Kuan Shion Ong

ORCID: 0000-0003-0494-9013
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Research Areas
  • Genomics and Phylogenetic Studies
  • Microbial Community Ecology and Physiology
  • Bacteriophages and microbial interactions
  • Bacterial biofilms and quorum sensing
  • Plant Pathogenic Bacteria Studies
  • Enzyme Production and Characterization
  • Identification and Quantification in Food
  • Anaerobic Digestion and Biogas Production
  • Gut microbiota and health
  • Global Health Workforce Issues
  • Medicinal Plant Research
  • Plant-Microbe Interactions and Immunity
  • Plant Pathogens and Fungal Diseases
  • Curcumin's Biomedical Applications
  • Probiotics and Fermented Foods
  • Parasites and Host Interactions
  • Microbial Natural Products and Biosynthesis
  • Ginger and Zingiberaceae research
  • Parasitic infections in humans and animals
  • Phytochemistry and Bioactivity Studies
  • Animal Behavior and Reproduction
  • Essential Oils and Antimicrobial Activity
  • Zoonotic diseases and public health
  • Antimicrobial agents and applications
  • Epigenetics and DNA Methylation

University of California, Santa Cruz
2024

Monash University Malaysia
2014-2021

Abstract No studies have investigated the influence of ethnicity in a multi-ethnic middle-income country with long-standing history co-habitation. Stool samples from 214 Malaysian community members (46 Malay, 65 Chinese, 49 Indian, and 54 Jakun) were collected. The gut microbiota participants was using 16S amplicon sequencing. Ethnicity exhibited largest effect size across (PERMANOVA Pseudo-F = 4.24, R 2 0.06, p 0.001). Notably, on retained even after controlling for all demographic, dietary...

10.1038/s41598-021-82311-3 article EN cc-by Scientific Reports 2021-01-29

The increase in prevalence of antimicrobial-resistant bacteria (ARB) is currently a serious threat, thus there need for new antimicrobial compounds to combat infections caused by these ARB. An antimicrobial-producing bacterium, Burkholderia paludis was recently isolated and able produce type siderophore with properties, later identified as pyochelin. chelating ability pyochelin has been well-characterized but not its characteristics. It found that had MIC values (MBC values) 3.13 µg/mL (6.26...

10.1016/j.jare.2017.05.007 article EN cc-by-nc-nd Journal of Advanced Research 2017-05-21

A novel Gram negative rod-shaped bacterium, designated strain MSh1T, was isolated from Southeast Pahang tropical peat swamp forest soil in Malaysia and characterized using a polyphasic taxonomy approach. The predominant cellular fatty acids (>10.0%) were C16:0 (31.7%), C17:0 cyclo (26.6%) C19:0 w8c (16.1%). polar lipids detected phosphatidylglycerol, phosphatidylethanolamine diphosphatidylglycerol. ubiquinone Q-8. This revealed that MSh1T belongs to the genus Burkholderia. type can be...

10.3389/fmicb.2016.02046 article EN cc-by Frontiers in Microbiology 2016-12-21

Emergence of antimicrobial resistance coupled with the slowdown in discovery new compounds points to serious consequences for human health. Therefore, scientists are looking from unique and understudied ecosystems such as tropical peat swamp forests. Over course isolating producing bacteria North Selangor forest, Malaysia, a Gram variable, rod shaped, endospore forming, facultative anaerobic novel strain MSt1(T) that exerts potent broad spectrum activity was isolated. Phylogenetic analysis...

10.3389/fmicb.2016.00219 article EN cc-by Frontiers in Microbiology 2016-03-01

The aim of this study was to investigate the antimicrobial activities Etlingera pubescens, and isolate identify compound.

10.1111/jam.14287 article EN Journal of Applied Microbiology 2019-04-21

Abstract Maternal age can influence reproductive success and offspring fitness, but the timing, magnitude direction of those impacts are not well understood. Evolutionary theory predicts that selection on fertility senescence is stronger than maternal effect senescence, therefore, rate will be faster senescence. We used a 36‐year study northern elephant seals ( Mirounga angustirostris ) to investigate Our dataset included 103,746 sightings 1203 known‐age female seals. hypothesized (maternal...

