- Crystallization and Solubility Studies
- X-ray Diffraction in Crystallography
- Metabolomics and Mass Spectrometry Studies
- Neurological Disease Mechanisms and Treatments
- Medicinal Plant Pharmacodynamics Research
- Traditional Chinese Medicine Studies
- Botanical Research and Chemistry
- CO2 Sequestration and Geologic Interactions
- Electrochemical sensors and biosensors
- Diabetic Foot Ulcer Assessment and Management
- Chromatography in Natural Products
- Medical Research and Treatments
- Ginger and Zingiberaceae research
- Garlic and Onion Studies
- Burn Injury Management and Outcomes
- Hydrogen's biological and therapeutic effects
- Stress Responses and Cortisol
- Dye analysis and toxicity
- Gas Sensing Nanomaterials and Sensors
- Ionic liquids properties and applications
- Advanced biosensing and bioanalysis techniques
- Liver Disease Diagnosis and Treatment
- Gut microbiota and health
- Antioxidants, Aging, Portulaca oleracea
- Traditional Chinese Medicine Analysis
First Affiliated Hospital of Henan University
2017-2025
Sichuan Normal University
2024
Henan University of Traditional Chinese Medicine
2008-2023
Southwest University of Science and Technology
2023
Nankai University
2023
Yulin Normal University
2021
Henan University
2017
Shanghai University of Traditional Chinese Medicine
2012
The present study aimed to evaluate the effects of paeoniflorin on insulin resistance and hepatic steatosis induced by fructose. Male Sprague-Dawley rats were fed 20% fructose drink for eight weeks. sensitivity, serum lipid profiles, lipids contents measured. results showed that significantly decreased glucagon levels, improved sensitivity alleviated in fructose-fed rats. Moreover, enhanced phosphorylation level AMP-activated protein kinase (AMPK) B (PKB/AKT) inhibited acetyl coenzyme A...
Icariin is a prenylated flavonol glycoside isolated from Epimedium herb, and has been shown to be its main bioactive component. Recently, the antidepressant-like mechanism of icariin increasingly evaluated demonstrated. However, there are few studies that have focused on involvement phosphatidylinositol 3-kinase (PI3K)/serine-threonine protein kinase (AKT) signaling in mediating perimenopausal depression effects icariin. Perimenopausal chronic recurrent disease leads an increased risk...
The present study was envisaged to investigate the chemical constituents and intervention effects of Portulaca oleracea extract (POE) on acute alcoholic liver injury rats. composition POE detected by high performance liquid chromatography (HPLC). Sixty male Wistar rats were divided into 6 groups: Normal control (NC) group, model group (ALI), low, medium dose (25, 50, 100 mg/kg) groups bifendate (BF, 3.75 group. Each given intragastrical administration for 7 days. Alcoholic induced in...
Ilex pubescens is commonly used in traditional Chinese medicine to treat cardiovascular and cerebrovascular diseases, such as coronary artery disease stroke. However, the underlying mechanisms remain be fully elucidated. The aim of present study was investigate effects total flavonoids (IPTF) on neuroprotection potential a rat model focal cerebral ischemia/reperfusion (I/R) injury. Rats were pretreated with intragastric administration IPTF at doses 200 100 mg/kg for 5 days; middle occlusion...
To investigate the protective mechanism of verbenalin on cerebral ischemia-reperfusion injury. Middle artery occlusion in left hemisphere was induced rats by filament insertion, and rat model focal established. The high, medium low dose groups were injected tail vein corresponding drugs 10 min before reperfusion, submitted for 22 h reperfusion after operation. Mortality rate then calculated, neurological deficits scored. serum got to determine S-100β protein level, brain tissue removed...
Accumulating evidence has underscored the prognostic value of tumor-infiltrating immune cells in tumor microenvironment colon cancer (CC). In this retrospective study, based on publicly available transcriptome profiles and clinical data from Gene Expression Omnibus The Cancer Genome Atlas databases, we derived verified an activated dendritic cell (aDC)-related gene signature (aDCRS) for predicting survival outcomes chemotherapy immunotherapy response CC patients. We quantified infiltration...
The investigation into the interfacial properties between fullerene compounds and Sn-based perovskites (Sn-PVSK) holds extraordinary significance for advancing efficient stable Pb-free perovskite solar cells. This study is first theoretical exploration to examine their using Ab initio molecular dynamics (AIMD) simulations trajectory analysis methods with C60@FASnI
Three co-formers of 2-chloro-4-nitroaniline (CNA), 2,5-dihydroxybenzoic acid (DHB), and 4,4'-biphenol (DOD) were selected to prepare the co-crystal progesterone (PROG) based on crystal engineering strategies. These co-crystals successfully obtained via slow evaporation from different solutions characterized by single-crystal X-ray diffraction spectroscopy, powder diffraction, IR differential scanning calorimetry. Different binding networks observed in structures PROG. The PROG-CNA had...
Postmenopausal osteoporosis (PMOP) is a chronic bone metabolic disease, which often causes fractures and various complications, it great social economic burden, urgent to use modern research techniques elucidate the pathogenesis of PMOP. At same time, because complex physiological pathological interaction mechanism between sarcopenia, correlation has become hot topic. Ovary removal commonly used experimental method study endocrine system female animals, also best animal model In this study,...
The objective of this experiment is to investigate the effect Maozhaocao polysaccharide on thymus and spleen Immunosuppressive Model Mice.Study model mice by using cyclophosphamide, for large, medium small dose polysaccharide, Mushrooms contral group.The were treated 7d.Take pathological section.Maozhuacao can significantly increased number cortex cells in animals, nodules lymphocytes model.Conclusion: could resist atrophy model.
Homology of medicine and food is an important content in Chinese also works as the basis for guiding development compound health containing materia medica. The top products,supplements,health care prescriptions,and medicinal meals traditional herbal texts are theoretical treasures foods. With implementation National Healthy China 2030,China's major industry faces with tremendous opportunities. It necessary to develop a batch medica characteristics,in line needs country society. Domestic...