A5063895403- Receptor Mechanisms and Signaling
- Neuropeptides and Animal Physiology
- Nicotinic Acetylcholine Receptors Study
- Neurotransmitter Receptor Influence on Behavior
- Neuroendocrine regulation and behavior
- Stress Responses and Cortisol
- Health and Lifestyle Studies
- Behavioral Health and Interventions
- Smoking Behavior and Cessation
- Obesity, Physical Activity, Diet
- Pain Mechanisms and Treatments
- Neuroscience of respiration and sleep
- Media Influence and Health
University of Surrey
2010-2020
The prevalence of smoking in schizophrenia patients is exceptionally high; it not known why but many researchers suggest that constitutes a form self-medication. Among the symptoms may be improved by nicotine are cognitive deficits. Hence, we studied effects long-term administration on cognition genetic animal model susceptibility, G72-transgenic (G72Tg) mice.
Abstract There is growing agreement that genetic factors play an important role in the risk to develop heroin addiction, and comparisons of addiction vulnerability inbred strains mice could provide useful information on question individual addiction. This study examined rewarding locomotor‐stimulating effects male C57BL/6J DBA/2J mice. Heroin induced locomotion sensitisation but not developed conditioned place preference (CPP) highest doses heroin, while showed CPP only lowest doses,...
Background and Purpose Evidence suggests that exercise decreases nicotine withdrawal symptoms in humans; however, the mechanisms mediating this effect are unclear. We investigated, a mouse model, of intensity during chronic exposure on severity, binding α4β2*, α7 nicotinic acetylcholine (nAChR), μ‐opioid (μ receptors) D 2 dopamine receptors brain‐derived neurotrophic factor (BDNF) plasma corticosterone levels. Experimental Approach Male C57Bl/6J mice treated with (minipump, 24 mg·kg −1 ·day...
Nicotine dependence and schizophrenia are two mental health disorders with remarkably high comorbidity. Cigarette smoking is particularly prevalent amongst schizophrenic patients it hypothesised to comprise a form of self-medication for relieving cognitive deficits in these patients. Emerging evidence suggests role the neurohypophysial peptide oxytocin modulation drug addiction, as well symptomology; however, underlying mechanism remains unclear. Therefore, we sought investigate effects...
The primary aim of this study was to assess the effectiveness a short bout (10 min) moderate-intensity exercise reduce withdrawal symptomatology, craving and negative affect; while secondary how moderate can be modulated by perception intensity in physically active low-activity smokers. Fifty smokers were recruited (24 male 26 female) randomized three different conditions. Prescribed (objective) (OBJ) perceived (PER), passive waiting (PW). After intervention (T3), reported less desire smoke...
1. If You Pay, Will They Come? Evaluating the Impact of Subsidies on Cessation Outcomes in Walk or Run to Quit Program Kelly Wunderlich, Daniel Do, Hannah Martin, Carly Priebe, Guy Faulkner, Kenneth Ward Journal Smoking CrossRef