A5070980476- Gastrointestinal disorders and treatments
- Salmonella and Campylobacter epidemiology
- Listeria monocytogenes in Food Safety
- Bacterial Genetics and Biotechnology
- DNA Repair Mechanisms
- Essential Oils and Antimicrobial Activity
- Genomics and Phylogenetic Studies
- Tracheal and airway disorders
- Congenital Heart Disease Studies
- Advances in Oncology and Radiotherapy
- Microbial Metabolic Engineering and Bioproduction
- Plant Disease Resistance and Genetics
- Colorectal and Anal Carcinomas
- RNA and protein synthesis mechanisms
- Health and Medical Research Impacts
- Protein Structure and Dynamics
- Enzyme Structure and Function
- Congenital Diaphragmatic Hernia Studies
- Helicobacter pylori-related gastroenterology studies
- Plant Pathogens and Resistance
- Chromosomal and Genetic Variations
Michigan State University
2020-2022
Sisters of Charity Hospital
1902
Worldwide, the cultivated potato, Solanum tuberosum L., is No. 1 vegetable crop and a critical food security crop. The genome sequence of DM1-3 516 R44, doubled monoploid clone S. Group Phureja, was published in 2011 using whole-genome shotgun sequencing approach with short-read data. Current advanced technologies now permit generation near-complete, high-quality chromosome-scale assemblies at minimal cost.Here, we present an updated version R44 (v6.1) Oxford Nanopore Technologies long reads...
Studying proteins through the lens of evolution can reveal conserved features, lineage-specific variants, and their potential functions. MolEvolvR (https://jravilab.org/molevolvr) is a novel web-app enabling researchers to visualize molecular interest in phylogenetic context across tree life, spanning all superkingdoms. The accepts multiple input formats — protein/domain sequences, homologous proteins, or domain scans and, using general-purpose computational workflow, returns detailed...
A fundamental requirement for life is the replication of an organism's DNA. Studies in Escherichia coli and Bacillus subtilis have set paradigm DNA bacteria. During initiation E. B. subtilis, replicative helicase loaded onto at origin by ATPase loader. However, most bacteria do not encode homologs to loaders subtilis. Recent work has identified DciA protein as a predicted operator that may perform function analogous proteins, which are defined presence DUF721 domain (termed herein),...
Listeria monocytogenes (Lm) is a bacterial pathogen that causes listeriosis in immunocompromised individuals, particularly pregnant women. Several virulence factors support the intracellular lifecycle of Lm and facilitate cell-to-cell spread, allowing it to occupy multiple niches within host cross-protective barriers, including placenta. One family factors, internalins, contributes pathogenicity by inducing specific uptake conferring tissue tropism. Over 25 internalins have been identified...
Abstract Listeria monocytogenes ( Lm ) is a bacterial pathogen that causes listeriosis in immunocompromised individuals, particularly pregnant women. Several virulence factors support the intracellular lifecycle of and facilitate cell-to-cell spread, allowing it to occupy multiple niches within host cross protective barriers, including placenta. One family factors, internalins, contributes pathogenicity by inducing specific uptake conferring tissue tropism. Over 25 internalins have been...
ABSTRACT A fundamental requirement for life is the replication of an organism’s DNA. Studies in Escherichia coli and Bacillus subtilis have set paradigm DNA bacteria. During initiation E. B. , replicative helicase loaded onto at origin by ATPase loader. However, most bacteria do not encode homologs to loaders . Recent work has identified DciA protein as a predicted operator that may perform function analogous proteins, which are defined presence DUF721 domain (termed herein), conserved but...