A5027358959- Immunotherapy and Immune Responses
- Mesenchymal stem cell research
- T-cell and B-cell Immunology
- Reproductive System and Pregnancy
- Immune Response and Inflammation
- Toxoplasma gondii Research Studies
- MicroRNA in disease regulation
- Endometriosis Research and Treatment
- Cancer-related molecular mechanisms research
- Parasitic Infections and Diagnostics
- Extracellular vesicles in disease
- Electrospun Nanofibers in Biomedical Applications
- Innovations in Medical Education
- Tissue Engineering and Regenerative Medicine
- Medical Education and Admissions
- Circular RNAs in diseases
- Multiple Sclerosis Research Studies
- Cervical Cancer and HPV Research
- Psoriasis: Treatment and Pathogenesis
- Rabies epidemiology and control
- Galectins and Cancer Biology
- Parasitic infections in humans and animals
- Cardiac Fibrosis and Remodeling
- Problem and Project Based Learning
- S100 Proteins and Annexins
Ahvaz Jundishapur University of Medical Sciences
2014-2024
Islamic Azad University, Ahvaz Branch
2023
Tarbiat Modares University
2015
Tehran University of Medical Sciences
2011
In the embryonic heart, electrical impulses propagate in a unidirectional manner from sinus venosus and appear to be involved cardiogenesis. this work, aligned random polyaniline/polyetersulfone (PANI/PES) nanofibrous scaffolds doped by Camphor-10-sulfonic acid (β) (CPSA) were fabricated via electrospinning used conduct multidirectional fashion, respectively. A bioreactor was subsequently engineered apply cells cultured on PANI/PES scaffolds. We established cardiovascular disease-specific...
Regulatory T (Treg) cells are essential for maintenance of peripheral tolerance and prevention autoimmune diseases in part by producing immunosuppressive cytokines. Recently, microRNAs (miRNAs) have also been involved disorders, not least their crucial role the regulation Treg biology function. We simultaneously investigated concentration IL-35, IL-10, TGF-β, sCD25 supernatant cell culture expression patterns several miRNAs CD4+CD25+ CD127−/low FoxP3+ Tregs ulcerative colitis (UC) patients....
The development of a maternal immune response to fetal antigens and deficiency in regulatory T-cells (Tregs) may lead preeclampsia. A plausible explanation for the reduced Treg cell function women with preeclampsia is presence exhausted cells which express CD279 or programmed death receptor-1 (PD-1), negative molecule associated limited proliferative capacity suppression.To assess number CD4+ CD25 high CD279+ (PE group) healthy pregnant (HP during third trimester pregnancy.Three-color flow...
Introduction: Breast cancer is considered the most frequent type of in women with high mortality worldwide, and importantly, it second common cancer. However, some breast cancer-related risk factors remain unknown. So, current study was designed to evaluate effect Toxocara canis on biomarkers correlated proliferation, apoptosis, inflammation, angiogenesis 4T1 tumor-bearing mice infected for first time. Methods: Mice were categorized into four groups: A) control, B) treated 4T1+ canis, C) D)...
Background: MicroRNA-155 is a key player in inflammatory reactions, carcinogenesis, and tumor development. In this study, polymorphism of miRNA-155 rs767649 T>A its gene suppressor cytokine signaling-1 (SOCS-1) expression were investigated relation to cancer susceptibility development breast (BC) patients. Materials Methods: Polymorphism was evaluated between population 174 patients with BC 129 controls using restriction fragment length the miR-155 SOCS-1 examined peripheral blood...
Women afflicted with recurrent spontaneous abortion (RSA) and repeated implantation failure (RIF) may have immune abnormalities. The role of vitamin D has been demonstrated in the function system.To assess percentage CD3+ T cells their relationship level serum or 1,25-dihydroxy D3 (the active form vitamin) women RSA RIF.In this case-control study, peripheral blood was obtained from patient healthy control groups. ratio CD3+T cell activated CD69+T investigated using flow cytometry. levels...
Mesenchymal stem cells are gaining attention in medicine because of their anti-inflammatory and immunosuppressive properties. Inflammatory conditions can modulate immune responses mesenchymal cells.We investigated the expression long noncoding RNAs (RMRP, MALT1, NKILA,THRIL, Linc-MAF-4) humanWharton jelly primed with polyinosinicpolycytidylic acid.
Mesenchymal stem cells (MSCs) are a potential cell therapy candidate for autoimmune and inflammatory diseases due to their multilineage capacity immune modulating function. MSCs exert immunomodulatory effects on target through the secretion of exosomes. Inflammatory conditions such as Toll-like receptors (TLRs) engagement can change biological functions activities contents exosomes derived from changed. Regulatory T-cells (Treg) crucial maintaining homeostasis self-tolerance. Our study aimed...
Background: Natural killer (NK) cells play a critical role in the pathogenesis of endometriosis. Moreover, normal vitamin D level is remarkably associated with an optimal immune response. So, there may be probable relationship between these factors and endometriotic women. Objective: This study aimed to evaluate percentage NK their subsets serum levels interferon-gamma (IFN-γ) women Materials Methods: In this case-control study, 29 stage III-IV endometriosis 30 healthy controls were...