Jun Xu

ORCID: 0000-0002-2309-990X
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About
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Research Areas
  • Acute Kidney Injury Research
  • Nutrition and Health in Aging
  • Sepsis Diagnosis and Treatment
  • Pancreatic and Hepatic Oncology Research
  • Pancreatitis Pathology and Treatment
  • Liver Disease Diagnosis and Treatment
  • Clinical Nutrition and Gastroenterology
  • Liver Disease and Transplantation
  • Dialysis and Renal Disease Management
  • Diabetes Management and Research
  • Child Nutrition and Feeding Issues
  • Cardiac Arrest and Resuscitation
  • Organ Transplantation Techniques and Outcomes
  • Chronic Kidney Disease and Diabetes
  • Muscle and Compartmental Disorders
  • Antibiotic Use and Resistance
  • Nosocomial Infections in ICU
  • Amoebic Infections and Treatments
  • COVID-19 Pandemic Impacts
  • Intensive Care Unit Cognitive Disorders
  • Lymphoma Diagnosis and Treatment
  • Trauma and Emergency Care Studies
  • Acute Lymphoblastic Leukemia research
  • COVID-19 and healthcare impacts
  • Mesenchymal stem cell research

First Hospital of Shanxi Medical University
2024

Shanxi Medical University
2024

Peking Union Medical College Hospital
2023

Chinese Academy of Medical Sciences & Peking Union Medical College
2023

Zhejiang University
2019-2022

University of Hong Kong
2012-2022

University of Chinese Academy of Sciences
2019-2021

Shanghai Sixth People's Hospital
2021

Taihe Hospital
2020

First Affiliated Hospital Zhejiang University
2020

Extubation failure is a complex and ongoing problem in the intensive care unit (ICU). It refers to patients who require re-intubation after extubation (namely disconnection from mechanical ventilation). In these patients, leads severe risks associated with increased mortalities, longer stay ICU also higher health costs. Many studies have been proposed analyze of identify possible factors or indices that may predict failure. However, used small number for limited their features several vital...

10.1109/access.2019.2946980 article EN cc-by IEEE Access 2019-01-01

Abstract Currently, little information is available to stratify the risks and predict acute kidney injury (AKI)-associated death. In this present cross-sectional study, a novel scoring model was established probability of death within 90 days in patients with AKI diagnosis. For establishment predictive model, clinical data 1169 hospitalized were retrospectively collected, 731 them as first group analyzed by method multivariate logistic regression analysis create further patient Then 438...

10.1038/s41598-017-08440-w article EN cc-by Scientific Reports 2017-08-07

Background: Due to the novel coronavirus epidemic, medical workers are under immense psychological pressure. As such, East Campus of Shanghai Sixth People's Hospital actively adopted Symptoms Checklist 90 (SCL-90) evaluate mental health hospital staff before and after intervention from Employee Assistance Program (EAP). Methods: Medical were recruited for this study. Psychological evaluations conducted using SCL-90, with a score >160 regarded as positive result, or in other words, an...

10.3389/fpubh.2021.649157 article EN cc-by Frontiers in Public Health 2021-07-28

The majority of patients with COVID-19 showed mild symptoms. However, approximately 5% them were critically ill and require intensive care unit admission for advanced life supports. Patients in the high risk venous thromboembolism hemorrhage due to immobility anticoagulants used during aim study was report incidence treatments two complications such patients.Patients (Group 1) community-acquired pneumonia 2) that required enrolled this retrospective study. Their demographics, laboratory...

10.1177/20503121211020167 article EN cc-by-nc SAGE Open Medicine 2021-01-01

Objective: To evaluate the effects of Huai Qi Huang (HQH) granules on primary glomerulonephritis patients, and to discuss its possible mechanisms. Method: Sixteen patients diagnosed with glomerular disease between December 2011 2012 were enrolled. Their blood urine samples collected at day 0 (the baseline levels), 30, 90 receiving HQH orally. Levels creatinine cystatin C (Cys-C) in serum urine, total protein albumin measured by automatic biochemical analyzer. Neutrophil gelatinase-associated...

10.3109/0886022x.2014.952746 article EN Renal Failure 2014-09-23

Novel immunotherapy is one of the options for advanced biliary tract cancer (BTC) patients who are traditionally intolerant to chemotherapy. However, clinical evidence single with pembrolizumab or nivolumab limited. The present study assessed safety and efficiency anti-PD-1 antibody, camrelizumab, as monotherapy in unresectable recurrent BTC.A retrospective evaluation was conducted among 4 BTC, including 2 intrahepatic cholangiocellular carcinoma (ICC), extrahepatic bile duct cancer,...

10.1177/1533033820979703 article EN cc-by-nc Technology in Cancer Research & Treatment 2020-01-01

Background: Our previous study revealled amplified hazardous effects of macrosteatosis (MaS) on graft failure (GF) in recipients with severe liver damage short post-operative days, vague mechanism inside. Aim: We aimed to uncover the molecular donor MaS GF, and construct predictive model monitor post-transplant prognosis based "omics" perspective. Methods: Ultra-performance liquid chromatography coupled mass spectrometry metabolomic analysis was performed allograft tissues from 82 patients...

