Axel Hofmann

ORCID: 0000-0003-0615-7474
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About
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Research Areas
  • Blood transfusion and management
  • Blood donation and transfusion practices
  • Trauma, Hemostasis, Coagulopathy, Resuscitation
  • Erythropoietin and Anemia Treatment
  • Hemoglobinopathies and Related Disorders
  • Venous Thromboembolism Diagnosis and Management
  • Trauma and Emergency Care Studies
  • Iron Metabolism and Disorders
  • Artificial Intelligence in Healthcare and Education
  • Hyperglycemia and glycemic control in critically ill and hospitalized patients
  • Medical and Health Sciences Research
  • Machine Learning in Healthcare
  • Cardiac, Anesthesia and Surgical Outcomes
  • Pancreatic and Hepatic Oncology Research
  • Hemoglobin structure and function
  • Erythrocyte Function and Pathophysiology
  • Public Administration and Political Analysis
  • Organ Donation and Transplantation
  • Healthcare cost, quality, practices
  • Head and Neck Cancer Studies
  • Digital Innovation in Industries
  • Shoulder Injury and Treatment
  • Sepsis Diagnosis and Treatment
  • Dialysis and Renal Disease Management
  • Forensic Toxicology and Drug Analysis

The University of Western Australia
2016-2025

University Hospital of Zurich
2013-2023

University of Zurich
1990-2023

Kepler Universitätsklinikum
2018-2022

Curtin University
2011-2022

University Hospital Centre Zagreb
2022

Ente Ospedaliero Cantonale
2022

Università della Svizzera italiana
2022

Bentley (Germany)
2022

Englewood Hospital and Medical Center
2007-2021

Blood utilization has long been suspected to consume more health care resources than previously reported. Incomplete accounting for blood costs the potential misdirect programmatic decision making by systems. Determining cost of supplying patients with transfusions requires an in-depth examination complex array activities surrounding transfuse.To accurately determine in a surgical population from system perspective, activity-based costing (ABC) model was constructed. Tasks and resource...

10.1111/j.1537-2995.2009.02518.x article EN Transfusion 2009-12-09

BACKGROUND Patient blood management (PBM) programs are associated with improved patient outcomes, reduced transfusions and costs. In 2008, the Western Australia Department of Health initiated a comprehensive health‐system–wide PBM program. This study assesses program outcomes. STUDY DESIGN AND METHODS was retrospective 605,046 patients admitted to four major adult tertiary‐care hospitals between July 2008 June 2014. Outcome measures were red cell (RBC), fresh‐frozen plasma (FFP), platelet...

10.1111/trf.14006 article EN cc-by-nc-nd Transfusion 2017-02-02

Benchmarking transfusion activity may help to eliminate inappropriate use of blood products. The goal this study was measure and compare the current practice identify predictors in public hospitals develop strategies optimize practices.This a prospective observational 18 randomly selected from April 2004 February 2005. Primary outcome measures were amount intra- postoperative components transfused intercenter variability rate. Secondary prevalence preoperative anemia, calculated...

10.1111/j.1537-2995.2007.01286.x article EN Transfusion 2007-06-07

Preoperative anaemia is common in patients undergoing orthopaedic and other major surgery. Anaemia associated with increased risks of postoperative mortality morbidity, infectious complications, prolonged hospitalization, a greater likelihood allogeneic red blood cell (RBC) transfusion. Evidence the clinical economic disadvantages RBC transfusion treating perioperative has prompted recommendations for its restriction growing interest approaches that rely on patients' own (rather than donor)...

10.1093/bja/aes139 article EN cc-by-nc British Journal of Anaesthesia 2012-05-29

Anaemia and iron deficiency (ID) are frequent complications in patients with solid tumours or haematological malignancies, particularly treated chemotherapeutic agents [1.Ludwig H. Van Belle S. Barrett-Lee P. The European Cancer Survey (ECAS): a large, multinational, prospective survey defining the prevalence, incidence, treatment of anaemia cancer patients.Eur J Cancer. 2004; 40: 2293-2306http://dx.doi.org/10.1016/j.ejca.2004.06.019Abstract Full Text PDF PubMed Scopus (614) Google Scholar,...

10.1093/annonc/mdx758 article EN publisher-specific-oa Annals of Oncology 2017-11-23

While patient blood management (PBM) initiatives are increasingly adopted across the globe as part of standard care, there is need for a clear and widely accepted definition PBM. To address this, an expert group representing PBM organizations from International Foundation Patient Blood Management (IFPBM), Network Advancement Management, Haemostasis Thrombosis (NATA), Society (SABM), Western Australia (WAPBM) Group, OnTrac (Ontario Nurse Transfusion Coordinators) convened developed this...

10.1213/ane.0000000000005873 article EN Anesthesia & Analgesia 2022-02-10

Background: Perioperative anemia has been associated with increased risk of red blood cell transfusion and morbidity mortality after surgery. The optimal approach to the diagnosis management perioperative is not fully established. Objective: To develop consensus recommendations for in surgical patients. Methods: An international expert panel reviewed current evidence developed using modified RAND Delphi methodology. Results: recommends that all patients except those undergoing minor...

10.1097/sla.0000000000005721 article EN cc-by-nc-nd Annals of Surgery 2022-09-21

Farmer, Shannon L. DHSc; Ellis, Carleen MEd; Hamdorf, Jeffrey M. MD; Falconer, Darren PhD; Symons, Kylie BNsg; McNally, Claire MNsg; Monk, Angie RM, RN; Leahy, Michael F. MBChB; McDonnell, Nolan Hofmann, Axel Dr rer medic Author Information

10.1213/ane.0000000000007364 article EN Anesthesia & Analgesia 2025-01-28

Background: Studies of traumatic knee dislocations have failed to provide a consensus regarding the best method treatment. Purpose: Our purpose was evaluate results after surgical repair or reconstruction versus nonsurgical treatment and compare influence prognostic factors. Study Design: Retrospective study. Methods: Eighty-nine patients were treated for dislocation. Surgical cruciate ligaments performed in 63 (repair, 49; reconstruction, 14). In 26 patients, undertaken. Results: At an...

10.1177/03635465020300051601 article EN The American Journal of Sports Medicine 2002-09-01

Background The aim of this study was to investigate the impact introduction a patient blood management ( PBM ) program in cardiac surgery on transfusion incidence and outcome. Study Design Methods Clinical data were compared between pre‐ epoch J uly 2006‐ M arch 2007) A pril 2007‐ S eptember 2012). Results There total 2662 patients analyzed, 387 2275 epoch. Red cell RBC loss decreased from mean (± SD 810 ± 426 mL (median, 721 605 369 552 ; p < 0.001) pretransfusion hemoglobin 7.2 1.4 6.6...

10.1111/trf.12946 article EN Transfusion 2015-01-06

Abstract The objective of this paper is to introduce clinicians and health care professionals the concept patient blood management (PBM) explain difference between PBM “appropriate use” products. five reasons why modern systems need shift from product-focused transfusion practice are also presented. These are: aging population with a leveraged demand for products opposed shrinking donor base; growing awareness that complex service involving many different cost centers within hospital...

10.1634/theoncologist.2011-s3-3 article EN The Oncologist 2011-02-09
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