A5103106790- Peripheral Artery Disease Management
- Diabetic Foot Ulcer Assessment and Management
- Lymphatic System and Diseases
- Musculoskeletal pain and rehabilitation
- Diagnosis and Treatment of Venous Diseases
- Sarcoma Diagnosis and Treatment
- Bone Tumor Diagnosis and Treatments
- Musculoskeletal synovial abnormalities and treatments
- Osteoarthritis Treatment and Mechanisms
- Antiplatelet Therapy and Cardiovascular Diseases
- Immune cells in cancer
- Myeloproliferative Neoplasms: Diagnosis and Treatment
- Autophagy in Disease and Therapy
- Total Knee Arthroplasty Outcomes
- Orthopedic Infections and Treatments
- Aortic Thrombus and Embolism
- Esophageal Cancer Research and Treatment
- Multiple Myeloma Research and Treatments
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Muscle and Compartmental Disorders
- Orthopaedic implants and arthroplasty
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Inflammasome and immune disorders
- Biochemical and Molecular Research
- Lipoproteins and Cardiovascular Health
Second Affiliated Hospital of Zhejiang University
1996-2023
Zhejiang University Medical College Affiliated Stomatological Hospital
2023
Nanjing Medical University
2023
Zhejiang University
2018-2022
Zhejiang Lab
2022
University Gastroenterology
2018
Liaocheng People's Hospital
2018
Taishan Medical University
2018
Northwestern University
2011-2014
Hanalei Watershed Hui
2012
Neither supervised treadmill exercise nor strength training for patients with peripheral arterial disease (PAD) without intermittent claudication have been established as beneficial.
Clinical practice guidelines state there is insufficient evidence to support advising patients with peripheral artery disease (PAD) participate in a home-based walking exercise program.To determine whether program that uses group-mediated cognitive behavioral intervention, incorporating both group and self-regulatory skills, can improve functional performance compared health education control PAD without intermittent claudication.Randomized controlled clinical trial of 194 PAD, including...
Pyroptosis has been reported to improve the immunosuppressive tumor microenvironment and may be a strategy enhance osteosarcoma treatment. The extent which modulation of mitochondria could induce pyroptosis immunotherapy not characterized. We synthesized mitochondria-targeting polymer micelle (OPDEA-PDCA), in poly[2-(N-oxide-N,N-diethylamino)ethyl methacrylate] (OPDEA) was used target conjugated dichloroacetate (DCA) inhibit pyruvate dehydrogenase kinase 1 (PDHK1). This conjugate induced...
Osteosarcoma is a primary malignant bone tumor, most prevalent in children and adolescents, usually highly aggressive eventually lethal. Despite multimodal therapies, there no effective approach to treat this disease. In study, we observed the biological response of osteosarcoma cells two kinds hydroxyapatite nanoparticles (Nano HA), NanoHA-S NanoHA-L. These nanospheres have same crystallinity (phase) morphology, but they differ size. Cells treated with Nano HA were inhibited mainly led...
PAD is a disabling, chronic condition of the lower extremities that affects approximately 8 million people in United States. The purpose this study was to determine whether an innovative home-based walking exercise program for patients with peripheral artery disease (PAD) improves self-efficacy walking, desire physical competence, satisfaction functioning, social and acceptance related pain discomfort. design 6-month randomized controlled clinical trial 194 PAD. Participants were 1 2...
Objectives To determine whether poor lower extremity nerve function is associated with less‐favorable calf muscle characteristics and greater functional impairment in people without peripheral arterial disease ( PAD ). Design Cross‐sectional. Setting Three C hicago‐area medical centers. Participants Four hundred thirteen participants (ankle‐brachial index ABI ) < 0.90) 255 without. Measurements Electrodiagnostic testing of the peroneal was performed. Calf cross‐sectional area percentage...
Among 320 patients with lower extremity peripheral artery disease (PAD) and low-density lipoprotein-cholesterol (LDL-C) levels > 70 mg/dl, we determined whether male sex, higher education, greater self-efficacy for willingness to request therapy from one’s physician were associated increases in LDL-C-lowering medication achievement of an LDL-C level < mg/dl at 1-year follow-up. Participants enrolled a randomized controlled clinical trial determine telephone counseling intervention can...
