A5045834516- Pregnancy and preeclampsia studies
- Reproductive System and Pregnancy
- Cardiovascular Issues in Pregnancy
- Birth, Development, and Health
- Nitric Oxide and Endothelin Effects
- Preterm Birth and Chorioamnionitis
- Epigenetics and DNA Methylation
- Prenatal Screening and Diagnostics
- Pregnancy-related medical research
- Traditional Chinese Medicine Studies
- Pancreatitis Pathology and Treatment
- S100 Proteins and Annexins
- Medicinal Plant Pharmacodynamics Research
- Pediatric Hepatobiliary Diseases and Treatments
- Cardiac Ischemia and Reperfusion
- Fatty Acid Research and Health
- Genetic Syndromes and Imprinting
- Appendicitis Diagnosis and Management
- Maternal and fetal healthcare
- Ectopic Pregnancy Diagnosis and Management
Affiliated Hospital of Southwest Medical University
2017-2024
First Affiliated Hospital of Sichuan Medical University
2008-2011
Southwest Medical University
2008-2011
Huashan Hospital
2009
Fudan University
2009
Cesarean scar pregnancy (CSP) is a rare but life-threatening type of ectopic pregnancy. This study's aim to investigate the clinical characteristics and possible risk factors for cesarean pregnancy.A clinically randomized, unpaired retrospective case-control study was implemented. A group 291 CSP patients control 317 full-term pregnant women with history section (CS) were recruited in our hospital from May 2013 October 2018. Their demographic medical obstetric collected.Only symptoms...
Pre-eclampsia is associated with altered maternal and placental vascular reactivity. Kv7 channels (encoded by KCNQ 1–5 genes) are a potential contributor to the regulation of tone in CPAs (chorionic plate arteries) during normal pregnancy. The aim this study establish expression profile subunits taken from women preeclampsia or normotensive examine functional relevance on an subunits. effects channel modulators were investigated tension measurement. Quantitative PCR experiments used analyze...
Abstract The objective of this study is to investigate the expression and influence adenosine triphosphate-sensitive potassium channel (KATP) in human umbilical arterial smooth muscle cells (HUASMCs) patients with hypertensive disorders pregnancy (HDP). Western blotting was used detect protein levels KATP inwardly rectifying (Kir)6.1 sulphonylurea receptor (SUR)2B subunits HUASMCs from normal parturients (NP), gestational hypertension (GH), chronic (CH), preeclampsia (PE) superimposed...
Abstract The aim of this study is to establish the expression ATP-sensitive potassium channels(KATP) in human umbilical arteries with severe pre-eclampsia. Real-time quantitative PCR and western blotting were used detect mRNA protein levels KATP channel subunits Kir6.1 SUR2B from normal pregnant those pre-eclampsia, early onset pre-eclampsia late group lower than ( P < 0.001), was not statistically significant between two groups > 0.05). 0.001). There no difference women women,...
Objective To investigate the potential mechanism of transient receptor vanilloid type 1 (TRPV1) and ATP-sensitive potassium channel (KATP) in severe preeclampsia. Design Basic research. Setting The pathogenesis Samples Human placental arterioles HUVECs. Methods (1) Tissue level: samples were divided into normotensive pregnancy (NP) group preeclampsia (SP) group. Hematoxylin-eosin staining, quantitative PCR, Western blotting immunohistochemistry performed. (2) Cellular control group, TRPV1...
The detection of foetal DNA and extravillus trophoblasts (EVTs) in early pregnancy cervical uterine samples offers a potential pathway for non-invasive prenatal diagnostics. However, the challenge lies effectively quantifying these samples. This study introduces novel approach using Ras association domain family 1 A (RASSF1A), which exhibits hypermethylation cells hypomethylation maternal cells. differential methylation pattern RASSF1A provides unique biomarker intrauterine
Background: To analyze the impact of a multidisciplinary collaborative diagnosis and treatment (MDT) management in obstetric outpatient departments on outcome high-risk pregnancies, to summarize experience improve ability for critically ill patients. Method: Two hundred sixty-six pregnant lying-in women with were selected retrospective analysis. According criteria, 176 included, including 83 cases MDT 93 inpatient MDT. The classification pregnancy diseases risk was carried out. source women,...
Severe preeclampsia is one of the most serious obstetric diseases. However, pathogenesis disease not fully understood. In present study, placental artery and blood serum was collected from patients with severe preeclampsia, as well normal pregnant women. The results reverse transcription-quantitative (q)PCR, western blotting, immunohistochemical staining revealed markedly decreased transient receptor potential cation channel subfamily V member 1 (TRPV1), ATP-sensitive potassium (KATP)...