- Dementia and Cognitive Impairment Research
- Alzheimer's disease research and treatments
- Attention Deficit Hyperactivity Disorder
- Action Observation and Synchronization
- Diet and metabolism studies
- Cholinesterase and Neurodegenerative Diseases
- Child Nutrition and Feeding Issues
- Child Nutrition and Water Access
- Birth, Development, and Health
- Clinical Reasoning and Diagnostic Skills
- Infant Development and Preterm Care
- Educational and Psychological Assessments
- Machine Learning in Healthcare
- Child and Adolescent Health
- Venomous Animal Envenomation and Studies
- Sex and Gender in Healthcare
- Cognitive Abilities and Testing
- Nutrition, Genetics, and Disease
- Embodied and Extended Cognition
- Cardiac electrophysiology and arrhythmias
- Autism Spectrum Disorder Research
- Children's Physical and Motor Development
- Health Systems, Economic Evaluations, Quality of Life
- Resilience and Mental Health
- Gender Roles and Identity Studies
Columbia University
2018-2025
Columbia University Irving Medical Center
2024
The Neurological Institute
2022
Cornell University
2015-2018
Weill Cornell Medicine
2016-2018
Like virtually all age-related chronic diseases, late-onset Alzheimer's disease (AD) develops over an extended preclinical period and is associated with modifiable lifestyle environmental factors. We hypothesize that multimodal interventions address many risk factors simultaneously are individually tailored to patients may help reduce AD risk. describe a novel clinical methodology used evaluate treat at two Prevention Clinics. The framework applies evidence-based principles of precision...
Multidomain intervention for Alzheimer's disease (AD) risk reduction is an emerging therapeutic paradigm.Patients were prescribed individually tailored interventions (education/pharmacologic/nonpharmacologic) and rated on compliance. Normal cognition/subjective cognitive decline/preclinical AD was classified as Prevention. Mild impairment due to AD/mild-AD Early Treatment. Change from baseline 18 months the modified Prevention Cognitive Composite (primary outcome) compared against matched...
While many theories focus on consciousness as a feature of individual brains, some instead situate it in social context an adaptation for the cognitive demands human group life. Though these approaches to provide evolutionarily compelling and parsimonious account its origins, is less clear how basis affects phenomenological details everyday experience. In this paper, I address gap by merging with sensorimotor accounts perceptual experience, arguing that certain core qualitative features...
This study aims to automate the prediction of Mini-Mental State Examination (MMSE) scores, a widely adopted standard for cognitive assessment in patients with Alzheimer's disease, using natural language processing (NLP) and machine learning (ML) on structured unstructured EHR data.
The shift to videoconferencing since the start of Covid-19 pandemic has transformed medical education. But loss many nonverbal cues during Internet-based interactions could affect learning.
Assess effectiveness of multi-modal interventions on Alzheimer's disease (AD), dementia, and vascular risk scales. Secondary outcomes include overall differential blood biomarkers cognition (based genotype physician/patient reported adherence).
This clinical trial investigated the comparative effectiveness of multidomain precision medicine interventions in patients at-risk for Alzheimer's disease (AD) dementia. Patients aged 25–86 were recruited from an AD prevention clinic and classified according to baseline characteristics. with normal cognition, subjective cognitive decline preclinical as Prevention participants, while mild impairment (MCI) due Early Treatment participants. Each participant was prescribed individualized rated...