Jason McCarthy

ORCID: 0000-0003-0546-0076
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About
Contact & Profiles
Research Areas
  • Stroke Rehabilitation and Recovery
  • Cardiovascular and exercise physiology
  • High Altitude and Hypoxia
  • Acute Ischemic Stroke Management
  • Multiple Sclerosis Research Studies
  • Heart Rate Variability and Autonomic Control
  • Autoimmune and Inflammatory Disorders Research
  • Balance, Gait, and Falls Prevention
  • Chronic Obstructive Pulmonary Disease (COPD) Research
  • Muscle activation and electromyography studies
  • Sports Performance and Training
  • Long-Term Effects of COVID-19
  • Prosthetics and Rehabilitation Robotics
  • Sports injuries and prevention
  • Transcranial Magnetic Stimulation Studies
  • Effects of Vibration on Health
  • Motor Control and Adaptation
  • Non-Invasive Vital Sign Monitoring
  • Neurogenesis and neuroplasticity mechanisms
  • Nerve injury and regeneration
  • Cerebral Palsy and Movement Disorders
  • Apelin-related biomedical research
  • Botulinum Toxin and Related Neurological Disorders
  • Clinical practice guidelines implementation
  • Cardiovascular and Diving-Related Complications

Memorial University of Newfoundland
2017-2024

Homerton University Hospital
2021

St. John’s Health Sciences Centre
2008

Midwestern State University
2007

Baylor University
2002-2003

University of New Mexico
2003

Background and Purpose Previous research suggests that patients receiving inpatient stroke rehabilitation are sedentary although there is little data to confirm this supposition within the Canadian healthcare system. The purpose of cross-sectional study was observe two weeks in a tertiary center determine patients' activity levels time.Methods Heart rate (HR) accelerometer were measured using an Actiheart monitor for seven consecutive days, 24 h/day, on second week last admission....

10.1080/10749357.2018.1458461 article EN Topics in Stroke Rehabilitation 2018-04-03

Background. Paired exercise and cognitive training have the potential to enhance cognition by “priming” brain upregulating neurotrophins. Methods. Two-site randomized controlled trial. Fifty-two patients >6 months poststroke with concerns about impairment trained 50 70 minutes, 3× week for 10 weeks 12-week follow-up. Participants were 1 of 2 physical interventions: Aerobic (>60% VO 2peak using <10% body weight–supported treadmill) or Activity (range movement functional tasks)....

10.1177/1545968319832605 article EN Neurorehabilitation and neural repair 2019-02-28

Objectives: Our objectives were: 1) to determine whether maximal aerobic exercise increased serum neurotrophins in chronic stroke and 2) the factors that predict resting exercise-dependent levels.Methods: We investigated potential predictors of insulin-like growth factor-1 brain-derived neurotrophic factor among 35 patients. Predictors from three domains (demographic, disease burden, cardiometabolic) were entered into 4 separate stepwise linear regression models with outcome variables:...

10.1080/01616412.2018.1564451 article EN Neurological Research 2019-01-08

Abstract Background Aerobic training has the potential to restore function, stimulate brain repair, and reduce inflammation in people with Multiple Sclerosis (MS). However, disability, fatigue, heat sensitivity are major barriers exercise for MS. We aimed determine feasibility of conducting vigorous harness-supported treadmill a room cooled 16 °C (10 weeks; 3times/week) examine longer-term effects on markers among those using ambulatory aids. Methods Ten participants (9 females) aged 29 74...

10.1186/s12883-020-1611-0 article EN cc-by BMC Neurology 2020-01-22

Stroke is a leading cause of disability and death worldwide. Care stroke patients both complex resource-intensive. Understanding this complexity crucial for improving healthcare delivery. This study aimed to model analyze the care system. Data were gathered through document review interviews with 17 professionals in city eastern Canada. The Functional Resonance Analysis Method (FRAM) was employed system, identify sources variability, propose solutions improve identified 73 interconnected...

10.1016/j.hfh.2024.100084 article EN cc-by-nc-nd Human Factors in Healthcare 2024-07-14

To determine whether stroke survivors could maintain workloads during functional task practice that can reach moderate levels of cardiometabolic stress (i.e., ≥40% oxygen uptake reserve ([Formula: see text]O

10.3389/fphys.2017.00809 article EN cc-by Frontiers in Physiology 2017-10-26

Purpose: To determine the effectiveness of a community re-integration exercise initiative on function, mood, participation, and adherence for persons with moderate to severe neurological conditions (stroke, multiple sclerosis, etc.). Methods

10.3233/nre-141090 article EN Neurorehabilitation 2014-09-03

Objective: Evaluate intensity-dependent effects of a single bout high intensity interval training (HIIT) compared to moderate constant-load exercise (MICE) on corticospinal excitability (CSE) and upper limb performance in chronic stroke. Design: Randomized cross-over trial. Setting: Research laboratory tertiary rehabilitation hospital. Participants: Convenience sample 12 stroke survivors. Outcome measures: Bilateral CSE measures intracortical inhibition facilitation, motor thresholds, evoked...

10.3389/fphys.2018.00827 article EN cc-by Frontiers in Physiology 2018-07-02

Abstract A coherent perception of spatial orientation is key in maintaining postural control. To achieve this the brain must access sensory inputs encoding both body and head position integrate them with incoming visual information. Here we isolated contribution proprioception to verticality further investigated whether changing without moving can modulate dependence—the extent which an individual relies on cues for orientation. Spatial was measured ten healthy individuals [6 female; 25–47...

