A5070438583- Ubiquitin and proteasome pathways
- Peptidase Inhibition and Analysis
- Multicomponent Synthesis of Heterocycles
- Endoplasmic Reticulum Stress and Disease
- Synthesis and Biological Evaluation
- Oxidative Organic Chemistry Reactions
- Software Testing and Debugging Techniques
- Metal-Catalyzed Oxygenation Mechanisms
- Software Engineering Research
- Polysaccharides and Plant Cell Walls
- Plant tissue culture and regeneration
- Gut microbiota and health
- Remote Sensing in Agriculture
- Ginseng Biological Effects and Applications
- Synthesis and biological activity
- Spectroscopy and Chemometric Analyses
- Software System Performance and Reliability
- Catalytic C–H Functionalization Methods
- Protein Degradation and Inhibitors
- Clostridium difficile and Clostridium perfringens research
- Cancer, Hypoxia, and Metabolism
- Phagocytosis and Immune Regulation
- Pharmacological Effects of Natural Compounds
- Morinda citrifolia extract uses
- Phytochemistry and biological activity of medicinal plants
Nanjing Normal University
2021-2024
Henan Agricultural University
2023-2024
Sun Yat-sen University
2023-2024
Chongqing University
2023
Hebei Normal University
2021-2022
Ji Hua Laboratory
2021
Wuhan University of Technology
2021
Hubei University of Automotive Technology
2021
Wenzhou Medical University
2020
Tianjin University of Science and Technology
2009-2010
Crop disease identification and monitoring is an important research topic in smart agriculture. In particular, it a prerequisite for detection the mapping of infected areas. Wheat fusarium head blight (FHB) serious threat to quality yield wheat, so rapid wheat FHB important. This study proposed method based on unmanned aerial vehicle (UAV) low-altitude remote sensing multispectral imaging technology combined with spectral textural analysis monitor FHB. First, imagery population was collected...
Fault localization (FL) analyzes the execution information of a test suite to pinpoint root cause failure. The class imbalance suite, i.e., imbalanced proportion between passing cases (i.e., majority class) and failing ones minority class), adversely affects FL effectiveness.To mitigate effect in FL, we propose CGAN4FL: data augmentation approach using Context-aware Generative Adversarial Network for Localization. Specifically, CGAN4FL uses program dependencies construct failure-inducing...
Peanut southern blight is a soil-borne fungal disease caused by Agroathelia rolfsii (syn. Sclerotium rolfsii) Sacc, which seriously affects peanut yield. The mainly the stem, pod, and root of plant, it difficult to detect visual interpretation. Detecting using existing technology an urgent problem that needs be solved. To address this issue, field experiments were conducted in September 2022 determine whether hyperspectral techniques could used assess severity blight. In study, we obtained...
Fe 3 O 4 @SiO 2 ‐CeCl catalyzed chemoselective synthesis of functionalized 3‐substituted‐1,5‐benzodiazepines via one‐pot multicomponent and domino reactions has been developed. During the process, one new cycle four bonds (one C–C, two C–N C=C) were constructed by nucleophilic addition eliminate reaction (dehydration etc.) intramolecular proton transfer cyclization process. The major advantages present method are good to excellent yields, shorter time, simple experimental procedure, easy...
Triple‐negative breast cancer (TNBC) is an aggressive subtype, which has poor prognosis due to the lack of effective targeted drugs. KPT‐330, inhibitor nuclear export protein CRM‐1, been widely used in clinical medicine. Y219, a novel proteasome designed by our group, shows superior efficacy, reduced toxicity, and off‐target effects as compared bortezomib. In this study, we investigated synergistic effect KPT‐330 Y219 against TNBC cells, well underlying mechanisms. We report that combination...
The driver’s attentional state is a significant human factor in traffic safety. executive control process crucial sub-function of attention. To explore the relationship between driving performance and function, total 35 healthy subjects were invited to take part simulated experiment task-cuing experiment. divided into three groups according their (aberrant behaviors, including lapses errors) by clustering method. Then efficiency electroencephalogram (EEG) data acquired compared among groups....
FHND6091, a novel N-capped dipeptidyl boronic acid proteasome inhibitor with promising pharmacological properties, entirely converted into active form FHND6081 under physiological conditions. The proteasome, key component of the ubiquitin-proteasome pathway (UPP), has emerged as validated target multiple myeloma (MM) therapeutics. FHND6091 is selective oral that binds irreversibly to β5 submit 20S and exerts anti-cancer roles. In this study, we investigated metabolic stability, metabolite...
1,5-Benzodiazepine compounds are seven-membered nitrogen heterocyclic with important biological and pharmacological activities.Ester group, carboxyl acyl group aryl active groups of 1,5-benzodiazepine compounds.One-pot green synthesis 34 kinds 1,5-benzodiazepines COR, COOR or COOH by three-component tandem reaction was performed at room temperature (25 ℃) a yield up to 90%.The mechanism catalytic proposed.These reactions were achieved using aldehyde carbonyl dicarbonyl compounds,...
Pest management technology has been a promising bioconversion method for waste resource utilization. Unlike many pests that consume waste, maggots have outstanding advantages as following: with their strong adaption to environment and not easily infected, exhibit medicinal nutritional value. Efficient feasible utilization of productivity process is significant both economical environmental reasons. Herein, the potential efficacies maggot polysaccharides (MP), well underlying mechanisms, were...
Regulating the selective generation of reactive oxygen species (ROS) is a significant challenge in field photocatalytic oxidation, with successful approaches still being limited. Herein, we present strategy to selectively generate singlet (