A5039612014- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Lung Cancer Diagnosis and Treatment
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Medical Imaging and Pathology Studies
- Tracheal and airway disorders
- Respiratory and Cough-Related Research
- Pediatric health and respiratory diseases
- Palliative Care and End-of-Life Issues
- Cannabis and Cannabinoid Research
- Airway Management and Intubation Techniques
- Pulmonary Hypertension Research and Treatments
- Cardiac tumors and thrombi
- Neuroinflammation and Neurodegeneration Mechanisms
- Pleural and Pulmonary Diseases
- Heme Oxygenase-1 and Carbon Monoxide
- Cardiac Structural Anomalies and Repair
- Pneumothorax, Barotrauma, Emphysema
- Dysphagia Assessment and Management
- Lymphatic Disorders and Treatments
- Healthcare Decision-Making and Restraints
- Respiratory viral infections research
- Lung Cancer Research Studies
- Management of metastatic bone disease
- Medical Device Sterilization and Disinfection
- Vascular Malformations and Hemangiomas
Sparsh Hospital
2023-2024
Apollo Hospitals
2017-2020
Apollo Hospitals
2016-2020
Louisiana State University
2018
Apollo Hospitals
2017
Albert Einstein College of Medicine
2010-2011
Montefiore Medical Center
2010-2011
Fortis Hospital
2010
Long Island Jewish Medical Center
2003-2006
North Shore University Hospital
2004-2006
End-of-life care (EOLC) exemplifies the joint mission of intensive and palliative (PC) in their human-centeredness.The explosion technological advances medicine must be balanced with culture holistic care.Inevitably, it brings together science art full expression.High-quality EOLC ICU is grounded evidence, ethical principles, professionalism within framework Law.Expert professional statements over last two decades India were developed while law was evolving.Recent landmark Supreme Court...
Background Head and neck cancers (HNCs) encompass a group of malignancies that arise in the mucosal surfaces oral cavity, pharynx, larynx, other related structures. Advances imaging modalities such as positron emission tomography-computed tomography (PET-CT) magnetic resonance (MRI) have improved tumor detection staging, aiding personalized treatment approaches. PET-CT is used to diagnose stage various cancers. Interpretation masses can be quite challenging, particularly context prior...
Abstract Occurrence of macrophage apoptosis has been implicated for the altered immune function found in an opiate milieu. In present study, we evaluated role oxidative stress morphine-induced apoptosis. Morphine promoted macrophages. This effect morphine was associated with production superoxide and nitric oxide (NO). Antioxidants provided protection against injury. addition, diphenyleneiodonium chloride, inhibitor reduced nicotinamide adenine dinucleotide phosphate (NADPH) oxidase...
Opiate addiction has been reported to contribute the progression of renal injury. In addition, opiate is a major risk factor for development human immunodeficiency virus-associated nephropathy. present study, we evaluated effects morphine, an active metabolite heroin, on glomerular epithelial cell (GEC) growth and involved molecular mechanism. At lower concentrations, morphine promoted GEC proliferation; however, at higher triggered apoptosis. Antioxidants inhibited morphine-induced...
Recently, there has been interest in the sensation of irritation that precedes motor act coughing, which termed urge-to-cough (UTC). The aim this study was to perform largest evaluation date UTC threshold (C(u)) a healthy population. specific aims were investigate relationship between C(u) and cough reflex sensitivity, evaluate gender differences assess reproducibility measurements C(u).Standard capsaicin challenge methodology employed measure sensitivity 100 adult non-smokers (50 females)...
Bone metastases are a common feature of many cancers and patients with previous history cancer may present bony symptoms to different specialties. It is, however, easy mistakenly diagnose secondary bone in who have abnormal imaging, when the cause imaging results is benign disease. In this review, diagnostic mistakes described examples both malignant The relative risk developing discussed, as well rationale therapies for proven metastases, such radiotherapy, bisphosphonate therapy,...
Prolonged air leak (PAL) is a life-threatening condition that can present either as bronchopleural fistula, or alveolar-pleural fistula (APF). Although numerous bronchoscopic treatments are described, they expensive, not widely available in the developing world have limited success. We describe our experience with novel customized endobronchial silicone blocker (CESB) for PAL treatment.This retrospective study of patients who underwent CESB placement. The was localized using balloon...