10.1111/1365-2656.14226 article EN cc-by-nc Journal of Animal Ecology 2024-11-19

The potential of Dicranopteris linearis leaves' extract and its bioactive components were investigated for the first time disrupting ability against Staphylococcus aureus biofilms.The leaves D. subjected to sonication-assisted extraction using hexane (HEX), dichloromethane, ethyl acetate methanol (MeOH). It was found that only MeOH fraction exhibited antimicrobial activity broth microdilution assay; while all four fractions do not exhibit biofilm inhibition S. aureusATCC 6538P, 43300, 33591...

10.1111/jam.13578 article EN Journal of Applied Microbiology 2017-09-04

The full plethora of environmental bacteria is often poorly represented in vitro as the majority remain difficult, if not impossible, to culture under standard laboratory settings. These require native conditions for formation cell masses that collectively have higher chances survival. With that, a 3D-printed version isolation chip (iChip) was used cultivate from tropical peat swamp situ prior growth and maintenance vitro. Briefly, plates made either acrylonitrile butadiene styrene (ABS),...

10.1039/d1lc00723h article EN Lab on a Chip 2021-12-22

Aims:The aims of this study were to isolate and characterize antimicrobial producing bacteria from tropical peat swamp forest soils.Methodology results: Bacteria isolated soil screened for properties via agar overlay assay.Broth microdilution was performed using crude-cell free supernatant (CCFS) determine the minimum inhibitory concentration (MIC).One selected due its broad spectrum activity identified as Burkholderia spp. with a maximum identity 99% 16s rRNA gene PCR.This able produce...

10.21161/mjm.12914 article EN cc-by-nc Malaysian Journal of Microbiology 2015-06-01

We report the draft genome sequences of two antimicrobial-producing isolates, Burkholderia sp. strains MSh1 and MSh2, which were isolated from tropical peat swamp forest soil. Putative genes related to different antimicrobial production have been annotated in both sequences.

10.1128/genomea.01032-14 article EN Genome Announcements 2014-10-10

Background: Even though Southeast Asia is generally regarded as the hotspot for antibiotic resistance, there have been limited studies investigating prevalence of resistance among healthy people in region. We aimed to investigate two ß-lactamase genes, ESBL and plasmid-borne AmpC (pAmpC) Enterobacteriaceae a community Malaysia. Methods materials: collected stool samples screened pAmpC-producing using phenotypic genotypic methods. The susceptibility profile isolates towards 13 different...

10.1016/j.ijid.2020.09.078 article EN cc-by-nc-nd International Journal of Infectious Diseases 2020-12-01

The bacterium Dyella sp. strain C9 was isolated from North Selangor Peat Swamp Forest, Malaysia, and studied using whole-genome sequencing.

10.1128/mra.01083-18 article EN Microbiology Resource Announcements 2018-09-26

ABSTRACT We report here the draft genome of Klebsiella sp. strain C31, a bacterial isolate from North Selangor peat swamp forest in Malaysia. The putative genes for biogeochemical processes were annotated and investigated.

10.1128/genomea.00560-18 article EN Genome Announcements 2018-06-20

ABSTRACT We report the draft genome sequence of Paenibacillus sp. strain MSt1, which has broad-range antimicrobial activity, isolated from tropical peat swamp soil. Genes involved in biosynthesis are found to be present this genome.

10.1128/genomea.01024-14 article EN Genome Announcements 2014-10-10

ABSTRACT We report here the draft genome sequences of a bacterial isolate, Dyella sp. strain C11, which was isolated from Malaysian tropical peat swamp forest. The putative genes for biogeochemical processes were annotated, and deposited in an online database.

10.1128/genomea.00459-18 article EN Genome Announcements 2018-06-20
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