A5103090531- Advanced Glycation End Products research
- Natural Antidiabetic Agents Studies
- Silymarin and Mushroom Poisoning
- Biomedical Research and Pathophysiology
- Pharmacological Effects of Natural Compounds
- Cancer Research and Treatments
- Sarcoma Diagnosis and Treatment
- Biochemical effects in animals
- Cancer Cells and Metastasis
- Fault Detection and Control Systems
- Drug-Induced Hepatotoxicity and Protection
- Surfactants and Colloidal Systems
- Anomaly Detection Techniques and Applications
- Protein Interaction Studies and Fluorescence Analysis
Ministry of Industry and Information Technology
2024
Beihang University
2024
Tianjin University
2021-2024
Renji Hospital
2022
Zoucheng People's Hospital
2021
As a natural flavonolignan, silibinin is reported to possess multiple biological activities, while the inhibitory potential of on carbohydrate-hydrolyzing enzymes still unclear. Therefore, in this study, effect and underlying mechanism against α-amylase/α-glucosidase were investigated. The results indicated that showed strong efficiency noncompetitive manners exhibited synergistic inhibition α-glucosidase with acarbose. However, interestingly, was significantly hindered various milk...
To retrospectively analyze and compare the relationship between success rate of patient-derived xenograft (PDX) modeling osteosarcoma prognosis (3-year overall survival disease-free rate) incidence lung metastasis.The sample group consisted 57 patients with definite pathological diagnoses from Shanghai General Hospital 2015-2017. PDX models in were analyzed by retrospective analyses. Among currently inoculated, 20 tumorigenic model, 37 nontumorigenic. According to tumorigenicity PDXs,...
With the continuous popularization of smart medicine, protective effect silibinin in liver has attracted much attention. This study mainly explores protection mechanism and absorption promotion technology silybin based on intelligent medical analysis. Refining silibinin: accurately weigh 1.0 g a three-necked flask; gradually add 50 mL anhydrous methanol, reflux filter precipitated solid; it after drying. ICR male mice were taken as experimental subjects randomly divided into groups 10 each....