A5100661962- Periodontal Regeneration and Treatments
- Dental Implant Techniques and Outcomes
- Bone Tissue Engineering Materials
- Glaucoma and retinal disorders
- Oral and gingival health research
- Dental Radiography and Imaging
- Corneal surgery and disorders
- Wound Healing and Treatments
- Oral and Maxillofacial Pathology
- dental development and anomalies
- Ophthalmology and Visual Impairment Studies
- Polymer Surface Interaction Studies
- Nanoplatforms for cancer theranostics
- Graphene and Nanomaterials Applications
- Retinal Diseases and Treatments
- Colorectal and Anal Carcinomas
- Orthopedic Infections and Treatments
- Bacterial biofilms and quorum sensing
- Orthodontics and Dentofacial Orthopedics
- Tendon Structure and Treatment
- Hemostasis and retained surgical items
- Anesthesia and Neurotoxicity Research
- Intraocular Surgery and Lenses
- Lipid Membrane Structure and Behavior
- RNA Interference and Gene Delivery
Wuhan University
2015-2025
Shanghai Eye Disease Prevention & Treatment Center
2020-2025
University of Bern
2024
Mongolian University of Science and Technology
2024
Tongji University
2024
Binzhou University
2024
Binzhou Medical University
2024
Stomatology Hospital
2023
Ministry of Education
2022
University of Pennsylvania
2020
Extracellular vesicles (EVs) are involved in the regulation of cell physiological activity and reconstruction extracellular environment. Matrix (MVs) a type EVs released by bone-related functional cells, they participate mineralization. Here, we report bioinspired MVs embedded with black phosphorus (BP) functionalized cell-specific aptamer (denoted as Apt-bioinspired MVs) for stimulating biomineralization. The can direct to targeted increasing concentration inorganic phosphate originating...
To solve the challenge of poor knee repair, an aptamer-bilayer scaffold is designed for autologous mesenchymal stem cell (MSC) recruitment and osteochondral regeneration. The can efficiently recruit MSCs to defect induce directional differentiation MSCs, thus successfully achieving simultaneous regeneration cartilage bone in joint. As a service our authors readers, this journal provides supporting information supplied by authors. Such materials are peer reviewed may be re-organized online...
Abstract Platelet-rich fibrin (PRF) has been widely used owing to its ability stimulate tissue regeneration. To date, few studies have described the antibacterial properties of PRF. Previously, PRF prepared by horizontal centrifugation (H-PRF) was shown contain more immune cells than leukocyte- and platelet-rich (L-PRF). This study aimed compare antimicrobial effects PRFs against Staphylococcus aureus Escherichia coli in vitro determine whether correlated with number cells. Blood samples...
Abstract Objectives To compare the accuracy of immediate implant placement cylindrical implants (CI) and tapered (TI) different lengths using a robotic dental system. Materials Methods CI TI three (8, 10, 12 mm) each were digitally planned placed in three‐dimensional printed extraction socket model under guidance. There six groups with samples group, resulting total 18 samples. Implant angular deviation, platform point deviation (total, lateral, depth), apical depth) recorded compared...
Osteomyelitis is primarily caused by bacterial infections, and treatment requires precise sequential therapy, including antibacterial therapy in the early stages bone defect reconstruction later stages. We aimed to synthesize core–shell-structured zinc oxide/silver sulfide heterogeneous nanoparticles (ZnO/Ag2S NPs) using wet chemical methods. Using density functional theory ultraviolet photoelectron spectroscopy, we showed that optimized band structure endowed ZnO/Ag2S NPs with photodynamic...
ABSTRACT Objectives To compare the clinical effectiveness of a novel bioceramic (BC) with control xenograft (BO) for guided bone regeneration (GBR) performed simultaneously implant placement. Materials and Methods This study enrolled patients insufficient volume who required GBR during placement to increase width using either BC or BO. Outcome measures included dimensional reduction in buccal thickness measured by cone beam computed tomography immediately post‐surgery at 6 months...
To assess the implant accuracy, safety, and efficiency between robotic-assisted freehand dental placement with a half-year follow-up. Patients requiring single-tooth restorations were recruited randomized into two groups: surgery surgery. The accuracy of positioning was compared by assessing immediate postoperative CBCT scans against preoperative planning software. Intraoperative complications recorded, data analyzed using an intention-to-treat approach. time required for in each group...
