A5033955686- Emergency and Acute Care Studies
- Acute Myocardial Infarction Research
- Esophageal Cancer Research and Treatment
- Opinion Dynamics and Social Influence
- Complex Network Analysis Techniques
- Angiogenesis and VEGF in Cancer
- Cancer Research and Treatments
- Chronic Lymphocytic Leukemia Research
- Misinformation and Its Impacts
- HER2/EGFR in Cancer Research
- Immunodeficiency and Autoimmune Disorders
- Monoclonal and Polyclonal Antibodies Research
- Medical Research and Treatments
- Cancer, Hypoxia, and Metabolism
- Pain Management and Opioid Use
- Gastric Cancer Management and Outcomes
- ECG Monitoring and Analysis
- Trauma and Emergency Care Studies
- Chronic Myeloid Leukemia Treatments
- Immunotherapy and Immune Responses
- Eosinophilic Disorders and Syndromes
- Cardiac electrophysiology and arrhythmias
- Ferroptosis and cancer prognosis
- Cancer Immunotherapy and Biomarkers
- Nanowire Synthesis and Applications
South China University of Technology
2021-2024
Union Hospital
2021-2023
Huazhong University of Science and Technology
2021-2023
Southern Medical University
2021
Chinese Academy of Medical Sciences & Peking Union Medical College
2015
Yancheng Third People's Hospital
2011-2012
First People's Hospital of Kunshan
2011
Jiangsu University
2011
Soochow University
2008
Karolinska Institutet
2006-2008
Objective: This study was performed to evaluated the efficacy and safety of continuous infusional paclitaxel 5-Fu as first-line chemotherapy in patients with advanced esophageal squamous cell cancer (ESCC). Methods: A total 22 no indications for surgery radiation therapy, or recurrent were enrolled from October 2008 November 2010. All treated PTX 20 <TEX>$mg/m^2$</TEX> administered through a 16 hours intravenous infusion on days 1 3, 8 9. DDP 3.75 given 4 11, 5-FU over 24-hours 5 12 at dose...
The formation of information cocoons, driven by limited disclosure and individual preferences, has resulted in the polarization society. However, underlying mechanisms pathways to escape these cocoons remain unresolved. This article aims solve it developing an adaptive imitation process. In this process, measurement across population is based on Shannon's entropy, taking into account neighborhood information. Incorporating Dirac function formulate distribution over networks, theoretical...
Delta-like-1 (Dlk1, also Pref-1), a transmembrane and secreted protein, is member of the epidermal growth factor-like family, homologous to Notch/Delta/Serrate. We found that expression Dlk1 was up-regulated in CD34+ cells from patients with myelodysplastic syndrome (MDS) by analyzing gene profiles determined microarray. The levels mRNA frequently observed higher bone marrow mononuclear MDS confirmed real-time RT-PCR. Forced transfected K562 enhanced proliferation, affected apoptosis induced...
To evaluate the value of modified early warning score ( MEWS ) in predicting mortality critically ill patients admitted to emergency department.A prospective cohort study was conducted. Clinical data resuscitation room Peking Union Medical College Hospital from Feburary 13rd, 2014 April 20th, were collected, and their calculated based on medical records clinical outcomes followed. Incidence primary outcome 3-day secondary [ all deaths composite intensive care unit ICU transfer,...
Abstract Background Pancreatic cancer is one of the most lethal malignancies and lack treatment options makes it more deadly. Chimeric Antigen Receptor T-cell (CAR-T) immunotherapy has revolutionized made great breakthroughs in treating hematological malignancies, however its success solid cancers remains limited mainly due to tumor-specific antigens. On other hand, prolonged traditional manufacturing process poses challenges, taking 2 6 weeks impacting patient outcomes. CD276 recently...
Objective To evaluate the efficacy and security of combined recombinant human endostatin with GP chemotherapy for treatment advanced non-small-cell lung cancer (NSCLC).Methods Non- randomized concurrent control was used.32 patients were treated by as test group,40 group only received chemotherapy.The response rate (RR),the clinical benefit (CBR) time to progression (TTP) observed.Results The total RR in two groups 40.6 ％ 20.0 (x2 =3.66,P =0.07).The CBR 68.8 42.5 =4.93,P =0.034).The 5.2...
Lung adenocarcinoma (LUAD) has become the most common pathological type of lung cancer in recent years. However, molecular mechanism LUAD remains unclear. To reveal laws occurrence and development LUAD, this paper first collects 676 differentially expressed genes related to corresponding proteins encoded by genes, resulting a complex protein-protein interaction (PPI) network. The traditional analysis methods focus on gene relationships or important separately, ignoring fact that some target...
Objective To establish a practicable and balanced emergency department overcrowding (EDO) assessment system suitable for domestic application in Chinese ED setting. Methods The factors that might affect EDO were evaluated by multiple linear regression analysis. The National Emergency Department Overcrowding Scale(NEDOCS) was modified(NEDOCSBJ). database of which founded the Multidimensional Scale (MEDOS) items, including 9 objective 3 subjective screened. Simultaneously, data pairs...
Objective To evaluate the safety,feasibility and efficacy of emergency percutaneous coronary intervention(PCI)on spot in patients with acute myocardial infarction(AMI)in country hospitals by interventional cardiologists from higher-level hospitals(converse transport).Methods A total 81 AMI received PCI on other (transported doctors)from Mar 2004 to Sep 2008 our hospital.The mean age was 68.6 ± 3.6 years (36.0-83.0 years).Forty-six were male 35 female.There 56 cases anterior infarction 25...
Objective To evaluate the effect of thrombus aspiration technique in emergency percutaneous coronary intervention for patients with ST segment elevation myocardial infarction(STEMI). Methods According to digital table, 48 acute anterior infarction were randomly into 22 cases control group(routine stent implantation) and 26 observation group(thrombus then implantation). The changes TIMI grading, left ventricular ejection fraction, NT-ProBNP compared between two...