A5019899355- Respiratory viral infections research
- Influenza Virus Research Studies
- Viral gastroenteritis research and epidemiology
- Physiological and biochemical adaptations
- Virus-based gene therapy research
- Air Quality and Health Impacts
- Animal Disease Management and Epidemiology
- Genomics and Phylogenetic Studies
- Identification and Quantification in Food
- Viral Infections and Vectors
- Occupational and environmental lung diseases
- Ocean Acidification Effects and Responses
- Streptococcal Infections and Treatments
- Marine Bivalve and Aquaculture Studies
- Flood Risk Assessment and Management
- Genetic diversity and population structure
- Environmental Toxicology and Ecotoxicology
- Insect-Plant Interactions and Control
- Neonatal and Maternal Infections
- Insect and Pesticide Research
- Occupational exposure and asthma
- Aquaculture Nutrition and Growth
- Fish Ecology and Management Studies
- Constructed Wetlands for Wastewater Treatment
- interferon and immune responses
China National Offshore Oil Corporation (China)
2021-2025
Sichuan University
2025
Children's Hospital of Chongqing Medical University
2023-2024
Chongqing Medical University
2023-2024
Tianjin Medical University Cancer Institute and Hospital
2024
Shanghai Ocean University
2012-2024
Hebei University of Technology
2023-2024
Nanchang University
2022-2023
Shenyang Agricultural University
2022-2023
Beijing Normal University
2023
Abstract Transcriptional plasticity is a major driver of phenotypic differences between species. The lower temperature limit (LTL), namely the end survival temperature, an important trait delimiting geographical distribution species, however, genetic mechanisms are poorly understood. We investigated inter-species transcriptional diversification in cold responses zebrafish Danio rerio and tilapia Oreochromis niloticus , which were reared at common (28 °C) but have distinct LTLs. identified...
Scarlet fever is one of a variety diseases caused by group A Streptococcus (GAS). During 2011, scarlet epidemic characterized peak monthly incidence rates 2.9-6.7 times higher than those in 2006-2010 occurred Beijing, China. the epidemic, hospital-based enhanced surveillance for and pharyngitis was conducted to determine characteristics circulating GAS strains. The identified 3,359 clinical cases or pharyngitis. isolated from 647 patients; 76.4% strains were type emm12, 17.1% emm1. Almost...
The transcriptional programs of ectothermic teleosts are directly influenced by water temperature. However, the cis- and trans-factors governing cold responses not well characterized. We profiled changes in eight zebrafish tissues exposed to mildly severely temperatures using RNA-Seq. A total 1943 differentially expressed genes (DEGs) were identified, from which 34 clusters representing distinct tissue temperature response expression patterns derived k-means fuzzy clustering algorithm....
Severe acute respiratory infection (SARI) threatens human health and even survival, causing a huge number of hospitalized patients every year. However, as one the most common viruses circulated worldwide, epidemiological phylogenetic characteristics parainfluenza virus (HPIV) in these cases were not well known.To reveal features HPIV SARIs Beijing area from September 2014 to August 2016.A total 1229 SARI enrolled, investigated, sampled, tested by multiplex real-time PCR identify HPIVs other...
Abstract Introduction Accumulating evidence demonstrates that aberrant methylation of enhancers is crucial in gene expression profiles across several cancers. However, the latent effect differently expressed between INSS stage 4S and 4 neuroblastoma (NB) remains elusive. Methods We utilized transcriptome data NB patients to perform Enhancer Linking by Methylation/Expression Relationships (ELMER) analysis, discovering a motif within 67 NB. Harnessing genes, we established related signature...
Timely and accurate oil well production warnings are crucial for optimizing oilfield management enhancing economic returns. Traditional methods predicting early warning systems face significant limitations in terms of adaptability accuracy. Artificial intelligence offers an effective solution to address these challenges. This study focuses on the ultra-high water cut stage water-driven medium-to-high permeability reservoirs, where cut—defined as ratio produced total fluid—exceeds 90%. At...