10.1007/s00221-021-06146-0 article EN cc-by Experimental Brain Research 2021-06-13

To identify variables associated with rehabilitation length of stay (LOS) and prosthetic fitting success for people lower limb amputation (LLA).Retrospective analysis clinically collected cohort.Canadian inpatient hospital.Consecutive individuals LLA (N=103) admitted (mean age, 65.3±10.6y).Not applicable.Independent included the Lower Limb Amputee Measurement Scale (LLAMS), which is a 31-question tool to predict LOS items in medical, cognitive, social, physical, activities daily living,...

10.1016/j.arrct.2020.100084 article EN cc-by-nc-nd Archives of Rehabilitation Research and Clinical Translation 2020-09-19

The purpose of this study was to establish an objective method for identifying the heart-rate threshold (HRT) in cyclists. Fifty-six male cyclists were tested on a cycle ergometer volitional fatigue. Identification HRT used increase above logarithmic regression line best fit, coupled with crossover linear fit. measures Vco(2) and blood lactate ventilatory (VT) (HLaT), respectively, as criterion validate HRT. Comparison VT HLaT showed significant associations (r = 0.98). Statistical variance...

10.1519/r-16084.1 article EN The Journal of Strength and Conditioning Research 2005-01-01

The purpose of this case study was to profile maximal exercise and the incidence exercise-induced arterial hypoxemia (EIAH) at three different altitudes within a group competitive cyclists residing training 1,500 m. Ten male (category I or II professional road cyclists: ages, 27.7 ± 6.1; weight, 69.9 6.9 kg) participated in randomly assigned VO2max tests sea level (SL), m 3000 Arterial saturation (pulse oximetry), ventilation, power output (PO) were recorded continuously throughout test....

10.1080/15438620601184364 article EN Research in Sports Medicine 2007-03-01

Moderate-intensity aerobic exercise training is an important treatment strategy to enhance functional recovery and decrease cardiometabolic risk factors after stroke. However, stroke related impairments limit access ergometer-type exercise. The aims of the current study were (1) evaluate whether our task-oriented circuit protocol (intermittent training; IFT) could be used sustain moderate-intensity workloads over a 10-week intervention period, (2) investigate its preliminary effects on...

10.3390/jcm10112423 article EN Journal of Clinical Medicine 2021-05-30

To evaluate the safety and feasibility of performing treadmill aerobic exercise in moderate normobaric hypoxia among chronic hemiparetic stroke survivors.Observational study using convenience sampling.Research laboratory a tertiary rehabilitation hospital.Chronic survivors who could walk at least 10-m with or without assistance had no absolute contraindications to testing.Participants (three male four female) were asked complete three exposure protocols within single session. First, they...

10.3389/fphys.2021.702439 article EN cc-by Frontiers in Physiology 2021-08-16

Abstract Background: Aerobic training has the potential to restore function, stimulate brain repair, and reduce inflammation in people with Multiple Sclerosis (MS). However, disability, fatigue, heat sensitivity are major barriers exercise for MS. We aimed determine feasibility of conducting vigorous harness-supported treadmill a room cooled 16°C (10 weeks; 3times/week) examine longer-term effects on markers among those using ambulatory aids. Methods: Ten participants (9 females) aged 29 74...

10.21203/rs.2.17182/v3 preprint EN cc-by Research Square (Research Square) 2020-01-13

Blood lactate appearance and clearance has been closely linked to fatigue (Grassi et al., 1996). At altitude during intense levels of exercise, there is an increase in formation, a drop pH increased rate. PURPOSE: It the purpose this study compare percent recovery, based on post-exercise (PE) blood (La), with sea level natives. METHODS: Fourteen (N = 14) subjects living training at (n 7) were matched by demographic measures. Each subject completed cycle ergometer protocol increasing workload...

10.1097/00005768-200205001-01336 article EN Medicine & Science in Sports & Exercise 2002-05-01

Abstract Background: Aerobic training has the potential to restore function, stimulate brain repair, and reduce inflammation in people with Multiple Sclerosis (MS). However, disability, fatigue, heat sensitivity are major barriers exercise for MS. We aimed determine feasibility of conducting vigorous harness-supported treadmill a room cooled 16°C (10 weeks; 3times/week) examine longer-term effects on markers among those using ambulatory aids. Methods: Ten participants (9 females) aged 29 74...

10.21203/rs.2.17182/v2 preprint EN cc-by Research Square (Research Square) 2019-12-23

Abstract Background: Aerobic training has the potential to restore function, stimulate brain repair, and reduce inflammation in people with Multiple Sclerosis (MS). However, disability, fatigue, heat sensitivity are major barriers exercise for MS. We aimed determine feasibility of conducting vigorous harness-supported treadmill a room cooled 16°C (10 weeks; 3times/week) examine longer-term effects on markers among those using ambulatory aids. Methods: Ten participants (9 females) aged 29 74...

10.21203/rs.2.17182/v1 preprint EN Research Square (Research Square) 2019-11-14

Thresholds associated with exercise physiology (i.e., heart rate, lactate, ventilatory) are defined as variables showing a disproportionate rate change work increases proportionately. Unlike many identified thresholds, the threshold (HRT) has repeatedly shown increased and decreased changes continues to be controversial. PURPOSE The purpose of this study was establish an objective method for identifying HRT, show associations criterion measures. METHODS Subjects were twenty-five (N = 25)...

10.1097/00005768-200305001-00637 article EN Medicine & Science in Sports & Exercise 2003-05-01
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