A5100429184- Plant-based Medicinal Research
- Research in Cotton Cultivation
- Bioactive Natural Diterpenoids Research
- Animal Ecology and Behavior Studies
- Neuroendocrine regulation and behavior
- Advanced Drug Delivery Systems
- Biological and pharmacological studies of plants
- Alkaloids: synthesis and pharmacology
- Ginseng Biological Effects and Applications
- Nanoparticle-Based Drug Delivery
- Genetic and phenotypic traits in livestock
- Nanoplatforms for cancer theranostics
- Plant Gene Expression Analysis
- Bat Biology and Ecology Studies
- Wildlife Ecology and Conservation
- Atherosclerosis and Cardiovascular Diseases
- Nerve injury and regeneration
- Neurobiology and Insect Physiology Research
- Environmental Changes in China
- Natural product bioactivities and synthesis
- Species Distribution and Climate Change
- Plant and Fungal Interactions Research
- Biological Activity of Diterpenoids and Biflavonoids
- Biological Research and Disease Studies
- Plant pathogens and resistance mechanisms
Translational Therapeutics (United States)
2024
University of Pennsylvania
2024
Nanjing Medical University
2024
Gansu Agricultural University
2018-2023
Hebei Agricultural University
2021-2023
Hubei University
2023
Beijing University of Chinese Medicine
2021-2022
Waterborne Environmental (United States)
2022
Applied Radar (United States)
2022
Sichuan Agricultural University
2021
Abstract Cotton produces natural fiber for the textile industry. The genetic effects of genomic structural variations underlying agronomic traits remain unclear. Here, we generate two high-quality genomes Gossypium hirsutum cv. NDM8 and barbadense acc. Pima90, identify large-scale in species 1,081 G . accessions. density is higher D-subgenome than A-subgenome, indicating that undergoes stronger selection during formation variety development. Many genes and/or regulatory regions potentially...
This study reports the development of novel drug delivery complexes self-assembled by divalent metal ion-assisted coacervation for controlled and sustained release a hydrophilic small molecule minocycline hydrochloride (MH). MH is multifaceted agent that has demonstrated therapeutic effects in infection, inflammation, tumor, as well cardiovascular, renal, neurological disorders due to its anti-microbial, anti-inflammatory, cytoprotective properties. However, inability translate high doses...
Crops must efficiently allocate their limited energy resources to survival, growth and reproduction, including balancing defense. Thus, investigating the underlying molecular mechanism of crop under stress is crucial for breeding. Chloroplasts immunity an important facet involving in plant resistance growth, however, whether how modulated by chloroplast influenced epigenetic regulation remains unclear. Here, cotton lysine 2-hydroxyisobutyrylation (Khib) succinylation (Ksuc) modifications are...
Magnetic nanoparticles(NPs) are characterized by a rich variety of properties. Because their excellent physical and chemical properties, they have come to the fore in biomedicine other fields. The magnetic NPs were extensively studied separation cells, targeted drug delivery, tumor hyperthermia, chemo-photothermal therapy, resonance imaging (MRI) biomedical increasingly used based on inherent targeting, superparamagnetic enzyme-like catalytic properties nanoscale size....
As agents in an emerging technology, Hermetia illucens (Linnaeus, 1758) (Diptera: Stratiomyidae) larvae, black soldier fly, have shown exciting potential for degrading antibiotics organic solid waste, a process which gut microorganisms play important role. This study investigated the characteristics of larval bacterial communities effected by typical antibiotics. Initially, significantly reduced diversity species. After 8 days, recovered to similar that control group chlortetracycline,...
Verticillium wilt (VW), a fungal disease caused by dahliae, currently devastates cotton fiber yield and quality seriously, yet few resistance germplasm resources have been discovered in Gossypium hirsutum. The variety Nongda601 with suitable VW high was developed our lab, which supplied elite for discovering resistant genes. Early nodulin-like protein (ENODL) is mainly related to nodule formation, its role regulating defense response has seldom studied. Here, 41 conserved ENODLs G. hirsutum...
