Masahiro Yamazaki

ORCID: 0000-0003-0433-7105
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About
Contact & Profiles
Research Areas
  • Vestibular and auditory disorders
  • Hearing, Cochlea, Tinnitus, Genetics
  • Cerebral Venous Sinus Thrombosis
  • Glaucoma and retinal disorders
  • Renal cell carcinoma treatment
  • Ophthalmology and Eye Disorders
  • Particle accelerators and beam dynamics
  • Particle Accelerators and Free-Electron Lasers
  • Renal and Vascular Pathologies
  • Gyrotron and Vacuum Electronics Research
  • Solid State Laser Technologies
  • Crystal Structures and Properties
  • Advanced MRI Techniques and Applications
  • Advanced Neuroimaging Techniques and Applications
  • Prostate Cancer Diagnosis and Treatment
  • Photorefractive and Nonlinear Optics
  • Renal and related cancers
  • Urologic and reproductive health conditions
  • Urological Disorders and Treatments
  • Bladder and Urothelial Cancer Treatments
  • Semiconductor Lasers and Optical Devices
  • Cerebrospinal fluid and hydrocephalus
  • MRI in cancer diagnosis
  • Neonatal and fetal brain pathology
  • Metastasis and carcinoma case studies

Jichi Medical University
2016-2024

Sapporo Kosei General Hospital
2024

Jichi Medical University Hospital
2020-2024

University of Tokyo Hospital
2024

Tochigi Medical Center
2023

Osaka University
1990-2022

Kouseiren Takaoka Hospital
2020

Nagoya University
2008-2018

Japan Atomic Energy Agency
2007

Advanced Science Research Center
2006

Heavily T2-weighted 3-dimensional fluid-attenuated inversion recovery (hT2W-3D-FLAIR) technique has been reported to be more sensitive than conventional 3D-FLAIR in detecting low concentrations of gadolinium-based contrast media (GBCM) fluid. We applied hT2W-3D-FLAIR visualize endolymphatic hydrops Ménière's disease 3 patients 4 hours after single-dose intravenous injection GBCM and successfully visualized either the cochlea or vestibule all patients. This can implemented a clinical setting.

10.2463/mrms.9.237 article EN Magnetic Resonance in Medical Sciences 2010-01-01

Conclusions: The blood–labyrinth barrier is impaired in association with the hydrops grade Ménière's disease. Objectives: To investigate relationship between endolymphatic and clinical characteristics of patients disease revealed by 3 T magnetic resonance imaging (MRI). Methods: A double dose gadoteridol (Gd; 0.2 mmol/kg) was injected intravenously 12 We performed three-dimensional fluid attenuated inversion recovery MRI real 4 h later using a unit. Ten had unilateral two bilateral Results:...

10.3109/00016489.2010.534114 article EN Acta Oto-Laryngologica 2011-01-03

For the separate visualization of endolymph, perilymph, and bone on a single image after intravenous injection single-dose gadodiamide, we fused gray-scale inverted positive endolymph (PEI) with native perilymph (PPI) images, that is, subtracted PEI from PPI. Subtraction significantly improved contrast noise ratio between subjective visibility score for endolymphatic space. The 24 patients suspect Ménière's disease were included.

10.2463/mrms.11.213 article EN Magnetic Resonance in Medical Sciences 2012-01-01

<h3>BACKGROUND AND PURPOSE:</h3> 3D-FLAIR imaging 24 hours after intratympanic gadolinium injection (IT-method) or 4 IV (IV-method) has been used to visualize the endolymphatic hydrops in Ménière disease. The purpose of this study was compare degree perilymph enhancement with 2 methods and contrast-effect difference IV-method both sides patients unilateral <h3>MATERIALS METHODS:</h3> Sixty-one disease sudden SNHL were included study. Thirty-nine who underwent IT-method (Gd-DTPA diluted...