During the times of ongoing COVID pandemic, aerosol-generating procedures such as bronchoscopy have potential transmission severe acute respiratory syndrome coronavirus 2 to healthcare workers. The decision perform during pandemic should be taken judiciously. Over years, indications for in clinical practice expanded. Experts at Indian Association Bronchology perceived need develop a concise statement that would assist bronchoscopist performing safely. current Consensus Statement provides...
Conventional transbronchial needle aspiration (C-TBNA) is the originally described method for sampling mediastinal lymph nodes (MLN). After advent of endobronchial ultrasound, practice and reports C-TBNA have dwindled. We report a large series from Indian subcontinent, highlighting aspects such as pathological spectrum, yield complications, reiterating its relevance in MLN sampling.The study population included 400 consecutive patients over 6.8 years who had done ≥1 cm size. was using 19-G...
Terminal extubation (TE) and weaning have long been suggested as a modality of intervention when the continuation mechanical ventilation is not expected to achieve its therapeutic aim merely prolonging dying process.The decision, however, complex considering limited evidence regarding best practices often defied due inherent ethical, legal, medical dilemmas.The article attempts brief overview available literature on this subject discusses feasibility in Indian intensive care units (ICUs).
<b>Introduction:</b> PH is common in the sicker subsets of ILD. ILD transbronchial cryobiopsy (ILD-C) guidelines (Hetzel 2018, Dhooria et al 2019) mention [echocardiographic pulmonary artery pressure (PASP) > 40mmHg] as a relative contraindication (RC) due to risk bleeding and worsening hypoxemia. These recommendations are extrapolated from surgical sampling. <b>Aim:</b> We analysed ILD-C high-PH (PASP 40mmHg) real world situations, role pre-optimization facilitating this group, otherwise...
<b>Introduction:</b> ILD transbronchial cryobiopsy (ILD-C) guidelines (Hetzel 2018, Dhooria et al 2019) mention FVC< 50% as a relative contraindication (expert opinion), due to an increased risk of complications. <b>Aim:</b> Assess the validity these safety recommendations in real world situations, with aim assessing if sicker spectrum patients can safely undergo ILD-C. <b>Methods:</b> Retrospective review ILD-C done predicted, evaluating complications such pneumothorax(PTX), bleeding,...
Objective Massive hemoptysis (MH) has a high mortality rate. Therapeutic options include bronchoscopy for endobronchial lesions, bronchial artery embolization (BAE), and emergency surgery. Scant exist patients who are not candidates these modalities. Culprit segment occlusion is an option to prevent “spillover flooding → hypoxia.” Applying this concept, we describe case series of MH control using novel bronchoscopically inserted customized silicone blocker (CESB). We analyzed the safety...
<b>Background:</b> TBLC stands validated against surgical lung biopsy (SLB) in pathological diagnosis of ILD. complications are pneumothorax (PTX), bleeding and hypoxemia. Most ILD patients elderly with multiple comorbidities which may increase risk TBLC. Multiple guidelines on has not addressed the issue safety association comorbidities. <b>Aims & Objectives:</b> To study impact various safety/complications <b>Materials Methods:</b> The included consecutive undergoing Demographic...
Objective Bleeding is one of the main complications transbronchial lung biopsy (TBBx) more so with conditions such as azotaemia and coagulopathy. Baseline hypoxia worsens consequences TBBx bleeding can lead to escalation care. In our experience, performed through a guide sheath (GS) using it an extended working channel (EWC) helps minimize risk. We hypothesized that EWC produces tamponade effect in close vicinity site, both reducing risk restricting smaller segment. this study, we assessed...
Tuberculosis (TB), true to its description as the “Captain of men death,” is now an uncontrolled epidemic global proportions. Inherent controlling this looming threat, a high-end diagnostic and therapeutic approach, with conventional tools, out box approaches. The approach TB has seen accelerated development in attempt tackle resistance. On front, progress slow, beyond chemotherapy occasional surgery, hardly any approaches have been described. With advent newer bronchoscopic techniques such...
The Montgomery T‐tube (MTT) is a useful tool for post‐tracheostomy tracheal stenosis. However, MTTs can get blocked. We present case series of life‐threatening MTT blockage, wherein split‐function option was implemented, which customized silicone Dumon stent above the tracheostomy to maintain both airway and phonation. This tracheostomy–customized combination serves same function as an MTT, with greater margin safety due easy suctioning capacity tracheostomy. With fenestrated above, speech...