Esophageal stricture is a debilitating condition that negatively impacts patients' quality of life after undergoing endoscopic mucosal resection (EMR). Despite its significance, this disease remains underexplored due to the lack stable animal model. Under direct visualization with choledochoscopy, we retrogradely damaged esophageal layer through gastrostomy create rat model stricture. The development histological defects in was assessed over 2-week period induction. Then models were...
The clinical implications of low vitamin D in peripheral artery disease (PAD) are unknown. We hypothesized that among individuals with PAD, lower levels 25-hydroxyvitamin would be associated poorer functional performance, more adverse calf muscle characteristics, and nerve function. Participants were 402 men women PAD who underwent measurement (DiaSorin radioimmunoassay) along 6-minute walk testing, walking velocity at usual fastest pace, computed tomography-measured density, conduction...
Individuals with peripheral arterial disease (PAD) have a nearly two-fold increased risk of all-cause and cardiovascular mortality compared to those without PAD. This pilot study determined whether metabolomic profiling can accurately identify patients PAD who are at near-term mortality.We completed case-control using (1)H NMR plasma from 20 decedents PAD, critical limb ischemia, had blood drawn within 8 months prior death (index draw) 10 28 (preindex draw). Twenty-one participants survived...
The current study aimedto screen for possible factors which affect prognosis of chondrosarcoma.Thirty seven cases were selected and analyzed statistically. patients received surgical treatment at our hospital between December 2005 March 2008. All them had complete follow-up data. survival rates calculated by univariate analysis using the Kaplan-Meier method tested Log-rank. χ2 or Fisher exact tests carried out numeration significant indexes after then multivariate COX regression model. Based...
Dislocation of the hip remains a major complication after periacetabular tumour resection and endoprosthetic reconstruction. The position acetabular component is an important modifiable factor for surgeons in determining risk postoperative dislocation. We investigated significance horizontal, vertical, sagittal displacement centre rotation (COR) on dislocation using CT-based 3D model, as well other potential factors dislocation.A total 122 patients who underwent reconstruction following...
The aim of the study was to evaluate efficacy and safety umbilical cord blood stem cells (USCs) transplantation combined with routine supportive therapy (RST) for liver cirrhosis (LC).Clinical trials involved in this research were searched from Web Science, PubMed, EMBASE, Cochrane Library, Wanfang CNKI database. Treatment effects, quality life (QoL), adverse events other outcome measures extracted evaluated.A total 10 including 616 LC patients study. Based on our analysis, function...
OBJECTIVES:To investigate the diagnosis and treatment of tibial intercondylar chondroblastoma.METHODS: We retrospectively analyzed 12 patients with chondroblastoma admitted to orthopedics department from May 2011 February 2016; among them were 4 males 3 females aged 10-19 years, an average age 15.7 years.Tibial was on left right side in 7 5 cases, respectively.The preoperative Lysholm score knee joint 68 (42-87).A posteromedial approach applied all cases.The incisions approximately 5-8 cm...
OBJECTIVES. It is currently unknown whether high-risk atherosclerotic plaque develops simultaneously in multiple arterial beds or it an isolated phenomenon. We used direct imaging with magnetic resonance (MRI) participants lower extremity peripheral disease (PAD) to determine individuals lipid rich necrotic core (LRNC) the femoral arteries have a higher prevalence of LRNC carotid than without arteries. METHODS AND RESULTS. Twenty-four PAD underwent both their and superficial Four (16.7%) had...
Among plasma cell disorders, solitary plasmacytoma (solitary-plasmacytoma of bone, SPB and extramedullary plasmacytoma, EMP) is rare as compared with mulitiple myeloma (MM). Furthermore, the relationship between MM remains unclear. Between 1960 1994, 24 patients 20 EMP were treated. The criteria for diagonosis were: (1) No evidence other lesions based on clinical radiologic examinations; (2) Biopsy a neoplasm; (3) Bone marrow biopsy specimen negative findings (less than 10% cell); (4)...