A5033653610- Agricultural pest management studies
- Photoreceptor and optogenetics research
- Agricultural Practices and Plant Genetics
- Lanthanide and Transition Metal Complexes
- Circadian rhythm and melatonin
- Insect Pest Control Strategies
- Surfactants and Colloidal Systems
- Retinal Development and Disorders
- Endoplasmic Reticulum Stress and Disease
- Analytical Chemistry and Chromatography
- Insect-Plant Interactions and Control
- Autophagy in Disease and Therapy
- Carbon and Quantum Dots Applications
- South Asian Cinema and Culture
- Neuroscience and Neuropharmacology Research
- Agricultural Science and Fertilization
- Genetics, Aging, and Longevity in Model Organisms
- Photochemistry and Electron Transfer Studies
- Sesame and Sesamin Research
- Genetic and Environmental Crop Studies
- Advanced MRI Techniques and Applications
- ATP Synthase and ATPases Research
- Essential Oils and Antimicrobial Activity
- South Asian Studies and Diaspora
- MRI in cancer diagnosis
National Institute of Science Education and Research
2021-2025
Batra Hospital and Medical Research Centre
2024-2025
University of South Florida
2020-2024
Rice University
2023-2024
ITM University
2023
Swami Keshwanand Rajasthan Agricultural University
2022-2023
Indian Institute of Technology Gandhinagar
2021-2023
Homi Bhabha National Institute
2022-2023
Jai Narain Vyas University
2023
Florida International University
2023
Diamagnetic CEST (diaCEST) MRI contrast agents (CAs) have recently gained immense popularity by virtue of the fact that can be switched on or off merely changing a few experimental parameters, even after agent is administered. However, low efficiency and small solute–solvent offset contrast-generating exchangeable protons so far prevented them from becoming practical option for in vivo applications. Low demands high dosage, while invites unwanted interference endogenous metabolites present...
Palladium-catalyzed tandem activation and functionalization of readily accessible cyclopropanols have been demonstrated to access valuable conjugated enynes from 1,3-diynes with high stereo-selectivity.
Abstract Objective: To analyse risk factors for depression in children with paediatric chronic kidney disease (CKD) visiting haemodialysis care unit of a tertiary hospital Delhi, India. Materials and Methods: A prospective observational study, which the study subjects were recruited from patients availing facility dialysis at centre Delhi The authors 50 who met inclusion criteria. Child Depression Inventory (CDI) questionnaire was administered to language they could easily understand by use...
Aggregation-induced-emission luminogens (AIEgens) have gained considerable attention as interesting tools for several biomedical applications, especially bioimaging due to their brightness and photostability. Numerous AIEgens been developed lighting up the subcellular organelles understand forms functions not only healthy but also unhealthy states, such in cancer cells. However, there is lack of easily synthesizable, biocompatible small molecules illuminating mitochondria (powerhouses)...
The presence of the same proteins at different sub-cellular locations with completely functions adds to complexity signalling pathways in cancer.
Graphene oxide based self-assembled nanoparticles were developed to target the endoplasmic reticulum (ER) induce ER stress in cancer cells.
NMR spectroscopy combined with MD simulation and electronic structure calculations enabled us to quantify the energetics of intermolecular n → π* interaction carbon-bonding (n σ* interaction) in solution.
Mitochondrial dysfunction is implicated in myriad diseases, including cancer.
India contributes close to 20% of the global cervical cancer burden. This article reviews preventive strategies against and suggest a few way forward for prevention in India. A literature review online databases (Embase, Google Scholar, PubMed, Scopus) reports from government websites regarding HPV vaccination was conducted. Currently, four different vaccines are available India: bivalent vaccine, nonavalent vaccine two quadrivalent vaccines. To reduce India’s burden, National Technical...
