Zhaoxia Wu

ORCID: 0000-0001-6230-7452
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About
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Research Areas
  • Postharvest Quality and Shelf Life Management
  • Listeria monocytogenes in Food Safety
  • Phytochemicals and Antioxidant Activities
  • GABA and Rice Research
  • Meat and Animal Product Quality
  • Microbial Inactivation Methods
  • Metabolism, Diabetes, and Cancer
  • Adipose Tissue and Metabolism
  • Aquaculture Nutrition and Growth
  • Food composition and properties
  • Nanocomposite Films for Food Packaging
  • Bioactive Compounds and Antitumor Agents
  • Anesthesia and Pain Management
  • Aquaculture disease management and microbiota
  • Biochemical Analysis and Sensing Techniques
  • Ubiquitin and proteasome pathways
  • Toxin Mechanisms and Immunotoxins
  • Reproductive System and Pregnancy
  • Pesticide Residue Analysis and Safety
  • Advanced Chemical Sensor Technologies
  • Spectroscopy and Chemometric Analyses
  • Edible Oils Quality and Analysis
  • Anesthesia and Neurotoxicity Research
  • Cancer Risks and Factors
  • Bacterial biofilms and quorum sensing

Zhejiang University
2023-2025

Shenyang Agricultural University
2015-2024

Fudan University
2009-2024

Ministry of Agriculture and Rural Affairs
2024

Tongren Hospital
2021-2024

Shanghai Jiao Tong University
2011-2024

Minhang District Central Hospital
2017-2024

Guilin University of Electronic Technology
2023

Wuchang University of Technology
2023

Wuhan University of Science and Technology
2023

Luteolin, a polyphenolic flavone, has been demonstrated to exert anti-tumor activity in various cancer types. Cisplatin drug resistance is major obstacle the management of ovarian cancer. In present study, we investigated chemo-sensitizing effect luteolin both cisplatin-resistant cell line and mice xenotransplant model. vitro, CCK-8 assay showed that inhibited proliferation dose-dependent manner, enhanced anti-proliferation cisplatin on CAOV3/DDP cells. Flow cytometry revealed apoptosis...

10.1186/s13048-018-0468-y article EN cc-by Journal of Ovarian Research 2018-11-19

This study investigated the physicochemical and flavor quality changes in fresh-cut papaya that was stored at 4 °C. Multivariate statistical analysis used to evaluate freshness of papaya. Aerobic plate counts were selected as a predictor papaya, prediction model for established using partial least squares regression (PLSR), support vector machine (SVMR) algorithms. Freshness could be well distinguished based on analyses. The aerobic counts, significantly correlated with storage time. SVMR...

10.1016/j.heliyon.2024.e30255 article EN cc-by-nc-nd Heliyon 2024-04-26

The proportion of foodborne disease caused by pathogenic microorganisms is rising worldwide, with staphylococcal food poisoning being one the main causes this increase. Juglone a plant-derived 1,4-naphthoquinone confirmed antibacterial and antitumor activities. However, specific mechanism underlying its activity against Staphylococcus aureus remains unclear. To elucidate activity, isobaric tags for relative absolute quantitation methods quantitative proteomics were applied analysis 53...

10.3390/ijms17060965 article EN International Journal of Molecular Sciences 2016-06-18

Proanthocyanidins, including polymers with both low and high degrees of polymerization, are the focus intensive research worldwide due to their antioxidant activity, medicinal applications, pharmacological properties. However, nutritional value these compounds is limited because they readily form complexes proteins, polysaccharides, metal ions when consumed. In this study, we examined effects proanthocyanidins different polymerization on white mice. Twenty-four male mice were randomly...

10.3390/molecules23112916 article EN cc-by Molecules 2018-11-08

Lactic acid (LA) is an effective sanitizer for disinfection of fresh produce. Tap water generally used to wash disinfected produce because residues negatively affect the quality and organoleptic properties However, tap ineffective secondary compared with sanitizers. Thus, we propose a method using LA plus aqueous ozone (AO), oxidizing that does not lead residue. We proposed 1% (90 s) 1 mg L

10.1039/c9ra03544c article EN cc-by-nc RSC Advances 2019-01-01

Ascorbic acid (AsA) is a non-enzymatic antioxidant abundant in kiwifruit. However, physical injuries and long-term storage can decrease the AsA content shorten shelf-life of fresh-cut This study confirmed that treatment with 1 mg/L ozone for 10min was an effective fresh-keeping strategy, as indicated alleviating loss, promoting capacity inhibiting bacterial growth, thereby prolonging The results revealed ozonized kiwifruits exhibited higher by increasing glutathione (GSH) activities key...

10.1016/j.lwt.2022.114196 article EN cc-by-nc-nd LWT 2022-11-21

In minimal processing industry, chlorine is widely used in the disinfection process and ultrasound (US) increases efficacy of reduces cross-contamination incidence during washing. Tap water (TW), which has no effect, generally to rinse off sanitizer residues on surface disinfected fresh-cut vegetables. this study, aqueous ozone (AO), a low-cost residue-free sanitizer, was replace TW rinsing combination with US (28 kHz)–chlorine (free [FC] at 10 ppm, concentration recommended for industrial...