10.3174/ajnr.a2821 article EN cc-by American Journal of Neuroradiology 2011-12-15

To visualize endolymph as bright signal after intravenous injection of single-dose gadodiamide, we shortened the inversion time heavily T(2)-weighted 3-dimensional (3D) fluid-attenuated recovery (FLAIR) to 2050 ms. In 14 patients with suspected Ménière's disease, observed high vestibular in all ears, including 6 ears without endolymphatic hydrops. We cochlear 17 hydrops but not 11

10.2463/mrms.11.145 article EN Magnetic Resonance in Medical Sciences 2012-01-01

Purpose: Heavily T2-weighted, 3-dimensional, fluid-attenuated inversion recovery (hT2W-3D-FLAIR) imaging has been reported to detect low concentrations of gadolinium-based contrast media (GBCM) in the anterior eye segment (AES), subarachnoid space (SAS), and labyrinthine perilymph as well cerebrospinal fluid (CSF) internal auditory canal (IAC) 4 hours after intravenous administration a single dose (IV-SD-GBCM) patients with inner ear disorders. To elucidate time course enhancement healthy...

10.2463/mrms.2013-0056 article EN Magnetic Resonance in Medical Sciences 2014-01-01

Purpose: Visualization of endolymphatic hydrops (EH) in patients with Ménière's disease (MD) is now possible by heavily T2-weighted 3-dimensional fluid-attenuated inversion recovery (hT2W-3D-FLAIR) obtained 4 hours after intravenous (IV) administration single dose gadolinium-based contrast medium (GBCM). Although maximum enhancement has been reported healthy volunteers, the timing optimal MD not reported. We investigated if that earlier or later than hours. Materials and Methods: evaluated...

10.2463/mrms.11.43 article EN Magnetic Resonance in Medical Sciences 2012-01-01

Conclusion: Our study showed that patients with atypical Meniere's disease had endolymphatic hydrops (EH) in both the cochlea and vestibule. Using an imaging method, we provide evidence is a true variant of classic disease. Objectives: The aim present was to investigate images space (cochlear vestibular disease). Methods: Sixty-four divided into two groups were enrolled this study. first group included 36 who fluctuating hearing loss without vertigo, as candidates for cochlear (CMD). second...

10.3109/00016489.2012.726374 article EN Acta Oto-Laryngologica 2012-10-29

A HYDROPS (HYbriD of Reversed image Of Positive endolymph signal and native positive perilymph Signal) image, created by subtracting a from after intravenous injection single-dose gadodiamide, has been reported to facilitate recognition endolymphatic hydrops. To further increase the contrast-to-noise ratio (CNR) images, we multiplied T2-weighted MR cisternographic onto image. Ten patients with suspected Ménière's disease were included. The average CNR generated images increased more than 200...

10.2463/mrms.2012-0027 article EN Magnetic Resonance in Medical Sciences 2013-01-01

Cell migration plays a critical role in biological processes such as embryonic development, wound healing, cancer metastasis, and immune response. While molecular mechanisms regulating cell movement are well-studied, bridging the...

10.1039/d4nr05161k article EN Nanoscale 2025-01-01

Endolymphatic hydrops (EH) in Ménière's disease is currently evaluated by 3-dimensional (3D)-real inversion recovery (IR) sequence after intratympanic (IT) administration of gadolinium (Gd) or heavily T2-weighted (hT2W)-3D-fluid-attenuated IR (FLAIR) intravenous (IV) injection Gd. Unilateral IT usually performed. We employed a method which we simultaneously administered contrast into one ear intravenously (IV side) and the other both intratympanically (IT + IV to evaluate EH 10 patients with...

10.2463/mrms.2013-0061 article EN Magnetic Resonance in Medical Sciences 2014-01-01

Conclusion: Using magnetic resonance imaging (MRI), endolymphatic hydrops could be visualized on both sides after intratympanic (IT) injection of gadolinium contrast agents (Gd) in one symptomatic ear and subsequent intravenous (IV) Gd injection. The MRI revealed a difference intracochlear distribution between the IT side contralateral IV side. Objectives: Although method allows greater enhancement perilymph, many patients feel reluctance receiving asymptomatic ears. We attempted to evaluate...

