A5065922788- Plant-Microbe Interactions and Immunity
- Plant Pathogenic Bacteria Studies
- Plant Stress Responses and Tolerance
- Plant Parasitism and Resistance
- Plant nutrient uptake and metabolism
- RNA Research and Splicing
- RNA and protein synthesis mechanisms
- Bacterial biofilms and quorum sensing
- Immune Cell Function and Interaction
- Fungal and yeast genetics research
- Toxoplasma gondii Research Studies
- Pneumocystis jirovecii pneumonia detection and treatment
- interferon and immune responses
- Photosynthetic Processes and Mechanisms
- Plant Molecular Biology Research
- CRISPR and Genetic Engineering
- Adenosine and Purinergic Signaling
Center for Research in Agricultural Genomics
2019-2025
Universitat de Barcelona
2022
Consejo Superior de Investigaciones Científicas
2022
Imperial College London
2017
Stress granules (SGs) are highly conserved cytoplasmic condensates that assemble in response to stress and contribute maintaining protein homeostasis. These membraneless organelles dynamic, disassembling once the is no longer present. Persistence of SGs due mutations or chronic has been often related age-dependent protein-misfolding diseases animals. Here, we find metacaspase MC1 dynamically recruited into upon proteotoxic Arabidopsis (Arabidopsis thaliana). Two predicted disordered regions,...
ABSTRACT Plants utilize cell surface-localized pattern recognition receptors (PRRs) and intracellular nucleotide-binding leucine-rich repeat (NLR) to detect non-self elicit robust immune responses. Fine-tuning the homeostasis of these is critical prevent their hyperactivation. Here, we show that Arabidopsis plants lacking metacaspase 1 ( At MC1) display autoimmunity dependent on signalling components downstream NLR PRR activation. Overexpression a catalytically inactive MC1 in an atmc1...
Increasing drought phenomena pose a serious threat to agricultural productivity. Although plants have multiple ways respond the complexity of stress, underlying mechanisms stress sensing and signaling remain unclear. The role vasculature, in particular phloem, facilitating inter-organ communication is critical poorly understood. Combining genetic, proteomic physiological approaches, we investigated AtMC3, phloem-specific member metacaspase family, osmotic responses Arabidopsis thaliana....
Eukaryotes are endowed with sophisticated innate immune systems to recognize non-self and halt pathogen proliferation. Activation of cell death at the site attempted ingress is a common strategy used by plants animals restrict proliferation trigger responses in surrounding tissues. As such, immunogenic shares several features both that will be discussed this article, namely: (i) it triggered activation NLR receptors—often through oligomerization; (ii) results disruption plasma membrane...
Abstract Increasing drought phenomena pose a serious threat to agricultural productivity. Although plants have multiple ways respond the complexity of stress, underlying mechanisms stress sensing and signalling remain unclear. The role vasculature, in particular phloem, facilitating inter-organ communication is critical. Here, we investigated AtMC3, phloem-specific member metacaspase family, osmotic responses Arabidopsis thaliana . Overexpression AtMC3 conferred tolerance by enhancing...
Abstract Recognition of a pathogen by the plant immune system often triggers form regulated cell death traditionally known as hypersensitive response. This type occurs precisely at site recognition, and it is restricted to few cells. Extensive research has shed light into how receptors are mechanistically activated. However, central key question remains largely unresolved: does zonation take place what mechanisms that underpin this phenomenon? As consequence, bona fide transcriptional...