To compare keratometric astigmatism (ΔK) and total corneal (ΔTK) calculated by the IOLMaster 700 in cataract cases with regular ≥ 0.75 diopters (D). This study was a secondary analysis of database patients who had undergone examination between May 2021 March 2022 at Shanghai Eye Disease Prevention Treatment Center. The Surgically Induced Astigmatism Calculator v2.1 used to examine vector errors ΔK ΔTK. Subgroup analyses were performed based on axis, magnitude, age, gender, mean simulated...
Periodontitis, a leading cause of adult tooth loss and linked to various systemic diseases, is promoted by subgingival plaque biofilms, with Streptococci as early colonizers responsible for surface adhesion. Current studies adhesion have focused on bacteria adhesins acquired protein membranes the surface, yet no critical proteins implications overall been reported. Here, we identified that "Barrel-like domain" streptococcal EF-Tu facilitates cell-surface attachment, promotes biofilm...
Abstract Bone grafts are widely used in bone regeneration to increase the speed and quality of new formation. While they routinely characterized based on their biocompatible bioactive properties, also exert a profound impact host immune responses, which turn can display significant effect healing repair process. In this study, we investigated role macrophage behavior deproteinized bovine matrix (DBBM, BioOss) investigate creating either pro‐ or anti‐inflammatory microenvironment for tissue...
Horizontal platelet-rich fibrin (H-PRF) contains a variety of bioactive growth factors and cytokines that play key role in the process tissue healing regeneration. The blood collection tubes used to produce Solid-PRF (plasmatrix (PM) tubes) have previously been shown great impact on morphology, strength composition final H-PRF clot. Therefore, modification PM is an important step toward future optimization PRF. To this end, we innovatively modified inner wall surface with plasma adjusted gas...
Development of a cell-free scaffold with excellent mechanical properties and osteoconductivity is significant need for bone regeneration. Herein, reduced graphene oxide (rGO) functionalized hierarchical macro-mesoporous bioactive glass integrated an osteoblast-specific aptamer rationally designed to recruit induce the rapid differentiation osteoblasts This exhibits macroporous structure fully interconnected open pores shows Young's modulus ∼80 kPa, which provides strong support growth tissue...
Alveolar bone defects caused by tooth loss often lead to challenges in implant dentistry, with a need for development of optimal biomaterials predictably rebuild these tissues. To address this problem, we fabricated novel block using platelet-rich fibrin (PRF) and Deproteinized Bovine Bone Mineral (DBBM), characterized their mechanical biological properties. The was prepared mixing DBBM, Liquid-PRF, Solid-PRF fragments various combinations as follows: (1) BLOCK-1 made + (2) BLOCK-2...
Abstract With the rapid development of nanotechnology, nanoparticles (NPs) are widely used in all fields life. Nowadays, NPs have shown extraordinary antimicrobial activities and become one most popular strategies to combat antibiotic resistance. Whether they equally effective combating bacterial persistence, another important reason leading treatment failure, remains unknown. Persister cells a small subgroup phenotypic drug‐tolerant an isogenic population. Here, various types combination...
Objective This study aims to develop a compound biomaterial achieve effective soft tissue regeneration. Methodology Compound hyaluronic acid (CHA) and liquid horizontal-platelet-rich fibrin (H-PRF) were mixed at ratio of 1:1 form CHA-PRF gel. Human gingival fibroblasts (HGFs) used in this study. The effect CHA, H-PRF, the gel on cell viability was evaluated by CCK-8 assays. Then, collagen formation deposition qRT‒PCR immunofluorescence analysis. Finally, qRT‒PCR, analysis, Transwell assays,...
To reveal the force profiles recorded by haptic autonomous robotic feedback during transcrestal sinus floor elevation (TSFE) process, providing a reference for surgery strategy TSFE.
Treatment of bacterial infections due to the fast emergence drug-resistant bacteria is a significant challenge faced in modern medicine. Here authors report drug-induced self-assembly nanoantibiotic for treating infection, with temperature/pH-sensitivity, synergistic antibacterial effect silver and antibiotics, immunoregulatory effect. In this nanoantibiotic, smart polymer p(N-isopropylacrylamide-b-acrylic acid) triblock (PNA) utilized encapsulate drugs provides convenience preparing...
Abstract Background In the past few decades, very little research has been carried out to modify implant surfaces improve osteointegration through regulation of immune cells. Purpose The aim this study is investigate whether poly(dopamine) (pDA)‐assisted immobilization IL4 on titanium could modulate inflammatory profile macrophages in vitro and search for possibility enhancing integration way. Material Methods surface composition, topography, roughness SLA, SLA‐pDA, SLA‐pDA‐IL4 discs were...