10.3109/00016489.2012.753640 article EN Acta Oto-Laryngologica 2013-01-07

To visualize endolymph, perilymph, and bone separately in a single image after intravenous injection of single-dose gadodiamide, we generated HYDROPS2 (subtraction MR cisternography from heavily T(2)-weighted 3-dimensional fluid-attenuated inversion recovery image) 12 patients with suspected Ménière's disease. The contrast-to-noise ratio endo- perilymph did not differ significantly between the previously reported HYDROPS (hybrid reversed positive endolymph signal native Signal) images, scan...

10.2463/mrms.11.303 article EN Magnetic Resonance in Medical Sciences 2012-01-01

We compared diffusion-weighted imaging (DWI) with readout-segmented multi-shot echo-planar (rs-EPI) and single-shot EPI, both using unidirectional motion-probing gradient, in 10 patients for visualization of the anatomical structures brainstem. DWI by rs-EPI was significantly better than EPI visualizing medial longitudinal fasciculus, lateral lemniscus, corticospinal tract, seventh/eighth cranial nerves offered less distortion

10.2463/mrms.10.269 article EN Magnetic Resonance in Medical Sciences 2011-01-01

Fluid-attenuated inversion recovery (FLAIR) has been reported more sensitive than T(1)-weighted images in detecting low concentration gadolinium-based contrast media (GBCM) fluid, and heavily T(2)-weighted (hT(2)W) 3-dimensional (3D) FLAIR recently even conventional 3D FLAIR. We investigated whether high signal of the anterior eye segment (AES) subarachnoid space (SAS) various locations as well cerebrospinal fluid (CSF) cisterns ventricles can be detected on hT(2)W obtained 4 hours after...

10.2463/mrms.10.193 article EN Magnetic Resonance in Medical Sciences 2011-01-01

Purpose: We developed semi-quantitative methods to measure endolymphatic size on images obtained 4 hours after intravenous administration of single-dose gadolinium-based contrast medium (IV-SD-GBCM) and found little variation in results between observers. used the endolymph healthy volunteers at various times IV-SD-GBCM attempted determine optimal timing for evaluation.Methods: In 8 male volunteers, we heavily T2-weighted 3-dimensional fluid-attenuated inversion recovery (hT2W-3D-FLAIR) 1.5,...

10.2463/mrms.2013-0080 article EN Magnetic Resonance in Medical Sciences 2014-01-01

To evaluate whether neuropathic pain affects autonomic nervous activities, we investigated daily change in cardiovascular parameters and plasma norepinephrine (NE) free-moving rats after chronic constriction injury (CCI) on the sciatic nerve. Arterial blood pressure (BP), heart rate (HR), power spectrum of pulse interval variability were analyzed. Daily motor activity nociceptive behavior was also measured from some CCI rats. In others, NE samples quantified spontaneous evaluated by...

10.1016/j.pain.2007.05.020 article EN Pain 2007-07-05

We explored normal diameter values of the cochlear (CN) and facial (FN) nerves on 3-dimensional constructive interference in steady state (3D-CISS) using a 3-tesla magnetic resonance (MR) imaging scanner.A total 142 patients underwent MR inner ear at 3T. retrospectively analyzed data from 172 ears. All ears had hearing no history ipsilateral palsy. Parasagittal images 0.5-mm thickness perpendicular to internal auditory canal were reconstructed 0.4-mm thick axial 3D-CISS for all Two...

10.2463/mrms.2013-0004 article EN Magnetic Resonance in Medical Sciences 2013-01-01

Objectives To compare the incidence of surgical site infections (SSI) between robot‐assisted and open radical cystectomies investigate risk factors for SSI after cystectomies. Methods Consecutive patients who underwent cystectomy July 2008 December 2022 were retrospectively reviewed. The prevalence characteristics compared, investigated using propensity score matching. Results This study enrolled 231 (open: 145, robot‐assisted: 86). In group, urinary diversion was performed an intracorporeal...

10.1111/iju.15382 article EN cc-by-nc-nd International Journal of Urology 2024-01-03
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