A5100361398- Phytochemicals and Antioxidant Activities
- Genomics, phytochemicals, and oxidative stress
- Plant Gene Expression Analysis
- Phytochemistry and Biological Activities
- Natural Antidiabetic Agents Studies
- Plant biochemistry and biosynthesis
- Food Quality and Safety Studies
- Microbial Metabolites in Food Biotechnology
- Natural Fiber Reinforced Composites
- Free Radicals and Antioxidants
- Ginkgo biloba and Cashew Applications
- Phytoestrogen effects and research
- Computer Graphics and Visualization Techniques
- Thermal Analysis in Power Transmission
- Medicinal Plants and Neuroprotection
- Cell death mechanisms and regulation
- Natural product bioactivities and synthesis
- Meat and Animal Product Quality
- Glutathione Transferases and Polymorphisms
- Seed and Plant Biochemistry
- Interactive and Immersive Displays
- 14-3-3 protein interactions
- Tea Polyphenols and Effects
- Mycotoxins in Agriculture and Food
- Cardiovascular Health and Risk Factors
Shenyang Agricultural University
2013-2024
Huazhong University of Science and Technology
2023
State Council of the People's Republic of China
2020-2022
Xuzhou Medical College
2022
Second Affiliated Hospital of Xuzhou Medical College
2022
Chinese Academy of Agricultural Sciences
2021
Institute of Food Science and Technology
2021
Ministry of Agriculture and Rural Affairs
2021
China Pharmaceutical University
2015
Rothamsted Research
2008
The amounts and compositions of free, conjugated, bound, total phenolic acids were determined in 175 samples wheat flour grown on a single site 2005. highest contents found flours winter (1171 microg/g) with average levels 658 microg/g phenolics across all the genotypes. Winter wheats showed range >3.5-fold concentration for acids. Spelt genotypes displayed narrowest (1.9-fold) acid concentration. concentrations different fractions order bound > conjugated making up around 77% free...
Induction of phase II antioxidant enzymes by activation Nrf2/ARE pathway has been recognized as a promising strategy for the regulation oxidative stress-related diseases. Herein we report our effort on discovery and optimization Nrf2 activators with 1,2,4-oxadiazole core. Screening an in-house collection containing 7500 compounds ARE-luciferase reporter assay revealed moderate activator, 1. Aimed at obtaining more derivatives efficiently, molecular similarity search combination 2D...
We investigated the cytoprotective effects of anthocyanins in Aronia melanocarpa against apoptosis induced by Aβ1-42, a key mediator AD pathophysiology. measured intracellular calcium with colorimetric kit, cellular DAPI, ROS fluorescent marker 2,3-dimethoxy-1,4-naphthoquinone, mitochondrial membrane potential JC-1, and ATP kit. Gene transcription protein expression levels calmodulin, cytochrome c, caspase-9, cleaved caspase-3, Bcl-2, Bax were analyzed RT-PCR Western blotting. The results...
Polyphenols are the main active components of anti-inflammatory compounds in dandelion, and chlorogenic acid (CGA) is one primary polyphenols. However, molecular mechanism underlying transcriptional regulation CGA biosynthesis remains unclear. Hydroxycinnamoyl-CoA:quinate hydroxycinnamoyl transferase (HQT2) last rate-limiting enzyme Taraxacum antungense. Therefore, using TaHQT2 gene promoter as a probe, yeast one-hybrid library was performed, basic helix-loop-helix (bHLH) transcription...
The anthocyanins extracted from Aronia melanocarpa are of great interest because their potential health-related functionalities. However, poor stabilities have limited use in applications. Hence, to improve physical and oxidative stability, we optimised the chitosan nanocapsules encapsulating melanocarpa, evaluated systems terms physicochemical characteristics, oxidant stability simulated gastrointestinal digestion different storage environments. Results show that obtained present favorable...
The protective effects of Lonicera caerulea berry extract (LCBE) against hepatic inflammation and the underlying mechanisms were investigated in a rat model lipopolysaccharide (LPS)-induced chronic liver inflammation. Male Sprague-Dawley rats injected with LPS (200 μg per kg bw) or without LCBE co-administration (50, 100 200 mg bw intragastrically once daily) for 4 weeks. We found that supplementation inhibited increase Toll-like receptor (TLR)2 TLR4 expression induced by LPS, while...
Vaccinium uliginosum L. (VU), rich in polyphenols, is an important wild berry resource primarily distributed extremely cold regions. However, the detailed composition of polyphenols (VUPs) has not been reported, which limits development and utilization VU. In this study, VU-free (VUFPs) VU-bound (VUBPs) were, respectively, extracted using ultrasonic, complex enzyme alkali extraction method; compositions were identified ultra-performance liquid chromatography–electrospray ionization mass...
The in vivo applications of anthocyanins are limited by their instability. Nano-encapsulation using amylopectin nanoparticles (APNPs) stabilizes to deliver them tissues ameliorate physiological functions. Herein, rats fed four Aronia melanocarpa encapsulated with APNPs, and subsequent distributions bioactivity nine revealed UHPLC–MS. Among digestive tissues, the concentration APNP-protected cyanidin 3-O-arabinoside stomach is 134.54% that free anthocyanin, while among non-digestive...
Anthocyanins of Aronia melanocarpa are known for their therapeutic properties; however, they unstable and easily degrade in the environment vivo .
Abstract The development of structure-activity relationships (SAR) emerges as a crucial strategy to establish the correlations between molecular micro-parameters and macroscopic dielectric strength, thus markedly improving gases screening efficiency. However, conventional prediction approaches have failed characterize molecule electronegativity accurately, resulting in inadequate precision within extensive gas databases. To address this limitation, we devised an insulation method that...
In this paper, laboratory glassware with different nature of dirt and experimental requirements is required to choose washing methods.
Physical and chemical properties were measured to study quality of 5 strawberry cultivars, which fruit weight, firmness, vitamin C, total sugar, anthocyanin, phenols, pH, soluble solid, titratable acid, crude protein juice yield. The result showed that PC1 explained 54.519% the variance in data set, PC2 28.184% PC3 9.252%. Accumulative contribution these three main compositions extracted by principal component analysis was 91.954%. Eleven could reduce components, five cultivars distinguished...