The comprehensive antiatherosclerosis effects of TPNP include reducing ROS production and regulating the phenotypic polarization macrophages.
In recent decades, nucleic acid self-assemblies have emerged as popular nanomaterials due to their programmable and robust assembly, prescribed geometry, versatile functionality. However, it remains a challenge purify large quantities of DNA nanostructures or DNA-templated nanocomplexes for various applications. Commonly used purification methods are either limited by small scale incompatible with functionalized structures. To address this unmet need, we present scalable method purifying...
Growth is a complex trait with moderate to high heritability in livestock and must be described by the longitudinal data measured over multiple time points. Therefore, used phenotype genome-wide association studies (GWAS) of growth traits could either measures at preselected point or fitted parameters whole trajectory. A promising alternative approach was recently proposed that combined fitting curves estimation single-nucleotide polymorphism (SNP) effects into single-step nonlinear mixed...
The increased population density of rodent species during ongoing grassland degradation further deteriorates its conditions. Understanding the effects on feeding habits is great value for optimizing management strategies. In this study, lightly degraded (LD), moderately (MD), severely (SD), and reseeded (RG) were selected their plant resources soil physical properties investigated. addition, study used ITS2 barcode combined with Illumina MiSeq sequencing method to analyze food composition...
To investigate the hypoglycemic components from acid hydrolyzates of Panax quinquefolius total saponins, and screen active compounds by in vitro inhibitory activities to α-glycosidase enzymes protein tyrosine phosphatase-1B (PTP1B).The were chromatographed repeatedly over silica gel column, structures determined means NMR. The bioassay was performed through effects on α-glucosidase or/and PTP1B.Eight isolated, which identified as 20(S)-panaxadiol (1),...
Risk taking is imperative for the survival and fitness of animals since they constantly face innumerable threats from various sources. Indeed, ability individual to balance between costs benefits options adopt a wise decision critical well-being animal. In current study, we investigated gender differences in risk making male female Smith's zokors (Eospalax smithii), subterranean rodent species, defensive withdrawal apparatus (DWA) under novel, predator conditioned contexts. Under novel...
Semen Euphorbiae (SE), the dry and mature seed of Euphorbia lathyris L., a common traditional Chinese medicine, has significant pharmacological activity. However, its toxicity limits clinical application, less toxic Pulveratum (SEP) is often used clinically. To explore possible mechanism SE frost-making attenuation, this study ultrahigh-performance liquid chromatography coupled with quadrupole time flight mass spectrometry to perform comprehensive metabolomics analysis serum urine samples...
In order to evaluate the safe and stable operation of distribution network with distributed photovoltaic (PV), security is researched.On basis electricity supply security, voltage quality losses, index system static established.The paper simulates uncertainty random characteristics PV by OpenDSS.The typical scenes that accessed are designed.The summarizes results fluctuation losses uses indices quantify it under different scenes.Based on system, proposes some recommendations permeability,...
With the growing popularity of smart phones and richness Geographic information databases, map-based applications have become an indispensable part in people's daily life. However there is a common problem online maps which high consumption network traffic. Using offline good solution to this problem. During development NKCampus online/offline map application, we find that some are very inefficient because their simple database mechanism. Therefore present multi-level caches method improve...
Previous pharmacological studies have indicated that diterpenoids are the primary effective chemical cluster in seeds of Euphorbia lathyris L. The seed products used traditional Chinese medicine forms Semen Euphorbiae (SE) and Pulveratum (SEP). However, metabolism plant's has not been well elucidated, which means vivo metabolite identified. current study screened physiological metabolites six diterpenes [Euphorbia factor L1 (L1), L2 (L2), L3 (L3), L7a (L7a), L7b (L7b), L8 (L8)] feces urine...