A5102732951- Voice and Speech Disorders
- Head and Neck Cancer Studies
- Cancer-related Molecular Pathways
- Gut microbiota and health
- Healthcare and Venom Research
- Ecology and Conservation Studies
- Pelvic floor disorders treatments
- Neonatal Respiratory Health Research
- Respiratory Support and Mechanisms
- Anorectal Disease Treatments and Outcomes
- TGF-β signaling in diseases
- Probiotics and Fermented Foods
- Congenital gastrointestinal and neural anomalies
- Intraocular Surgery and Lenses
- Tracheal and airway disorders
- Cancer Treatment and Pharmacology
- Congenital heart defects research
- Gastrointestinal motility and disorders
- Glaucoma and retinal disorders
- Genetic factors in colorectal cancer
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Lung Cancer Treatments and Mutations
- Ear and Head Tumors
- Ophthalmology and Eye Disorders
- HER2/EGFR in Cancer Research
Fujian University of Traditional Chinese Medicine
2020-2022
National Health and Family Planning Commission
2022
Chongqing Medical and Pharmaceutical College
2019
South China Agricultural University
2016
ShenZhen People’s Hospital
2016
National Natural Science Foundation of China
2015
University of Hong Kong
2015
To investigate the prevalence and risk factors of enlarged blind spots in non-pathological highly myopic eyes. Visual field conditions 313 eyes 172 individuals with high myopia were evaluated. Clinical characteristics 116 normal visual fields compared. Generalized-estimating equation (GEE) regression model used to assess associated spots. The frequency was 37.06% this sample. Eyes had larger gamma zone (P = 0.038), PHOMS area < 0.001), increased peripapillary retinal nerve fiber layer...
The expression profiles of miRNAs in thymus tissues from mice different age have been demonstrated our previous study. After an integrated analysis the miRNA profiles, we that miR-181a-5p was significantly decreased thymic epithelial cells (TECs) 10- to 19-month-old when compared with TECs 1-month-old by quantitative reverse transcriptase polymerase chain reaction. We hypothesized might be associated age-related involution through regulating some genes or signaling pathway. To test this...
Abstract This study aimed to compare the accuracy of CT and MRI in determining invasion thyroid cartilage by T staging laryngeal carcinoma with anterior vocal commissure (AVC) involvement. A total 26 cases carcinomas AVC involvement from May 2012 January 2014 underwent enhanced scan, out whom 6 patients also diffusion-weighted magnetic resonance imaging(DWI). were evaluated. All surgical specimens serial section reviewed two senior pathologists independently. When compared pathologic...
Abstract In this study, the self-extracted constipation treatment of traditional Chinese medicine extracts was applied to constipated rats. To explore mechanism and role for constipation, 16S rRNA sequencing qRT-PCR technology were used analyze intestinal flora. We found that relative abundance Firmicutes with significantly higher accounted 86.7%, while gut microbiota changed after taking a certain dose medicine, greatly increased Lactobacillus 23.1%, enhanced symbiotic relationships other...
Abstract Cyclin-dependent kinase-4 (CDK4) and CDK6 form a complex with D-type cyclins to phosphorylate Retinoblastoma protein (Rb), leading loss of repression E2F transcription factors, which enables cell cycle progression from G1 S phase. Loss control caused by aberrations in CDK/Rb signaling pathway are common solid tumors. Inhibiting CDK4/6 blocks pathway, prevents through restriction point, thus arresting tumor growth. Most the 1st generation CDK inhibitors lack family selectivity,...
This article explores the features and role of anterior vocal commissure (AVC) structure surface morphologies glottic carcinomas with AVC involvement to provide a reference for selection transoral carbon dioxide (CO2) laser surgery. A total 31 cases from May 2012 January 2014 were included. All patients underwent electronic laryngoscopic examinations computed tomography scans determine morphology. After surgery, tumor specimens resected integrally, axial serial sections parallel plane cords...
<title>Abstract</title> <bold>Purpose:</bold>To investigate the clinical features of prelaminar schisis (PLS) in highly myopic eyes. <bold>Methods: </bold>This cross-sectional studyincluded 245 eyes with high myopia and 93 low to moderate myopia. PLS was classified on a 3-point scale from 0 2. Clinical characteristics two groups were compared. Factors associated presence severity its correlation visual field evaluated. <bold>Results: </bold>Highly presented higher frequency...
Three-dimensional high-resolution anorectal manometry (3DHRAM) is a new technique that can explore disorders and provide interesting topographic data for the diagnosis of pelvic floor such as paradoxical puborectalis syndrome (PPS). Our object was to evaluate whether 3DHRAM reliably diagnose PPS already diagnosed with X-ray defaecography, which considered be gold standard. All patients being tested in our department dyschezia by 3D-HRAM defecography were eligible study. The results compared...