A5028844556- Plant Molecular Biology Research
- Plant nutrient uptake and metabolism
- Photosynthetic Processes and Mechanisms
- Plant Reproductive Biology
- Plant biochemistry and biosynthesis
- Antioxidant Activity and Oxidative Stress
- Plant Stress Responses and Tolerance
- Light effects on plants
- Lipid metabolism and biosynthesis
- Amino Acid Enzymes and Metabolism
- Leaf Properties and Growth Measurement
- RNA Research and Splicing
- Cellular transport and secretion
- Trauma and Emergency Care Studies
- Enzyme Production and Characterization
- Plant responses to water stress
- Single-cell and spatial transcriptomics
- Hip and Femur Fractures
- Genomics and Phylogenetic Studies
- Genomics and Chromatin Dynamics
- RNA modifications and cancer
- Polyamine Metabolism and Applications
- Phytase and its Applications
- Polysaccharides and Plant Cell Walls
- Legume Nitrogen Fixing Symbiosis
ETH Zurich
2016-2024
University of Miami Health System
2023
AO Foundation
2023
École Polytechnique Fédérale de Lausanne
2015-2022
University of Lausanne
2011-2017
Center for Research in Agricultural Genomics
2009-2014
Institut Universitari d'Investigació en Atenció Primària Jordi Gol
2009
Universitat de Barcelona
2008
Consejo Superior de Investigaciones Científicas
2008
Summary Carotenoids are plastidial isoprenoids essential for plant life. In Arabidopsis thaliana carotenoid biosynthesis is strongly upregulated when seedlings that germinate in the dark (etiolated) emerge from soil and light derepresses photomorphogenesis, causing etioplasts to become chloroplasts. We found also induced deetiolation derepressed absence of actual light, eventually resulting improved greening (chlorophyll accumulation) upon illumination. The increased production carotenoids...
Peptide signaling presumably occupies a central role in plant development, yet only few concrete examples of receptor-ligand pairs that act the context specific differentiation processes have been described. Here we report second-site null mutations Arabidopsis leucine-rich repeat receptor-like kinase gene barely any meristem 3 ( BAM3 ) perfectly suppress postembryonic root growth defect and associated perturbed protophloem development brevis radix brx mutant. The roots bam3 mutants...
Significance The emergence of vascular tissues played a central role in the plant conquest land. Both xylem and phloem are essential for development flowering plants, yet little is known about molecular genetic control specification differentiation. Here we show that delicate quantitative interplay between two opposing signaling pathways determines cellular commitment to protophloem sieve element fate root meristems model Arabidopsis thaliana . Our data suggest recently described...
Protophloem is a specialized vascular tissue in growing plant organs, such as root meristems. In Arabidopsis mutants with impaired primary protophloem differentiation, brevis radix (brx) and octopus (ops), meristematic activity consequently overall growth are strongly reduced. Second site mutation the protophloem-specific presumed phosphoinositide 5-phosphatase COTYLEDON VASCULAR PATTERN 2 (CVP2), but not its homolog CVP2-LIKE 1 (CVL1), partially rescues brx defects. Consistent this finding,...
Abscisic acid (ABA) is a hormone that plays vital role in mediating abiotic stress responses plants. Salt exposure induces the synthesis of ABA through cleavage carotenoid precursors (xanthophylls), which are found at very low levels roots. Here we show de novo biosynthesis salt-treated Arabidopsis thaliana roots involves an organ-specific induction biosynthetic pathway. Upregulation genes encoding phytoene synthase (PSY) and other enzymes pathway producing was observed but not shoots after...
Abstract Arabidopsis root development is orchestrated by signaling pathways that consist of different CLAVATA 3/ EMBRYO SURROUNDING REGION ( CLE ) peptide ligands and their cognate CLV BARELY ANY MERISTEM BAM receptors. How where peptides trigger specific morphological or physiological changes in the poorly understood. Here, we report receptor‐like protein 2 2) pseudokinase CORYNE CRN are necessary to fully sense root‐active peptides. We uncover 3 as 45 receptor biochemically map its binding...