Plant growth-promoting rhizobacteria (PGPR) are beneficial bacteria residing in the rhizosphere and capable of enhancing plant growth through various mechanisms. Streptomyces sp. GD-4 is a bacterium isolated from soil Leymus secalinus. To further elucidate molecular mechanisms underlying effects strain on growth, we evaluated forage grasses conducted comprehensive genome mining comparative genomic analysis strain. Strain effectively colonized three forages significantly promoted both roots...
Nerve agents, a highly toxic class of chemical warfare pose serious risks to human health and social stability. Metal oxides are commonly used as catalysts break down these agents through thermocatalytic decomposition. In particular, bimetallic oxide offer enhanced stability catalytic efficiency due their synergistic effects. this study, CuO/ZrO2 composite with varying Cu/Zr ratios were synthesized using secondary hydrothermal method, resulting in hollow microsphere morphology. The...
Promoting the reactivity of surface lattice oxygen atoms oxide nanomaterials is critical for enhancing their catalytic performances in oxidation, hydrogenation, and electrocatalytic reactions; however, fundamental electronic mechanisms governing this have long remained insufficiently understood. Here, we reveal mechanism how nanoscale grain boundary (GB) boosts intrinsic CeO2 nanomaterials, which GBs are introduced by pyrolyzing precursors cerium carbonate formate. The results X-ray...
The rising anthropogenic atmospheric CO2 results in the reduction of seawater pH, namely ocean acidification (OA). In East China Sea, largest coastal hypoxic zone was observed world. This region is also strongly impacted by as receiving much nutrient from Changjiang and Qiantangjiang, organisms can experience great short-term natural variability DO pH this area. order to evaluate defense responses marine mussels under scenario, thick shell mussel Mytilus coruscus were exposed three pH/pCO2...
The continued spread of highly pathogenic avian influenza (HPAI) viruses H5 and H7 subtypes low (LPAI) H5, H9 in birds the subsequent infections humans pose an ongoing pandemic threat. It has been proposed that poultry workers are at higher risk exposure to HPAI or LPAI subsequently infection due their repeated chickens domestic waterfowl. aim this study was examine seroprevalence antibodies against amongst duck-related Beijing, China factors associated with seropositivity. In March, 2011,...
Background: Interferon Inducible Transmembrane 3 (IFITM3) is a key factor in interferon pathway and it involves host's immune response against multiple viruses. IFITM3 rs12252-C was associated with severe influenza virus infection several studies, however whether this association universal to all types of or diverse ethnic populations remain controversial. Method: A case-control genetic study performed from September 2013 April 2014 2015. All samples were tested for using RT-PCR, genotyped...
Abstract Background Twelve students experienced symptoms of acute respiratory infection (ARI) at a training base in Beijing from August 26 to 30, 2015. We investigated the cause this ARI outbreak. Methods In partnership with local center for disease control, we collected total twelve pharyngeal swab specimens as well demographic information affected patients. used multiplex real-time PCR screen sixteen common viruses these samples. To isolate HAdV, inoculated Hep-2 cells human adenovirus...
Abstract Naked carp ( Gymnocypris przewalskii ), endemic to the saline-alkaline Lake Qinghai, have capacity tolerate combinations of high salinity and alkalinity, but migrate spawn in freshwater rivers each year. In this study, we measured drinking rate over a 24 h period for naked exposed lake waters with salinities 15 (L15) 17 (L17). We also assessed daily feed intakes L15 fresh water (FW). Additionally, studied expression acid–base regulation osmoregulation related genes proteins...
Many species of Schizothoracine, a subfamily Cyprinidae, are highly endemic to the Qinghai-Tibetan Plateau (QTP). To characterize adaptive changes associated with Schizothoracine expansion at high altitudes, we sequenced tissue transcriptomes two highland and subhighland Schizothoracines analyzed gene evolution patterns by comparing lowland cyprinids. Phylogenetic tree reconstruction divergence time estimation indicated that common ancestor fish lived ∼32.7 million years ago (MYA),...