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About
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Research Areas
  • Sexual function and dysfunction studies
  • Functional Brain Connectivity Studies
  • Advanced Neuroimaging Techniques and Applications
  • Urinary Bladder and Prostate Research
  • Evolutionary Psychology and Human Behavior
  • Hormonal and reproductive studies
  • Advanced MRI Techniques and Applications
  • Sexuality, Behavior, and Technology
  • Mental Health Research Topics
  • Healthcare and Venom Research
  • Pelvic floor disorders treatments
  • Tryptophan and brain disorders
  • Stress Responses and Cortisol
  • Neuroendocrine regulation and behavior
  • Eating Disorders and Behaviors
  • Personality Disorders and Psychopathology
  • Sexual Differentiation and Disorders
  • Acupuncture Treatment Research Studies
  • Cardiac tumors and thrombi
  • Optical Imaging and Spectroscopy Techniques
  • Diet and metabolism studies
  • Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
  • Treatment of Major Depression
  • Advanced X-ray and CT Imaging
  • Genital Health and Disease

Emory University
2025

Georgia Institute of Technology
2025

Nanjing University of Chinese Medicine
2015-2024

Jiangsu Province Hospital
2015-2024

Nanjing Drum Tower Hospital
2016-2023

Nanjing Medical University
2014-2022

Jiangsu Provincial Hospital of Traditional Chinese Medicine
2021

Jiangsu Provincial Academy of Traditional Chinese Medicine
2020

Nanjing Brain Hospital
2014-2016

China Academy of Chinese Medical Sciences
2015

Abstract Erectile Dysfunction (ED) is considered a physical and mental illness. A variety of potential associations between gut microbiota health or disease have been found. By comparing the healthy controls ED patients, our study investigated relationship microbiota. The results revealed that group exhibited significantly higher relative abundance Bacteroides , Fusobacterium Lachnoclostridium Escherichia‐Shigella Megamonas while showing lower Bifidobacterium compared to control group....

10.1111/1751-7915.14403 article EN cc-by-nc-nd Microbial Biotechnology 2024-01-01

Chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) is a chronic disease with variety of psychosocial and somatic symptoms. CP/CPPS has substantial health care costs unclear etiology, which may be caused by factors. Moreover, previous studies suggested that cognitive processes played crucial role in the perception pain. Therefore, aim this meta-analysis was to analyze characteristics men CP/CPPS, especially symptom catastrophizing.Relevant publications were searched different...

10.21037/tau.2020.01.25 article EN Translational Andrology and Urology 2020-04-01

Introduction Nonobstructive azoospermia (NOA) is a common and severe form of male infertility. Microdissection testicular sperm extraction (microTESE) combined with intracytoplasmic injection (ICSI) an optimal treatment for men NOA. However, the outcomes affecting factors ICSI NOA patients different etiologies receiving microTESE are still unclear. Methods A total 335 undergoing from January 2017 to December 2021 were included in this retrospective analysis. The divided into five groups...

10.3389/fendo.2022.1006208 article EN cc-by Frontiers in Endocrinology 2022-10-17

Abstract Background Few studies have investigated psychogenic sexual dysfunction including erectile (pED); the effect of tadalafil on behavior male rats induced by chronic unpredictable mild stress (CUMS) remains unclear. Aim The aim was to explore influence CUMS and effects that. Methods Adult were divided into 3 groups, normal group without CUMS, model with 6 weeks’ treatment during CUMS. consists water deprivation, food stroboscopic lightning, white noise, cage tilting, weeding packing,...

10.1093/sexmed/qfad019 article EN cc-by Sexual Medicine 2023-03-01

Various neuroimaging studies had identified changes of cerebral activity and structures during the processes sexual arousal. The brain regions were also believed to regulate emotional cognitive processes. Yet, little was known about neural mechanisms underlying psychogenic erectile dysfunction. Moreover, mediating processing arousal by these psychological unclear. To investigate this issue, graph theory applied evaluate topological properties functional networks among 24 dysfunction patients...