Plant cells can change their identity based on positional information, a mechanism that confers developmental plasticity to plants. This ability, common distinct multicellular organisms, is particularly relevant for plant phloem cells. Protophloem sieve elements (PSEs), one type of conductive cells, act as the main organizers pole, which comprises four cell files organized in conserved pattern. Here, we report how Arabidopsis roots generate reservoir meristematic competent swap identities....
Polyamines, such as putrescine, spermidine and spermine (Spm), are low-molecular-weight polycationic molecules present in all living organisms. Despite their implication plant cellular processes, little is known about molecular mode of action. Here, we demonstrate that polyamines trigger a rapid increase the regulatory membrane lipid phosphatidylinositol 4,5-bisphosphate (PIP2 ), this required for polyamine effects on K+ efflux Arabidopsis roots. Using vivo 32 Pi -labelling seedlings, low...
Increasing drought phenomena pose a serious threat to agricultural productivity. Although plants have multiple ways respond the complexity of stress, underlying mechanisms stress sensing and signaling remain unclear. The role vasculature, in particular phloem, facilitating inter-organ communication is critical poorly understood. Combining genetic, proteomic physiological approaches, we investigated AtMC3, phloem-specific member metacaspase family, osmotic responses Arabidopsis thaliana....
Eukaryotic mRNA transcription and turnover is controlled by an enzymatic machinery that includes RNA polymerase II the 3′ to 5′ exosome. The activity of these protein complexes modulated additional factors, such as nuclear II-associated factor 1 (Paf1c) cytoplasmic Superkiller (SKI) complex, respectively. Their components are conserved across uni- well multi-cellular organisms, including yeast, Arabidopsis, humans. Among them, SKI8 displays multiple facets on top its role in SKI complex. For...
The plant vascular network consists of specialized phloem and xylem elements that undergo two distinct morphogenetic developmental programs to become transport-functional units. Whereas vacuolar rupture is a determinant step in protoxylem differentiation, protophloem never form big central vacuole. Here, we show genetic disturbance phosphatidylinositol 4,5-bis-phosphate [PtdIns(4,5)P2] homeostasis rewires cell trafficking towards the vacuole Arabidopsis thaliana roots. Consequently, an...
Patient-reported outcome (PRO) measurements are validated tools developed to quantify self-reported aspects of capability, mindset, and circumstances in a standardized fashion. While PRO have primarily been used the research realm, growing body work now underscores substantial opportunities applying data generated by these advance patient-centered musculoskeletal care. Specifically, insights into patient's health status derived from measures can augment standard biomedical approach...
Efficient root-to-shoot delivery of water and nutrients in plants relies on the correct differentiation xylem cells into hollow elements. While auxin is integral to formation cells, it remains poorly characterized how each subcellular pool this hormone regulates process. Combining genetic cell biological approaches, we investigated bipartite activity nucleoplasmic vs plasma membrane-associated phosphatidylinositol 4-phosphate kinases PIP5K1 its homolog PIP5K2 Arabidopsis thaliana roots...
Abstract After the perception of vegetation proximity by phytochrome photoreceptors, shade-avoider plants initiate a set responses known as shade avoidance syndrome (SAS). Shade B (phyB) photoreceptor unleashes PHYTOCHROME INTERACTING FACTORs and initiates SAS responses. In Arabidopsis (Arabidopsis thaliana) seedlings, involves rapid massive changes in gene expression, increases auxin production, promotes hypocotyl elongation. Other components, such phyA ELONGATED HYPOCOTYL 5, also...
Carotenoids are plastidial isoprenoids essential for the protection of photosynthetic tissues against excess light. They also serve as precursors apocarotenoid hormones such abscisic acid (ABA) and strigolactones. The first enzyme carotenoid pathway, phytoene synthase (PSY), is main rate-limiting step. Unlike that observed in most plants, PSY encoded by a single gene Arabidopsis thaliana. Whereas induced light tissues, root-specific upregulation expression salt stress ABA has been recently...