The discovery of exogenous contrast agents (CAs) is one the key factors behind success and widespread acceptability MRI as an imaging tool. To long list CAs, newest addition chemical exchange saturation transfer (CEST)-based CAs. Among them, diaCEST CAs are safer metal-free option constituted by a large pool organic macromolecules, but tradeoff comes in terms smaller natural offset. Another major challenge for CEST that they need to operate tens millimolar concentration range produce any...
In recent years, antibiotics have emerged as alternative medicines in cancer therapy due to their capability of mitochondrial dysfunction cells. However, render collateral damage noncancerous cells by targeting transcription and translational machinery. To address this, herein, we engineered three different mitochondria-targeted cationic antibiotic (tigecycline)-loaded nanoparticles from cholesterol conjugates. Dynamic light scattering electron microscopy confirmed the spherical morphology a...
Sulfononylhydrazide-hydrazone based small molecules as ER stress modulators for anti-cancer therapy
Navigation and obstacle avoidance are one of the most important tasks for any mobile robot. This article proposes design implementation a hybrid fuzzy (H-fuzzy) architecture intelligent navigation robot in static dynamic environments. The proposed H-fuzzy is combination Takagi-Sugeno type Mamdani-type logics, which helps to reach goal with avoidance. logic (TFa) used assist goal. inputs distances received from group sensors, output turning angle between (MFa) integrated TFa control motor...
A healthy state of life suggests not only a disease-free condition but also normal psychological functioning and behaviour. To maintain life, the duration light exposure is crucial factor. Perturbation standard light-dark cycle (LD: 12 h light-12 dark in mice) may result brain, behavioural physiological abnormalities. The current study determined effects 3 5 weeks constant darkness (DD: 00 light-24 dark) on behaviour, hormones, prefrontal cortex (PFC) metabolome male female C57BL/6 J mice....
Abstract Endoplasmic reticulum (ER) is highly critical for the sub‐cellular protein synthesis, post‐translational modifications and myriads of signalling pathways to maintain cellular homeostasis. Consequently, dysregulation in ER functions leads stress different pathological situations including cancer. Hence, exploring small molecules induce emerged as one unorthodox strategies future cancer therapeutics. However, development targeted novel remains elusive due dearth targeting moieties....
A comparison of different diacetamide isomers shows the influence hydrogen-bonding networks in tuning diaCEST MRI contrast efficiency.
In the present study, fungi were isolated and screened from barren land in south-eastern Coalfields limited (SECL) Chhattisgarh, India. Out of 14 fungi, only three fungal isolates exhibited pigmentation screening studies. The strain SP1 highest pigmentation, which was further utilized for vivo production, purification, characterization melanin pigment. physical chemical properties pigment showed insolubility organic solvents water, solubility alkali, precipitation acid, decolorization with...
It is often perceived that craft means no technology, primitive methods, and materials have zero or significantly less impact on the actual needs of people. However, this research trying to trace craft's nature, importance, potential in creating human-centric designs with sustainable methods. This discusses role design for a future. The intent build bridge between design, craft, sustainability. paper hopes bring together all three benefit participating stakeholders, researchers, designers,...
Abstract Tauopathies, including Alzheimer’s disease (AD), comprise microtubule-associated protein tau aggregates that cause neuronal cell death and clinical cognitive decline. Reducing overall abundance remains a central strategy for therapeutics; however, no disease-modifying treatment exists to date. One principal pathway balancing cellular proteostasis includes the mechanistic target of rapamycin complex 1 (mTORC1) signaling. Recently, arginine emerged as one primary amino acids activate...
Seasonal incidence of mustard insect pests and their correlation with weather parameters during Rabi, 2021-22 revealed that aphid [Lipaphis erysimi (Kalt.)],infestation began from 51 st standard meteorological week (SMW) reached at peak (126.20 10 cm -1 terminal shoot) on 4 th SMW while the painted bug, Bagrada hilaris (Kirk.)infestation was observed twice cropping season.First infestation recorded in 45 (0.60 bugs plant ) second occurred 8 to (5.13 ).The activity flea beetle, Phyllotreta...