A5003235159- Platelet Disorders and Treatments
- Autoimmune Bullous Skin Diseases
- Blood groups and transfusion
- Extracellular vesicles in disease
- Chronic Lymphocytic Leukemia Research
- Circular RNAs in diseases
- MicroRNA in disease regulation
- Lipid metabolism and disorders
- Phytochemistry and Biological Activities
- Antifungal resistance and susceptibility
- Phytochemicals and Antioxidant Activities
- Metal-Organic Frameworks: Synthesis and Applications
- Immunodeficiency and Autoimmune Disorders
- Cancer-related molecular mechanisms research
- Cell Adhesion Molecules Research
- Membrane Separation Technologies
- Blood properties and coagulation
- Antibiotic Resistance in Bacteria
- Immune Cell Function and Interaction
- Blood Pressure and Hypertension Studies
- Medicinal Plants and Bioactive Compounds
- Neonatal Respiratory Health Research
- Hormonal Regulation and Hypertension
- Antioxidant Activity and Oxidative Stress
- Crystallization and Solubility Studies
Qilu Hospital of Shandong University
2016-2025
Shandong First Medical University
2019-2024
Shandong Tumor Hospital
2019-2024
Peking University
2020-2024
University of Bristol
2023-2024
Air Force Medical University
2024
Fuwai Yunnan Cardiovascular Hospital
2022-2024
Red Cross Hospital
2024
Weifang Medical University
2024
Academy of Medical Sciences
2024
Beyond their pore structures and surface chemistry, precise controls over other attributes of metal-organic frameworks (MOFs) such as shapes, sizes, defects are also favorable to fundamental studies applications but still remain challenging. Herein, we reported an acid/base co-modulation strategy the large-scale synthesis monodisperse UiO-66 crystals with acetic acid for modulating crystal shape triethylamine (TEA) a base controlling nucleation crystallization tuning formation missing linker...
Abstract Background To identify specific exosomal microRNAs (miRNAs) as serum biomarkers for prediction of metastasis in patients with colorectal cancer (CRC). Materials and Methods Serum exosomes were isolated from metastatic CRC (n = 34) non‐metastatic 108) by ultracentrifugation characterized using transmission electron microscopy, qNano, Western blot. Differential miRNAs screened sequencing validated qPCR patients. Results After sequence analysis, KEGG analysis showed that differential...
Abstract Background KDM6A, a histone demethylase, is frequently mutated in bladder cancer (BCa). However, the role and detailed molecular mechanism of KDM6A involved progression remains unknown. Methods Tissue specimens were used to determine expression levels prognostic values ARHGDIB. The MTT, colony formation, wound healing Transwell migration invasion assays employed detect BCa cell proliferation, invasion, respectively. Chemotaxis macrophages was evaluate ability recruit macrophages. A...
Abstract Background In recent years,the lack of specific markers for the diagnosis colorectal cancer has led to an upward trend in both morbidity and mortality from this condition. There is urgent need identify molecular biomarkers that contribute early detection. This study aimed exosomal microRNAs hold potential as diagnostic CRC. Methods We screened differentially expressed miRNAs using CRC exosome dataset GSE39833. To validate results public database, we collected serum 168 patients...
In this paper, we adopt a template matching method to detect design patterns from software system by calculating their normalized cross correlation. Because document flexible ideas, there can be various ways of implementing them. our approach, not only the exact matches pattern instances are detected source code, but also variations candidates identified. Based on method, provide tool support and perform experiments different large open-source systems.
Osmanthus fragrans flower extract (OFE) is an organic from O. flower, which exhibits neuroprotective, free radical scavenging, and antioxidant effects. Therefore, the protective effect of OFE acteoside against aging was studied. An ICR mouse model established by chronically administering d-galactose (250 mg/kg) for 8 weeks. induced spatial learning memory impairments that were successfully inhibited acteoside, could shorten escape latency, improve platform crossing times, increase zone time....
Processing metal-organic frameworks (MOFs) as films with controllable thickness on a substrate is increasingly crucial for many applications to realize function integration and performance optimization. Herein, we report facile cathodic deposition process that enables the large-area preparation of uniform zeolitic imidazolate (ZIF-8, ZIF-71, ZIF-67) highly tunable ranging from approximately 24 nm hundreds nanometers. Importantly, this oxygen-reduction-triggered does not lead plating reduced...
Summary Primary immune thrombocytopenia (ITP) is a haemorrhagic disorder with complex pathogenesis, wherein autoreactive B‐cell‐mediated platelet destruction plays crucial role. Bruton's tyrosine kinase (BTK) widely expressed and essential for cells. Several BTK inhibitors have been used clinically to treat haematological malignancies, while few studies are focusing on the regulatory role of in ITP. This study aims explore feasibility underlying mechanisms novel inhibitor orelabrutinib...
Cloud computing, a new paradigm of distributed introduces many ideas, concepts, principals, technologies and architectural styles into enterprise service-oriented computing. The architecture (ESOA) style is an abstraction concrete service-orientated architectures, which includes SOA elements, service design patterns as well principles, quality attributes. It can be extended to for realizing cloud Meanwhile, the principles computing facilitate enterprise-wide adoption This paper extends ESOA...