A5100456922- Traditional Chinese Medicine Analysis
- Ginseng Biological Effects and Applications
- Corneal surgery and disorders
- Glaucoma and retinal disorders
- Intraocular Surgery and Lenses
- Natural Antidiabetic Agents Studies
- Phytochemicals and Medicinal Plants
- Neurological Disease Mechanisms and Treatments
- Biosensors and Analytical Detection
- Antibiotics Pharmacokinetics and Efficacy
- Traditional Chinese Medicine Studies
- Phytochemistry and Biological Activities
- Head and Neck Cancer Studies
- Mass Spectrometry Techniques and Applications
- Cytokine Signaling Pathways and Interactions
- Computational Drug Discovery Methods
- Muscle activation and electromyography studies
- Protein Interaction Studies and Fluorescence Analysis
- Medical Research and Treatments
- Advanced Radiotherapy Techniques
- Corneal Surgery and Treatments
- Endometriosis Research and Treatment
- Uterine Myomas and Treatments
- Chromatography in Natural Products
- Global Maternal and Child Health
Guiyang Medical University
2025
Jiading District Central Hospital
2024
Chengdu Second People's Hospital
2024
Nanjing University of Science and Technology
2024
Sanya Central Hospital
2024
Ruijin Hospital
2024
Shanghai Jiao Tong University
2024
Peking University
2014-2023
Hubei University of Medicine
2023
Taihe Hospital
2023
As a natural flavonolignan, silibinin is reported to possess multiple biological activities, while the inhibitory potential of on carbohydrate-hydrolyzing enzymes still unclear. Therefore, in this study, effect and underlying mechanism against α-amylase/α-glucosidase were investigated. The results indicated that showed strong efficiency noncompetitive manners exhibited synergistic inhibition α-glucosidase with acarbose. However, interestingly, was significantly hindered various milk...
ABSTRACT Deubiquitinating enzymes (DUBs) are integral regulators of protein stability. Among these, Ubiquitin‐specific protease 18 (USP18) has emerged as a potential therapeutic target for heart failure. However, its precise role in atherosclerosis remains to be comprehensively understood. This study endeavours examine the impact USP18 on and elucidate corresponding molecular mechanisms. Our studies indicate an elevated expression human coronary atherosclerotic plaques. Notably, knockdown...
This study investigates the application of artificial fish swarm algorithm (AFSA) in power allocation for multiple-input and multiple-output orthogonal frequency-division multiplexing (MIMO-OFDM) relay underwater acoustic (UWA) communication systems. First, by using singular value decomposition technique, two-hop transmission links are converted into virtual direct an single-input single-output OFDM (SISO-OFDM) system. Then, a optimisation problem, together with assignment subcarriers nodes,...
Two new pimarane diterpenes, libertellenone M (1) and N (2), together with five known compounds were isolated from the culture extract of Eutypella sp. D-1 derived high-latitude soil Arctic. The structures these determined by spectroscopic data as well experimental calculated electronic circular dichroism (ECD) analysis. Antimicrobial cytotoxic activities evaluated. Compound 3 exhibited weak antibacterial activity against Escherichia coli, Bacillus subtilis, Vibrio vulnificus, each MIC...
A method has been developed which allows direct measurement of partition coefficients (log D, log P) using liquid chromatography-mass spectrometry (LC-MS). The high throughput, microtiter plate based protocol uses small quantities 10 mM analyte in DMSO solution (5 microL) and is therefore amenable to standard archive screening formats. Single Ion Monitoring (SIM) mass used achieve optimal sensitivity. Experimental D values for 34 known drugs have determined, with ranging from -2 5, giving...
Transradial approach is the classical access for coronary angiography and percutaneous intervention (PCI). With increase in number of interventional procedures, some disadvantages transradial have also been found, it easy to lead various complications, such as radial artery occlusion, nerve injury, puncture difficulties after spasm. Therefore, experts put forward distal therapy, which has advantages convenient positioning, postoperative hemostasis, less damage proximal improving patients'...
A simple and reliable method for distinguishing Danshen is important to evaluate the quality clinical efficiency of these species. An HPLC was developed determination protocatechuic aldehyde, salvianolic acid A, B, cryptotanshinone, tanshinone I IIA in 23 samples Salvia. The analytes were separated on an Agilent XDB C18 reversed-phase column coupled with a Phenomenex guard using gradient elution acetonitile–0.1% aqueous phosphoric as mobile phase at flow rate 0.8 mL/min UV detection 280 nm....
The chemical components of Huanglian Decoction were identified by ultra-performance liquid chromatography-quadrupole-time-of-flight-tandem mass spectrometry(UPLC-Q-TOF-MS/MS) technology. gradient elution was conducted in Agilent ZORBAX Extend-C_(18) column(2.1 mm×100 mm, 1.8 μm) with the mobile phase 0.1% formic acid aqueous solution(A)-acetonitrile(B) at a flow rate 0.3 mL·min~(-1) and column temperature 35 ℃. MS adopted positive negative ion mode electrospray ionization(ESI), data...
Introduction Venous thromboembolism (VTE) risk assessment at admission is of great importance for early screening and timely prophylaxis management during hospitalization. The purpose this study to develop validate novel models based on machine learning (ML) methods. Methods In retrospective study, a total 3078 individuals were included with their Caprini variables within 24 hours admission. Then several ML built, including logistic regression (LR), random forest (RF), extreme gradient...
In a response to growing demand for environments of 70dB or less noise levels, many industrial sectors have focused with some form control system. Active (ANC) has proven be the most effective technology. This paper mainly investigates application neural network on self-adaptation system in active (ANC). An silencing is made which adopts motional feedback loudspeaker as not controlling source but detecting sensor. The working fundamentals and characteristics are analyzed detail. By analyzing...
A high-performance liquid chromatography (HPLC) method has been developed for the simultaneous identification and quantification of active compounds (cryptotanshinone, dihydrotanshinone I, tanshinone IIA, salvianolic acid A, B, protocatechuic aldehyde, rosmarinic acid) contained in traditional Chinese folk medicine Salvia przewalskii Maxim. The herb samples (including wild, cultivated, yin pian) from fourteen main regions were investigated. Chromatographic separation was performed on an...
This study aims to compare the clinical efficacy of myomectomy and total hysterectomy in treatment perimenopausal uterine fibroids.124 cases fibroids were randomly divided into a control group group, each with 62 cases.The underwent hysterectomy.Study participants myomectomy.Both groups patients observed compared for surgery-related indicators, quality life scores, syndrome inflammatory factors.The had shorter operation time less intraoperative blood loss (p < 0.05).Before operation, there...