10.1016/j.ultsonch.2022.105931 article EN cc-by Ultrasonics Sonochemistry 2022-01-23

Fatty acids in edible oil will be oxidized into aldehydes and ketones during hot processing, which produce polycyclic aromatic hydrocarbons (PAHs) other harmful substances to human health. Hazelnut was heated under different temperatures times. For each type of sample, fatty acid composition, glyceride core aldehyde (GCAs), PAHs were investigated. The correlation between these indicators analyzed by the Pearson coefficient. As main component hazelnut oil, oleic plays an essential role...

10.15586/qas.v16i3.1441 article EN cc-by-nc-nd Quality Assurance and Safety of Crops & Foods 2024-08-07

Non-puerperal mastitis (NPM) is an inflammatory breast disease affecting women during non-lactation periods, and it prone to relapse after being cured. Accurate prediction of its recurrence crucial for personalized adjuvant therapy, pathological examination the primary basis classification, diagnosis, confirmation non-puerperal mastitis. Currently, there a lack models The aim this research create validate model using machine learning patients with We retrospectively collected laboratory data...

10.1371/journal.pone.0315406 article EN cc-by PLoS ONE 2025-01-16

Background Propolis, a natural mixture rich in bioactive compounds, has shown the potential to relieve exercise-induced fatigue. However, underlying mechanism remains unclear. This study aimed explore anti-fatigue effects of ethanol extract propolis (EEP) and its mechanisms. Methods Male C57BL/6 mice aged 6–8 weeks were subjected swim training with or without EEP supplementation (400 mg/kg.bw) for 3 weeks, followed by exhaustive swimming test simulate The exhaustion time fatigue-related...

10.3389/fnut.2025.1549913 article EN cc-by Frontiers in Nutrition 2025-03-26

Background and objective The treatment of impacted upper ureteral stones remains a significant challenge for urologists. Standard protocols often favor Mini-Percutaneous Nephrolithotripsy (Mini-PCNL). It has been supposed to be associated with higher stone clearance rate lower incidence stricture compared Flexible Ureteroscopy (FURS). Recently, FURS flexible navigable suction access sheath (FANS) emerged as promising alternative. aim this study was compare the efficacy safety FANS Mini-PCNL...

10.3389/fsurg.2025.1562428 article EN cc-by Frontiers in Surgery 2025-03-27

Abstract The von Hippel-Lindau (VHL) is deficient in ∼70% of clear-cell renal cell carcinomas (ccRCC), which contributes to the carcinogenesis and drug resistance ccRCC. Here we show that VHL-deficient ccRCC cells present enhanced cytotoxicity anthracyclines a hypoxia-inducible factor-independent manner. By subtractive proteomic analysis coupling with RNAi or overexpression verification, aldehyde dehydrogenase 2 (ALDH2) found be transcriptionally regulated by VHL cells. Furthermore,...

10.1038/ncomms15337 article EN cc-by Nature Communications 2017-06-15

The potent neurotoxic agent acrylamide (ACR) is formed during Maillard reaction in food processing. Epigallocatechin-3-gallate (EGCG), a major bioactive component of green tea, an antioxidant, but its effects on ACR-induced neurotoxicity are unclear. Here, we investigated the neuroprotective EGCG against apoptosis and astrogliosis cerebral cortex. Rats were pretreated with for 4 d then co-administered ACR 14 d. Immunohistochemical analysis glial fibrillary acidic protein...

10.1080/15376516.2017.1279251 article EN Toxicology Mechanisms and Methods 2017-01-05

Reduction of sanitizer dosage and development non-immersion disinfection methods have become major focuses research. Here, we examined the efficacy combining gaseous ozone (4 8 ppm) with aerosolized oxidizing [sodium hypochlorite (SH, 100 200 ppm)] organic acid [acetic (AA, 1% 2%) lactic (LA, 2%)]. Notably, AA 4 ppm were ineffective for disinfecting Salmonella Typhimurium, treatment + caused browning lettuce leaves stimulated increases in aerobic mesophilic count (AMC), psychrotrophic (APC),...

10.1016/j.ultsonch.2021.105622 article EN cc-by Ultrasonics Sonochemistry 2021-06-06

Ultrasound (US) has limited disinfection efficacy, and it been recommended to combine with chemical disinfectants during fresh produce washing. After washing before packaging, the effect of US-assisted can be weakened; thus, in-package is important. As a nutritious fruit, there are no packaged blueberries directly eaten. Therefore, in this study, blueberry was selected as model, two most commonly used (free chlorine [FC] at 10 ppm peracetic acid [PAA] 80 ppm) were combined low-frequency US...

10.1016/j.ultsonch.2022.105960 article EN cc-by Ultrasonics Sonochemistry 2022-02-25
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