A5101643713- Phytochemicals and Antioxidant Activities
- Proteins in Food Systems
- Protein Hydrolysis and Bioactive Peptides
- Natural product bioactivities and synthesis
- Nanocomposite Films for Food Packaging
- Meat and Animal Product Quality
- Genomics, phytochemicals, and oxidative stress
- Tea Polyphenols and Effects
- Atherosclerosis and Cardiovascular Diseases
- Immune Cell Function and Interaction
- Cancer-related Molecular Pathways
- Gut microbiota and health
- Phytase and its Applications
- Chemotherapy-induced organ toxicity mitigation
- Occupational and environmental lung diseases
- Plant Molecular Biology Research
- Horticultural and Viticultural Research
- Postharvest Quality and Shelf Life Management
- Hematopoietic Stem Cell Transplantation
- Plant Gene Expression Analysis
- Bacterial Identification and Susceptibility Testing
- Plant biochemistry and biosynthesis
- T-cell and B-cell Immunology
- Eicosanoids and Hypertension Pharmacology
- Connective Tissue Growth Factor Research
Zhejiang University of Technology
2020-2024
Sichuan University
2024
West China Hospital of Sichuan University
2024
Tibet University
2011-2024
Anhui Medical University
2023
Zhejiang Sci-Tech University
2023
Shaoxing University
2023
University of Tennessee at Knoxville
2019-2022
Southwest Forestry University
2022
Shenyang Agricultural University
2012-2021
Significance MicroRNAs (miRNAs) are indispensable regulators of gene expression. Hyponastic Leaves 1 (HYL1) is a core component the microprocessor that processes primary miRNAs (pri-miRNAs) into mature miRNAs. Here we report noncanonical function HYL1 in protecting pri-miRNAs from unwanted nuclear exosome activities during processing. Our observations also suggest may contribute differently to Dicer-like (DCL1)-mediated maturation loop-to-base– and base-to-loop–processed pri-miRNAs. This...
Abstract Natural compounds have been increasingly investigated as substances enhancing the effect of drugs and reducing drug‐related adverse reactions. The objective this study was to determine how a combination cisplatin (DDP) with cyanidin‐3‐ O ‐glucoside (C3G) affected malignancy features cervical cancer cells. results demonstrated that proliferation HeLa cells treated 5 µg/ml DDP, 400 C3G, or both (5 DDP C3G) inhibited by 17.43%, 34.98%, 63.38%, respectively. IC 50 values for DDP/C3G...
High-fat diet (HFD) induces imbalance in the small intestine environment, where fat digestion and absorption mainly take place. This study aimed to elucidate mechanisms by which Lonicera caerulea polyphenols (LCP) might inhibit absorption, from perspective of microbiota epithelial barrier integrity. Male Sprague-Dawley rats were given HFD with or without co-administration LCP for 8 weeks. The results showed that supplementation significantly decreased levels serum triglycerides (TG), total...
Sterility testing of hematopoietic stem cells (HSCs) at The Canadian Blood Services Stem Cell Laboratory is performed using BacT/ALERT aerobic (SA) culture bottles. This study was conducted to verify the efficacy this method and assess use (BPA) anaerobic (BPN) bottles for microbial HSCs.HSC products, including cryopreserved apheresis peripheral blood, marrow, cord blood fresh were spiked with four organisms Staphylococcus epidermidis, Bacillus cereus, Pseudomonas aeruginosa, Candida...
Background Amantadine is currently recommended for use in patients of post-traumatic brain injury with unresponsive wakefulness syndrome (UWS). However, the application amantadine UWS after cerebral hemorrhage has only been rarely reported. This allows a further exploration role treatment resulting from severe hemorrhage.Methods We observed changes seven intracerebral taking amantadine. also carried out detailed neurological examination patient disorders consciousness to include or exclude...
Fennel essential oil was encapsulated in β-cyclodextrin to prepare microcapsules (β-CD-FEO). Single-factor experiments and model fitting were used optimise the microcapsules. When optimal core/wall material ratio 10:0.6, encapsulation time set as 90 min, temperature controlled at 60°C, an efficiency of 77.05 ± 0.14% can be obtained. Using β-CD-FEO blended with low acyl gellan gum (LA-GG) main constituents, three-component coating solutions containing sodium alginate (SA), carboxymethyl...
Abstract The use of natural compounds to potentiate the effect drugs and lower their adverse effects is an active area research. objective determine combined blueberry extracts (BE) oxaliplatin (OX) in colon cancer cells. results demonstrated that treatments BE/OX showed inhibitory on HCT‐116 cell nontoxic CCD‐18Co normal Flow cytometry analysis indicated treatment with BE, OX or combination could induce G0/G1 cycle arrest, apoptosis, increase reactive oxygen species, loss mitochondrial...
The anthocyanins extracted from Aronia melanocarpa are of great interest because their potential health-related functionalities. However, poor stabilities have limited use in applications. Hence, to improve physical and oxidative stability, we optimised the chitosan nanocapsules encapsulating melanocarpa, evaluated systems terms physicochemical characteristics, oxidant stability simulated gastrointestinal digestion different storage environments. Results show that obtained present favorable...
Investigation on potentiation of existing drugs with natural compounds to enhance efficacy and reduce toxic effect the has been increasing in recent years. This paper reports cytotoxic (apoptosis-related oxidative stress-related effect) cyanidin-3-O-glucoside (C3G), cisplatin (DDP), their combination (C3G-DDP) cervical cancer HeLa cells. Concentration intracellular reactive oxygen species (ROS) was determined by employing fluorescent marker 2',7'-dichlorodihydrofluorescein diacetate. On...