A5079377393- Asthma and respiratory diseases
- COVID-19 Clinical Research Studies
- Dialysis and Renal Disease Management
- SARS-CoV-2 and COVID-19 Research
- Gut microbiota and health
- IL-33, ST2, and ILC Pathways
- Musculoskeletal pain and rehabilitation
- COVID-19 epidemiological studies
- Spine and Intervertebral Disc Pathology
- Vaccine Coverage and Hesitancy
- SARS-CoV-2 detection and testing
- Cannabis and Cannabinoid Research
- Muscle and Compartmental Disorders
- Acute Kidney Injury Research
- Eosinophilic Esophagitis
- COVID-19 Impact on Reproduction
- Pain Management and Placebo Effect
- Chronic Kidney Disease and Diabetes
- Medicinal Plants and Neuroprotection
- Neurotransmitter Receptor Influence on Behavior
- Neurological Disease Mechanisms and Treatments
- Cancer Immunotherapy and Biomarkers
- Breastfeeding Practices and Influences
- Central Venous Catheters and Hemodialysis
- Inhalation and Respiratory Drug Delivery
Brigham and Women's Hospital
2022-2025
Chulalongkorn University
2020-2024
Harvard University
2021-2024
The proportion of incident cases HPV-attributable cancers is highest in the low- and middle-income countries (LMICs) but many are yet to initiate HPV vaccination programs. This meta-analysis was performed assess uptake LMICs at beginning global strategy eliminate cervical cancer describes gaps challenges.
Abstract Background Lung function is an independent predictor of mortality. We evaluated the lung trajectories a cohort patients with asthma receiving biologic therapy. Methods identified 229 monoclonal antibody‐naïve adult moderate‐to‐severe who initiated omalizumab, mepolizumab, or dupilumab between 2010 and 2022 in large healthcare system Boston, MA. Generalized additive mixed models were used to estimate during 156 weeks following initiation. Response was defined as improvement FEV 1...
Background Tuberculosis (TB) has contributed to a significant disease burden and economic loss worldwide. Given no gold standard for diagnosis, early identification of TB infection been challenging. This study aimed comparatively investigate the prevalence across diagnostic approaches (sputum AFB, sputum culture, genetic test, chest x-ray) geographical areas Indonesia. Methods Participant demographic variables screening test results were obtained from Unit, Health Research Development...
Background COVID-19 seroprevalence data, particularly in less developed countries with a relatively low incidence, has been scant. We aimed to explore the of hospital staff area zero confirmed case shed light on situation infection or rate where mass screening was not readily available. Methods A locally rapid immunoglobulin M (IgM)/immunoglobulin G (IgG) test kit used for Ranong which is located province prevalence Thailand from 17 th April May 2020. All tested, 100 were randomly invited...
We sought to evaluate the efficacy and complications of urgent-start peritoneal dialysis (PD) compared with temporary hemodialysis (HD) followed by subsequent elective transfer PD.In this multicenter open-label prospective randomized controlled trial, adults kidney failure who required immediate but did not have access definitive were receive either PD or HD over 2 weeks 4 a transition chronic program according country policy. The primary outcome was composite end point operation-related,...
During the early phase of COVID-19 pandemic, several countries, including Thailand, provided two shots CoronaVac to healthcare workers. Whereas ChAdOx1 nCoV-19 is promising vaccine as booster dose, data on immunogenicity when administered after have been limited. The purpose this study was evaluate third dose in workers who previously received CoronaVac. blood samples were obtained before vaccination and one month three months vaccination. All participants measured for humoral immunity...
Introduction We sought to evaluate the predictors and outcomes of mold peritonitis in patients with peritoneal dialysis (PD). Methods This cohort study included PD from MycoPDICS database who had fungal between July 2015-June 2020. Patient were analyzed by Kaplan Meier curves Log-rank test. Multivariable Cox proportional hazards model regression was used estimating associations types patients’ outcomes. Results The 304 episodes (yeasts n = 129, hyaline molds 122, non-hyaline 44, mixed fungi...
Abstract To date, most studies to identify biomarkers associated with response the anti-interleukin 5 agent, mepolizumab, and anti-immunoglobulin E omalizumab have focused on clinically available biomarkers, such as peripheral blood eosinophil counts (BEC) total immunoglobulin (IgE). However, these often low predictive accuracy, many patients eosinophilic or allergic asthma failing demonstrate clinical mepolizumab respectively. In this study, we evaluated association of baseline pre-biologic...
This describes variations in facility peritoneal dialysis (PD) effluent (PDE) culture techniques and local microbiology laboratory practices, competencies, quality assurance associated with peritonitis, a specific emphasis on factors culture-negative peritonitis (CNP).Peritonitis data were prospectively collected from 22 Thai PD centers between May 2016 October 2017 as part of the Peritoneal Dialysis Outcomes Practice Patterns Study. The first cloudy bags participants suspected sent to...
Several COVID-19 vaccination rollout strategies are implemented. Real-world data from the large-scale, government-mandated Central Vaccination Center (CVC), Thailand, could be used for comparing breakthrough infection, across all available profiles.This prospective cohort study combined vaccine profiles CVC registry with three nationally validated outcome datasets to assess hospitalization, and death among Thais individuals who received at least one dose of vaccine. The outcomes were...
Background There is limited evidence on biomarkers associated with response to the monoclonal antibodies currently approved for asthma treatment. We sought identify circulatory metabolites treatment mepolizumab or omalizumab. Methods conducted global metabolomic profiling of pre-treatment plasma samples from 100 patients moderate-to-severe who initiated (n=31) omalizumab (n=69). The primary outcome was change in exacerbations within 12 months therapy. Negative binomial models were used...