Tim Cross

ORCID: 0000-0003-0625-8726
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About
Contact & Profiles
Research Areas
  • Liver Disease Diagnosis and Treatment
  • Hepatocellular Carcinoma Treatment and Prognosis
  • Liver Disease and Transplantation
  • COVID-19 Clinical Research Studies
  • Cholangiocarcinoma and Gallbladder Cancer Studies
  • Long-Term Effects of COVID-19
  • SARS-CoV-2 and COVID-19 Research
  • Organ Transplantation Techniques and Outcomes
  • Intensive Care Unit Cognitive Disorders
  • Liver Diseases and Immunity
  • Advanced Radiotherapy Techniques
  • Hepatitis B Virus Studies
  • Clinical practice guidelines implementation
  • Cancer, Lipids, and Metabolism
  • Cancer Diagnosis and Treatment
  • Hepatitis C virus research
  • Global Cancer Incidence and Screening
  • Respiratory Support and Mechanisms
  • Alcohol Consumption and Health Effects
  • Folate and B Vitamins Research
  • Drug-Induced Hepatotoxicity and Protection
  • Radiomics and Machine Learning in Medical Imaging
  • Pharmaceutical Quality and Counterfeiting
  • Management of metastatic bone disease
  • Coronary Artery Anomalies

University of Liverpool
2014-2024

Aintree University Hospitals NHS Foundation Trust
2021-2024

Royal Liverpool University Hospital
2014-2023

Informa Healthcare
2018-2023

London Bridge Hospital
2021

Royal Liverpool and Broadgreen University Hospital NHS Trust
2014-2019

Liverpool Hospital
2014-2017

HCA International Foundation
2016

Derriford Hospital
2010-2011

Whittington Hospital
2007

The incidence of primary liver cancer (PLC) is increasing in Western Europe. To understand trends over time and the current burden UK, a detailed analysis epidemiology PLC its subtypes was conducted.Data on PLCs diagnosed during 1997-2017 were obtained from population-based, nationwide registries UK. European age-standardised (ASR) incidence-based mortality rates (ASMR) per 100,000 person-years calculated overall by sex UK-nation. Annual percentage change estimated using Joinpoint...

10.1016/j.jhepr.2021.100232 article EN cc-by JHEP Reports 2021-01-19

Liver transplantation (LT) is a lifesaving treatment. Because of the shortage donor organs, some patients will not survive long enough to receive transplant. The identification LT candidates at increased risk short-term mortality without may affect listing decisions. Functional capacity, determined with cardiopulmonary exercise testing (CPET), measure cardiorespiratory reserve and predicts perioperative outcomes. This study examined association between functional capacity survival before...

10.1002/lt.23907 article EN Liver Transplantation 2014-05-08

Abstract Background Hepatocellular carcinoma (HCC) incidence has increased rapidly, and prognosis remains poor. We aimed to explore predictors of routes diagnosis (RtD), outcomes, in HCC cases. Methods cases diagnosed 2006–2017 were identified from the National Cancer Registration Dataset linked Hospital Episode Statistics RtD metric. Multivariable logistic regression was used associations between RtD, year, 365-day mortality receipt potentially curative treatment. Results 23,555 identified;...

10.1038/s41416-024-02645-3 article EN cc-by British Journal of Cancer 2024-03-18

Abstract Background Hepatocellular carcinoma (HCC) incidence, management and survival across England were examined to determine if geographical inequalities exist. Method 15,468 HCC cases diagnosed 2010–2016 included. Age-standardised incidence rates, net proportions receiving potentially curative treatment presenting through each route diagnosis adjusted for age at diagnosis, sex area-based deprivation quintile, calculated overall by Cancer Alliance. Results rates increased in men from 6.2...

10.1038/s41416-021-01509-4 article EN cc-by British Journal of Cancer 2021-11-26

Objectives Outcomes in hepatocellular carcinoma (HCC) are determined by both cancer characteristics and liver disease severity. This study aims to validate the use of inpatient electronic health records determine severity from treatment procedure codes. Design Retrospective observational study. Setting Two National Health Service (NHS) centres England. Participants 339 patients with a new diagnosis HCC between 2007 2016. Main outcome Using records, we have developed an optimised algorithm...

10.1136/bmjopen-2018-028571 article EN cc-by-nc BMJ Open 2019-07-01

Abstract Background Many people now seek alternative methods of weight loss. The internet provides a readily available source reduction products, the ingredients which are often unclear. authors describe case acute hepatitis in 20 year old woman caused by such product purchased over internet. Case Presentation A 20-year presented with two day history abdominal pain, vomiting and jaundice. There were no identifiable risk factors for chronic liver disease. Liver function tests demonstrated an...

10.1186/1475-2891-6-13 article EN cc-by Nutrition Journal 2007-06-27

<h3>Introduction</h3> Liver size may be important in prognostication cirrhosis. The LAAR score has previously shown a relationship between liver and survival but is hampered by subjectivity. current study aimed to improve the existing score. <h3>Methods</h3> A retrospective-prospective cohort was performed on patients with censor point used date of patient death or transplant (LT) from CT date. Time points were measured scan last clinic appointment. enhanced Liver<sup>pool</sup> Abdomen Area...

10.1136/gutjnl-2014-307263.209 article EN Gut 2014-06-01

<h3>Introduction and Aims</h3> The healthcare industry has a substantial carbon footprint the recent 2022 Health Care Act committed NHS to net zero by 2040. In 2022, BASL published its Sustainability Strategy reduce Association's footprint. sustainability of different ways presenting posters is not known. aim this study was, therefore, analyse compare three options organising displaying during annual conference. <h3>Methods</h3> A comparative analysis models poster display was performed...

10.1136/gutjnl-2023-basl.150 article EN Poster presentations 2023-09-01

Postoperative pulmonary complications and mortality rates during the COVID-19 pandemic have been higher than expected, leading to mass cancellation of elective operating in UK. To minimise this, Guy's St Thomas' Hospital NHS Foundation Trust surgery hub executive team at London Bridge (LBH) created an framework LBH, a minimal site, which patients self-isolated for two weeks proceeded with only following negative preoperative SARS-CoV-2 polymerase chain reaction swab. The aim was determine...

10.1308/rcsann.2020.7072 article EN Annals of The Royal College of Surgeons of England 2021-05-06

<h3>Introduction</h3> Non-alcoholic fatty liver disease (NAFLD) is rapidly emerging as a leading cause of hepatocellular carcinoma (HCC) driven by the dual obesity and type 2 diabetes (T2D) epidemics. <h3>Aim</h3> To compare frequencies HCC detected outside surveillance for people with NAFLD vs. other aetiologies to examine possible underlying reasons this impact on survival. <h3>Methods</h3> A cross-sectional study patients across one large NHS hospital trust was performed. Data extracted...

10.1136/gutjnl-2022-basl.72 article EN Abstracts 2022-09-01
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