A5051249528- Phytochemicals and Antioxidant Activities
- Food Quality and Safety Studies
- Fermentation and Sensory Analysis
- Postharvest Quality and Shelf Life Management
- Pesticide Residue Analysis and Safety
- Microbial Inactivation Methods
- Phytochemical and Pharmacological Studies
- Horticultural and Viticultural Research
- Ginseng Biological Effects and Applications
- Synthesis and Biological Evaluation
- Chemotherapy-induced organ toxicity mitigation
- Analytical chemistry methods development
- Plant Physiology and Cultivation Studies
- Natural product bioactivities and synthesis
- Ziziphus Jujuba Studies and Applications
- Pharmacological Effects and Assays
- Bioactive Compounds and Antitumor Agents
- Toxin Mechanisms and Immunotoxins
- Food Industry and Aquatic Biology
- Cell death mechanisms and regulation
- Listeria monocytogenes in Food Safety
- Bacillus and Francisella bacterial research
- Sulfur Compounds in Biology
- Protein Interaction Studies and Fluorescence Analysis
- GABA and Rice Research
Shenyang Agricultural University
2016-2025
Ministry of Agriculture and Rural Affairs
2022-2024
Protein lysine lactylation is a new post-translational modification (PTM) prevalently found in fungi and mammalian cells that directly stimulates gene transcription regulates the glycolytic flux. However, sites regulations remain largely unexplored, especially cereal crops. Herein, we report first global lactylome profile rice, which effectively identified 638 across 342 proteins rice grains. Functional annotations demonstrated was enriched associated with central carbon metabolism protein...
The proportion of foodborne disease caused by pathogenic microorganisms is rising worldwide, with staphylococcal food poisoning being one the main causes this increase. Juglone a plant-derived 1,4-naphthoquinone confirmed antibacterial and antitumor activities. However, specific mechanism underlying its activity against Staphylococcus aureus remains unclear. To elucidate activity, isobaric tags for relative absolute quantitation methods quantitative proteomics were applied analysis 53...
Aronia melanocarpa polyphenols (AMPs) can alleviate the degree of liver diseases in rats. However, mechanism by which this is achieved through gut microbiota modulation remains unclear. Here, a rich-polyphenol extract A. was used to treat lipopolysaccharide (LPS)-induced To gain insights into anti-LPS-induced disease, function index, expression apoptosis proteins, inflammatory factors, and activation signaling pathways were determined with western blot analysis, immunohistochemistry, 16S...
We investigated the cytoprotective effects of anthocyanins in Aronia melanocarpa against apoptosis induced by Aβ1-42, a key mediator AD pathophysiology. measured intracellular calcium with colorimetric kit, cellular DAPI, ROS fluorescent marker 2,3-dimethoxy-1,4-naphthoquinone, mitochondrial membrane potential JC-1, and ATP kit. Gene transcription protein expression levels calmodulin, cytochrome c, caspase-9, cleaved caspase-3, Bcl-2, Bax were analyzed RT-PCR Western blotting. The results...
Abstract Natural compounds have been increasingly investigated as substances enhancing the effect of drugs and reducing drug‐related adverse reactions. The objective this study was to determine how a combination cisplatin (DDP) with cyanidin‐3‐ O ‐glucoside (C3G) affected malignancy features cervical cancer cells. results demonstrated that proliferation HeLa cells treated 5 µg/ml DDP, 400 C3G, or both (5 DDP C3G) inhibited by 17.43%, 34.98%, 63.38%, respectively. IC 50 values for DDP/C3G...
To investigate the hypoglycemic components from acid hydrolyzates of Panax quinquefolius total saponins, and screen active compounds by in vitro inhibitory activities to α-glycosidase enzymes protein tyrosine phosphatase-1B (PTP1B).The were chromatographed repeatedly over silica gel column, structures determined means NMR. The bioassay was performed through effects on α-glucosidase or/and PTP1B.Eight isolated, which identified as 20(S)-panaxadiol (1),...
Juglone is a plant-derived 1,4-naphthoquinone with confirmed antibacterial activity. However, the mechanism of action juglone against Staphylococcus aureus remains unclear. Possible mechanisms were explored by proteomic analysis S. proteins that are inhibited juglone. Two-dimensional gel electrophoresis revealed 21 protein spots differentially expressed between juglone-treated and untreated cells which 13 identified. A bioinformatic participating in synthesis, tricarboxylic acid cycle, as...
Summary Apple pomace (APP) is the main by‐product in apple processing industry with abundant functional components. To improve APP economic value, superfine grinding (SG) was used as an effective method. The result showed that SG provided great uniformity and particle size of APP. Also, treatment, water‐holding capacity oil‐holding increased from 7.50 to 8.13 g −1 2.07 3.81 , respectively. Furthermore, enhanced sensory properties by increasing brightness, yellowness sweetness decreasing...
One new dammarane-type triterpene, gypsapogenin A (1), was isolated from the acid hydrolyzate of total saponins Gynostemma pentaphyllum (Thunb.) Makino, together with two known compounds, (20S,24S)-3β,20,21β,23β,25-pentahydroxy-21,24-cyclodammarane (2) and (23S)-3β-hydroxydammar-20,24-dien-21-oic 21,23-lactone (3). Its structural elucidations were accomplished mainly on basis interpretation spectroscopic data, such as IR, HR-TOF-MS, NMR. The cytotoxic activities evaluated against HepG2 A549...
Oil crops and products are important food materials in daily life. Pesticide residues could directly indirectly endanger human health. However, the method for detecting multiple pesticides simultaneously is limited. In this study, an easy efficient simultaneous determination of 38 oil was established validated.All samples were treated with a modified QuEChERS procedure followed by ultra-high-performance liquid chromatography/tandem mass spectrometry (UHPLC/MS/MS) analysis. Mass performed...
Sea buckthorn has strong physiological activities, which might be attributed to its flavonoid compounds. The heat treatment could speed up the transformation of flavonoids, so it would affect properties flavonoids. To explore effect heat-treating methods on sea pulp compositions, color and taste properties, antioxidant activity, prepared by three heating methods, were investigated. results showed that extractable flavonoids rose after treatment; high temperature with high-pressure had...
High hydrostatic pressure (HHP) is a widely accepted nonthermal technology for ensuring food safety without compromising nutritional values and organoleptic properties. This study investigated the survival molecular responses of Escherichia coli O157:H7 when it was subjected to HHP. The inactivation E. by HHP observed at 250 MPa higher pressures (p < 0.05), but not 50 150 MPa. Whole transcriptome sequencing (RNA-seq) revealed underlying adaptive induced slightly elevated pressure. Under HHP,...
Fermentation effects the flavor and properties of sea buckthorn. However, little literature has investigated composition buckthorn during lactic acid fermentation (LAF) alcoholic (yeast fermentation, YF). In this study, compositions pulp (SBP) fermented by lactobacilli yeast were compared based on widely targeted metabolomics for exploring correlations metabolic processes with property changes. After total flavonoid content increased, antioxidant capacity improved color varied significantly....