A5088150099- Vascular anomalies and interventions
- Central Venous Catheters and Hemodialysis
- Metabolism and Genetic Disorders
- Lysosomal Storage Disorders Research
- Personality Disorders and Psychopathology
- Amino Acid Enzymes and Metabolism
- Mitochondrial Function and Pathology
- Action Observation and Synchronization
- Vascular Procedures and Complications
- Bullying, Victimization, and Aggression
- Click Chemistry and Applications
- Educational and Social Studies
- ATP Synthase and ATPases Research
- Male Reproductive Health Studies
- Elder Abuse and Neglect
- Healthcare Decision-Making and Restraints
- Digital Mental Health Interventions
- Neuroscience, Education and Cognitive Function
- Biomedical Research and Pathophysiology
- Deception detection and forensic psychology
- Seismology and Earthquake Studies
- Management of metastatic bone disease
- Vascular Malformations and Hemangiomas
- Stalking, Cyberstalking, and Harassment
- Virtual Reality Applications and Impacts
Great Ormond Street Hospital for Children NHS Foundation Trust
2022-2024
University College London
2022-2024
Great Ormond Street Hospital
2022-2023
University of Verona
2021
Ospedale Garibaldi
2013-2014
Azienda Ospedaliero-Universitaria Policlinico - Vittorio Emanuele
2010-2011
The urea cycle enzyme argininosuccinate lyase (ASL) enables the clearance of neurotoxic ammonia and biosynthesis arginine. Patients with ASL deficiency present argininosuccinic aciduria, an inherited metabolic disease hyperammonemia a systemic phenotype coinciding neurocognitive impairment chronic liver disease. Here, we describe dysregulation glutathione upstream cysteine utilization in ASL-deficient patients mice using targeted metabolomics vivo positron emission tomography (PET) imaging (...
Introduction: Biotinidase deficiency (BD) is an autosomal recessive disease causing a defect in the biotin-releasing enzyme. Newborn screening (NBS) allows early diagnosis and treatment, ensuring excellent prognosis. The aim of this study was to describe our experience diagnosis, follow-up showing key strategies unsolved questions management BD patients. Methods: We analyzed data patients identified by Regional Centre for Screening Verona followed Inherited Metabolic Disease Unit Neonatal...
Abstract Argininosuccinate lyase (ASL) is a key enzyme integral to the hepatic urea cycle which required for ammonia detoxification, and citrulline-nitric oxide (NO) NO production. ASL deficient patients present with argininosuccinic aciduria (ASA), an inherited metabolic disease hyperammonaemia chronic systemic phenotype neurocognitive impairment liver disease. deficiency as model of deficiency, shows enhanced nitrosative oxidative stress. Here, we describe dysregulation glutathione...
Abstract Glycosylphosphatidylinositol anchored proteins (GPI‐APs) represent a class of molecules attached to the external leaflet plasma membrane by GPI anchor where they play important roles in numerous cellular processes including neurogenesis, cell adhesion, immune response and signalling. Within group defects, six present with clinical phenotype Hyperphosphatasia Mental Retardation Syndrome (HPMRS, Mabry Syndrome) characterized moderate severe intellectual disability, dysmorphic...
Several studies investigate empathy as the ability to understand and share a person's emotional states. Recent researches explore phenomenological peculiarity of empathy. The present work is review existing scientific literature about construct empathy, paying specific attention new methods it. Particularly, study presents form measurement: virtual reality (VR). This proposes hypothesis research, in order test possibility increase using VR subjects with diagnosis Personality Disorder...
Purpose The arteriovenous fistula (AVF) represents the gold standard for hemodialysis (HD) vascular access. In some critical cases, use of deep venous circle may represent an alternative approach and venae comitantes could be employed this purpose. Methods Sixty patients with chronic renal failure in which was used to create AVF were identified; 48 who had a direct anastomosis between brachial artery vena comitans, 42 long-term follow-up (mean 59 weeks), while six lost follow-up. Results...
This article describes the approach to atypical placement of central venous catheters (CVC) in dialysis patients with complete untreatable obstruction vessels.Five vessels underwent CT venography and digital angiography. After ultrasound-guided radioscopic-assisted cannulation internal jugular vein, permanent CVCs were placed locations: two a preliminary angioplasty was performed facilitate catheter positioning mediastinal enlarged collateral vein persistent left superior vena cava; three...
Purpose This article describes the approach to atypical placement of central venous catheters (CVC) in dialysis patients with complete untreatable obstruction vessels. Methods Five vessels underwent CT venography and digital angiography. After ultrasound-guided radioscopic-assisted cannulation internal jugular vein, permanent CVCs were placed locations: two a preliminary angioplasty was performed facilitate catheter positioning mediastinal enlarged collateral vein persistent left superior...
The scientific evidence found in the literature shows that aggression is innate humans, a reactive and proactive form. This work proposes distinction between an aggressive act predisposition to aggression, highlighting how this type of behavior normative natural child's development. Aggressiveness reaches its peak two four years old tends decrease sensibly permanently throughout life. traces genetic temperamental correlates aggressiveness, highlights relationship decision making explores...
The way individuals make choices and decisions influences their behavior life style. choice is not simply based on rational formal logic, but it's influenced by many emotional social factors. Starting from this assumption, some studies investigated the in which emotions influence decision-making processes, while others explored possibility that processes are compromised onset of psychiatric pathologies presence prefrontal cortexlesions, can induce a radical change basic preferences subject....
Continuous management of dialysis patients exposes family caregivers to significant psychophysical risks. Having demonstrated the effectiveness artificial intelligence in care and assistance processes, it was hypothesized implementation a mobile app which would detect distress these Family Caregivers order activate support actions adequate sustenance. In identify Burnout risk factors patients, 31 items were selected, from questionnaires recognized literature, submitted sample 713 subjects....
Introduction: Empathy is a multidimensional construct that incorporates two different dimensions: affective/emotional and cognitive. Recent studies have shown empathic abilities are threatened in some specific cases. In particular, psychopathy characterized by complete lack of emotional/affective empathy. As matter fact, psychopathic individuals seem to skills related cognitive The main brain regions involved in processes include anterior cingulate cortex insula. Method: A careful analysis...
Introduction: Nurses that work within prisons find themselves in conditions where management of safety comes hand with the right to receive healthcare. A difficult and complicated context assistance must be provided regardless crime committed by patient. Objective: Identify specific role skills nurses working penitentiaries institutions Materials methods: Research articles was carried out through consultation biomedical data-banks, such as Medline (PubMed) Cinahl, obtaining scientific from...