10.3389/fcell.2020.00826 article EN cc-by Frontiers in Cell and Developmental Biology 2020-08-28

To evaluate the value of modified early warning score ( MEWS ) in predicting mortality critically ill patients admitted to emergency department.A prospective cohort study was conducted. Clinical data resuscitation room Peking Union Medical College Hospital from Feburary 13rd, 2014 April 20th, were collected, and their calculated based on medical records clinical outcomes followed. Incidence primary outcome 3-day secondary [ all deaths composite intensive care unit ICU transfer,...

10.3760/cma.j.issn.2095-4352.2015.08.014 article EN PubMed 2015-08-01

Background Non-alcoholic fatty liver disease (NAFLD) and chronic kidney (CKD) are both closely related to dyslipidemia. However, the relationship between dyslipidemia in patients with NAFLD CKD is not yet clear. The non-high-density lipoprotein cholesterol high-density ratio (NHHR) an innovative comprehensive lipid index. purpose of this study was investigate correlation NHHR risk or without fibrosis. Methods This used data from National Health Nutrition Examination Survey (NHANES) 2017 2020...

10.3389/fnut.2024.1501494 article EN cc-by Frontiers in Nutrition 2024-12-24

Data on incidence rates of myeloid malignancies for subtypes based the World Health Organization (WHO) classification are lacking in Asian populations. We compared age-adjusted 27 malignancy WHO-defined Hong Kong (HK) (2014–2016) with those and white individuals living United States (U.S.) (2010–2016). Except overall acute leukemia (AML) (2.23 cases per 100,000) myeloproliferative neoplasms (MPNs) (2.10 100,000), all were <1 case 100,000 person-years HK. Overall AML, myelodysplastic syndrome...

10.1080/10428194.2022.2045593 article EN Leukemia & lymphoma/Leukemia and lymphoma 2022-04-12

&lt;p class="Abstract"&gt;We expounded the effect of intravenous arginine on healing human skin graft donor sites. This randomized study was double blind and controlled by placebos from October 2012 to May 2015. Nine patients were selected into group 10 control group. There no significance in age, weight, BMI, CRP, albumin total plasma protein groups. Angiogenesis, re-epithelialization neutrophil influx wound measured. The concentrations amino acid measured evaluate our intervention. In...

10.3329/bjp.v10i4.23850 article EN cc-by Bangladesh Journal of Pharmacology 2015-09-18

Objective To quantify the concentration of peripheral blood plasma neutrophil gelatinase-associated lipocalin (NGAL) in patients with acute pancreatitis (AP) and to explore its value assessment severity AP.Methods From June 2011 March 2012,83 AP were selected,among those 43 cases mild (MAP) 40 severe (SAP).The control group included 30 healthy individuals.The controls was collected,and isolated after centrifuged.The NGAL detected by enzyme-linked immunosorbent assay (ELISA).The t-test...

10.3760/cma.j.issn.0254-1432.2014.03.008 article EN Zhonghua xiaohua zazhi 2014-03-15

Abstract Background: Metabolic alkalosis has raised concerns in patients receiving continuous renal replacement therapy (CRRT) via regional citrate anticoagulation (RCA). This study searched for alkalosis-related factors and mechanisms. Measurements: We conducted a retrospective cross-sectional of who received CRRT at least 12 hours with RCA an emergency department tertiary hospital between April 2017 2020. Main Results: The 59 meeting the inclusion criteria were 49% male, mean age 55 ± 18...

10.21203/rs.3.rs-3414913/v1 preprint EN cc-by Research Square (Research Square) 2023-10-19

Abstract The pattern recognition pathway plays an important role in infection and immune responses, previous studies have suggested association between genetic variation innate immunity genes non-Hodgkin lymphoma (NHL). We evaluated NHL risk associated with the common using data from a case-control study of conducted Connecticut women. Single nucleotide polymorphisms (SNPs) 27 were genotyped 432 Caucasian incident cases 494 frequency-matched controls. Unconditional logistic regression was...

10.1158/1538-7445.am2012-2641 article EN Cancer Research 2012-04-01

To investigate the efficiency of closed tracheal suction system (CTSS) using novel splash-proof ventilator circuit component on ventilator-associated pneumonia (VAP) and colonization multiple-drug resistant bacteria (MDR) in patients undergoing mechanical ventilation (MV) prevention.A prospective single-blinded randomized parallel controlled intervention study was conducted. 330 severe admitted to intensive care unit (ICU) First Hospital Jiaxing from January 2014 May 2016 were enrolled, they...

10.3760/cma.j.issn.2095-4352.2017.01.004 article EN PubMed 2017-01-01

Objective To observe the clinical effects of transitional care intervention on patients with diabetic foot ulcer (DFU) , so as to provide nursing evidence for clinical. Methods The literatures randomized controlled trials (RCT) were searched electronically in national and international medical databases from database created 31st January 2017. The modified Jadad scale was used evaluate methodological quality. Rev Man 5.3.1 software Meta-analysis. Results A total 16 RCTs enrolled...

10.3760/cma.j.issn.1674-2907.2017.36.008 article EN Zhonghua xiandai huli zazhi 2017-12-26
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