10.1111/andr.12411 article EN Andrology 2017-10-26

Premature ejaculation (PE), a common male sexual dysfunction, often accompanies by abnormal psychological factors, such as depression. Recent neuroimaging studies have revealed structural and functional brain abnormalities in PE patients. However, there is limited neurological evidence supporting the comorbidity of This study aimed to explore topological changes networks patients with

10.1002/brb3.3585 article EN cc-by Brain and Behavior 2024-06-01

Despite increasing understanding of the cerebral functional changes and structural abnormalities in erectile dysfunction, alterations topological organization brain networks underlying psychogenic dysfunction remain unclear.Here, based on diffusion tensor image data 25 patients 26 healthy controls, we investigated its correlations with clinical variables using graph theoretical analysis.Patients displayed a preserved overall small-world exhibited less connectivity strength left inferior...

10.1080/00207454.2017.1387116 article EN International Journal of Neuroscience 2017-10-03

Abstract Introduction Hyperactivity of the sympathetic nervous system was considered as one factors involved in pathological mechanisms premature ejaculation ( PE ). Sympathetic skin response penis PSSR ) used to evaluate activity innervations penis, which controlled by central (brain). Shorter found patients; however, little known regarding neural patients with high activity. Methods evaluated, and diffusion tensor images participants were collected. Graph theoretical analysis employed...

10.1111/andr.12701 article EN Andrology 2019-09-18

Chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) is characterized by chronic in area and lower urinary tract symptoms (LUTS). Previous neuroimaging studies demonstrated that was associated with the altered brain activity. However, pathological mechanisms control of CP/CPPS are not well-understood. Therefore, we sought to investigate topological properties white matter networks patients whether configuration frontal-parietal network disrupted. We collected 19 32 matched healthy...

10.1111/ejn.14962 article EN European Journal of Neuroscience 2020-09-28

Abstract Introduction Human brain was a complex network of interconnected regions. Recent neuroimaging studies had showed that the disruption connectivity associated with psychological disorders. Abnormal rich club and robustness networks might have key role in pathophysiology psychogenic erectile dysfunction ( pED ). Methods Both diffusion functional magnetic resonance imaging were performed patients healthy controls HC Measures organization under targeted attack explored. Results...

10.1111/andr.12684 article EN Andrology 2019-08-29

Nonorganic erectile dysfunction is a problem with unknown central mechanisms. Changes in brain activity the amygdala have been observed human patients. This study aimed to investigate dopamine system basolateral of male rats nonorganic dysfunction. We applied chronic mild stress induce After exposure stress, sucrose consumption test, sexual behaviour test and apomorphine were used select depression-like as model rats. The these after infusion D1/D2 receptor agonist/antagonist was observed....

10.1111/and.13160 article EN Andrologia 2018-10-01

Abstract Adipose tissue-derived stem cells (ADSCs) have been shown to improve erectile function in animal models of dysfunction. However, few studies carried out using a reliable vivo imaging method trace transplanted real time, which is necessary for systematic investigation cell therapy. The study aims explore the feasibility non-invasively monitoring intracavernous injection ADSCs rat and miniature pig corpus cavernosum magnetic resonance (MR) imaging. Thirty-six male Sprague Dawley rats...

10.1038/s41598-023-51076-2 article EN cc-by Scientific Reports 2024-01-22

The effectiveness of Tuina therapy has been confirmed in treating pain patients with cervical spondylosis (CS), however, its therapeutic mechanism is still unclear. This study aimed to observe the changes regional brain activity following painful CS based on resting-state functional magnetic resonance imaging (rs-fMRI) data.

10.3389/fneur.2024.1399487 article EN cc-by Frontiers in Neurology 2024-09-13

Abstract Introduction Recent neuroimaging studies have indicated that some brain areas are involved in the sexual behavior process. Pre‐mature ejaculation patients exhibit altered activation and abnormal cortical structures. However, there has been no research evaluating topological organization of structural network anejaculation ( AE ). Methods We employed diffusion tensor imaging data graph theory to examine whole‐brain networks among 16 23 healthy controls. In addition, results function...

10.1111/andr.12715 article EN Andrology 2019-10-14
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