A5082709168- Plant Parasitism and Resistance
- Plant Molecular Biology Research
- Plant and animal studies
- biodegradable polymer synthesis and properties
- Dendrimers and Hyperbranched Polymers
- Enzyme Catalysis and Immobilization
- Liquid Crystal Research Advancements
- Supramolecular Chemistry and Complexes
- Advanced Synthetic Organic Chemistry
- Magnetism in coordination complexes
- Proteoglycans and glycosaminoglycans research
- Photochromic and Fluorescence Chemistry
- X-ray Diffraction in Crystallography
- Crystallization and Solubility Studies
- Allelopathy and phytotoxic interactions
- Viral Infectious Diseases and Gene Expression in Insects
- Quinazolinone synthesis and applications
- Mechanical and Optical Resonators
- Force Microscopy Techniques and Applications
- Glycosylation and Glycoproteins Research
- Polydiacetylene-based materials and applications
- Catalytic C–H Functionalization Methods
- Microbial Metabolites in Food Biotechnology
- Chemistry and Chemical Engineering
- Photoreceptor and optogenetics research
Kyoto University
2022-2025
ETH Zurich
2019-2023
Syngenta (Switzerland)
2022-2023
Nagoya University
2015-2018
University of Pennsylvania
1977
Germination signals illuminated The noxious weed Striga can take down an entire crop. Fields in Africa are particularly susceptible to the devastation it cause. seeds germinate response faint traces of hormone strigolactone released by its targets. Tsuchiya et al. designed a mimic that, when cleaved receptor, generates fluorescent end product. This photogenic lit up upon germination and led identification receptor. Abolishing activity this receptor could be effective defensive strategy....
Maize (Zea mays) is a major staple crop in Africa, where its yield and the livelihood of millions are compromised by parasitic witchweed Striga. Germination Striga induced strigolactones exuded from maize roots into rhizosphere. In germplasm collection, we identified two strigolactones, zealactol zealactonoic acid, which stimulate less germination than strigolactone, zealactone. We then showed that single cytochrome P450, ZmCYP706C37, catalyzes series oxidative steps maize-strigolactone...
Aromaticity of photoexcited molecules is an important concept in organic chemistry. Its theory, Baird's rule for triplet aromaticity since 1972 gives the rationale photoinduced conformational changes and photochemical reactivities cyclic π-conjugated systems. However, it still challenging to monitor dynamic structural change induced by excited-state aromaticity, particularly condensed materials. Here we report direct observation a molecular motion subsequent packing deformation accompanied...
Photocleavable molecules are valuable tools for biological studies, enabling spatiotemporal activation of molecular functions within cellular environments. In particular, coumarin-based photolytic useful because their ability to flexibly tune the wavelength photostimulation through structural modifications. Ideal photocleavable require hydrolytic stability and selective susceptibility photo stimuli. However conventional have not simultaneously achieved both highly efficient photocleavage...
Photocleavable molecules are valuable tools for biological studies, enabling spatiotemporal activation of molecular functions within cellular environments. In particular, coumarin‐based photolytic useful because their ability to flexibly tune the wavelength photostimulation through structural modifications. Ideal photocleavable require hydrolytic stability and selective susceptibility photo stimuli. However conventional have not simultaneously achieved both highly efficient photocleavage...
Photocleavable molecules are valuable tools for biological studies, enabling spatiotemporal activation of molecular functions within cellular environments. In particular, coumarin‐based photolytic useful because their ability to flexibly tune the wavelength photostimulation through structural modifications. Ideal photocleavable require hydrolytic stability and selective susceptibility photo stimuli. However conventional have not simultaneously achieved both highly efficient photocleavage...
Incorporation of sulfate into sulfated proteoglycans by isolated chicken chondrocytes was inhibited up to 74% transformation with the Rous sarcoma virus, and a similar inhibitory effect observed on acetate incorporation chondroitin sulfate. Slower sedimenting appear after viral transformation. The ratio 4-sulfate 6-sulfate in these slower different from that normal chondrocytes, but chain lengths glycosaminoglycans produced transformed were not significantly different. Chondrocytes also...
Photocleavable molecules are widely used in fields such as materials science and chemical biology. In particular, coumarin-based photocleavable indispensable for photomanipulation techniques biology because of their ability to flexibly adjust the wavelength photostimulation through straightforward structural modifications. However, traditional have several limitations, including hydrolysis aqueous environments susceptibility intracellular carboxylesterases. Additionally, substituting bonds...
Abstract Strigolactones are one of the phytohormones, which have multiple activities on plant growth and development. Since these strigolactone highly associated with crop yield, use could be a promising technology in modern sustainable agriculture. The major strigolactones corn root exudates been identified as zealactone 1a/b zeapyranolactone. We recently disclosed first total synthesis together its biological activity corn. Herein, we describe design simplified analogues both corn‐derived...
Abstract Two new methods for selective deprotection of diphenylmethylsilyl (DPMS) ethers are described. Unmasking can be achieved with either catalytic amounts perfluoro‐1‐butanesulfonyl fluoride (a SuFEx reagent) under mild, aqueous micellar conditions, or using stoichiometric 18‐crown‐6 ether in ethanol.
Abstract Polycyclic aromatic hydrocarbons (PAHs) are an important family of molecules in science and technology. Amino‐substituted PAHs promising building blocks to create attractive for materials science. However, the synthetic limitations have hampered produce diverse structures amino‐substituted PAHs. Here we describe a novel efficient method access through electrocyclization highly reactive keteniminium species. We demonstrated synthesis various disclosed some their photophysical...
Cage-like molecules, assembled by the coordination of multiple metal ions and organic links, are pushing new frontiers in science due to their design flexibility resulting diverse unique chemical properties. This field has been advanced two close but distinct chemistry communities. Consequently, family molecules referred as cages (CCs) constituted metal-pyridine bonds or metal–organic (MOCs) based on dinuclear tetracarboxylates paddlewheel complexes each community had not reviewed...
Abstract We describe herein a high yielding and metal‐free methodology to access 9‐aminophenanthrene derivatives heterocyclic analogues starting from biaryl acetamides. The conversion of the substrates their corresponding keteniminium salts triggers spontaneous electrocyclization occurring at room temperature within few minutes. DFT Calculations competition reactions were carried out rationalize observed reactivity understand relative kinetics compared other known involving salts.
We demonstrated time-resolved electron diffraction and vibrational spectroscopy to characterize the structure dynamics of molecules in liquid crystal state. Our findings present ultrafast local deformation triggering helical twisting motion molecules.
寄生植物ストライガは作物の根に寄生し収量を大幅に減少させることから，アフリカを中心に大きな農業被害を及ぼしている．その被害は年間約1兆円にものぼり，人口増加の一途をたどるアフリカの食糧確保に向け早急に解決すべき問題となっている．ストライガは，寄生先となる植物が土壌中に放出するストリゴラクトンを認識して発芽する．この仕組みを明らかにすることはストライガ問題解決の糸口となるが，その鍵となるストリゴラクトン受容体は長い間未解明であった．本総説では，ストリゴラクトンについてのこれまでの知見を概説したのち，ストライガのストリゴラクトン受容体タンパク質同定及び発芽のメカニズム解明に関する最新の研究について紹介し，ストライガの発芽制御に向けた展望について述べる．