A5038590448- Schizophrenia research and treatment
- Mental Health and Psychiatry
- Bipolar Disorder and Treatment
- Tryptophan and brain disorders
- Child and Adolescent Psychosocial and Emotional Development
- Stress Responses and Cortisol
- Obsessive-Compulsive Spectrum Disorders
- Autism Spectrum Disorder Research
- Genetic Associations and Epidemiology
- Functional Brain Connectivity Studies
- Mental Health Research Topics
- Personality Disorders and Psychopathology
- Diet and metabolism studies
- Action Observation and Synchronization
- Assisted Reproductive Technology and Twin Pregnancy
- Neurotransmitter Receptor Influence on Behavior
- Hearing Impairment and Communication
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Psychosomatic Disorders and Their Treatments
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Optimism, Hope, and Well-being
- Birth, Development, and Health
- Phosphodiesterase function and regulation
- Child and Animal Learning Development
- Treatment of Major Depression
Mercer University
2018-2019
Emory University
2006-2016
Augusta University
2009-2010
Charlie Norwood VA Medical Center
2010
Schizotypal personality disorder is characterized by interpersonal and verbal communication deficits. Despite the important role of gesture in social communication, no published reports examine use individuals with SPD. In this study, raters code from videotaped interviews unmedicated adolescents SPD, other disorders, or Axis II disorder. Results indicate that SPD show significantly fewer gestures but do not differ groups overall rate movement. The findings are discussed light brain regions...
Abstract Objective: Substantial converging evidence from schizophrenia researchers indicates that the duration of untreated psychosis (DUP) represents a modifiable predictor outcome during early course schizophrenia. As DUP is increasingly assessed in research settings, focused attention should be given to complexities measurement this critical construct. In review, three aspects are addressed: (i) definition DUP, (ii) operational criteria for construct, and (iii) methods used measurement....
Recent research implicates the catechol-O-methyltransferase (COMT) ValMet polymorphism in stress sensitivity, through modulation of hypothalamic-pituitary-adrenal (HPA) function. In healthy samples, Met homozygosity has been associated with greater HPA activity (i.e., cortisol) and though findings are mixed among clinical samples. To date, there no reports examining baseline or longitudinal changes as a function COMT genotype youth. This study tested hypothesis that would be cortisol...
Cognitive deficits have been documented in schizophrenia and spectrum disorders. This study examines cognitive functioning its relation to symptoms adolescents with schizotypal personality disorder (SPD). Participants are 89 recruited for a of youth at risk Axis I disorders, especially psychosis. At intake, 34 met criteria SPD, 38 another II and/or conduct (Other disorder—OD), 17 did not currently meet any DSM-IV (normal control—NC). initial assessment, was measured using subtests from the...
<p>Treatment Delay in the Early Course of Schizophrenia and Duration Untreated Psychosis </p><p>Michael T. Compton, MD, MPH; Sandra M. Goulding, Beth Broussard, MPH, CHES; Hanan Trotman, MA</p> <p>In recent decades, treatment delay early course schizophrenia has evolved as an issue great interest to researchers, especially psychosis researchers. This is partly derived from accumulating research evidence that delaying new-onset psychosis, like any emerging...
Developmental changes in the brain are now a central feature of most etiological theories schizophrenia. From fetal period, which vulnerability is presumed to originate, emergence clinical illness adolescence, setting stage for first episode psychosis. A host factors that have ability alter development been linked with Heritable genetic may increase risk aberrant development, and molecular studies revealing mutations epigenetic events can also derail normal developmental processes. Prenatal...
Abstract Atypical antipsychotics (AT) and stress are related to weight gain in individuals with severe mental illness. This cross‐sectional study examines AT use, stressful life events, baseline a sample of youth at clinical high risk for psychosis. Results showed that dependent desirable events moderated the relationship between use after controlling demographic factors selective serotonin reuptake inhibitor antidepressant (AD) use. The relation AD was explored as secondary analysis no...
Rationale: Given the dearth of research on prevalence and clinical correlates first rank symptoms in first-episode psychosis samples, this study focused a relatively homogenous sample hospitalized, first-episode, urban, African-American patients.Objective: To determine frequencies eleven based previously published definitions, to conduct correlations an exploratory factor analysis reveal any potential latent structure symptoms, assess associations between several select variables.Methods:...