A5051930868- Algal biology and biofuel production
- Respiratory viral infections research
- Photosynthetic Processes and Mechanisms
- SARS-CoV-2 detection and testing
- SARS-CoV-2 and COVID-19 Research
- Influenza Virus Research Studies
- Virus-based gene therapy research
- Biofuel production and bioconversion
- COVID-19 Clinical Research Studies
- Viral gastroenteritis research and epidemiology
- Microbial Metabolic Engineering and Bioproduction
- Neonatal Respiratory Health Research
- Marine and coastal ecosystems
- Photoreceptor and optogenetics research
- Hemoglobin structure and function
- Polyomavirus and related diseases
- Parvovirus B19 Infection Studies
- Fungal and yeast genetics research
- Herpesvirus Infections and Treatments
- Global Energy and Sustainability Research
- Plant nutrient uptake and metabolism
- Congenital Diaphragmatic Hernia Studies
- Data-Driven Disease Surveillance
- RNA and protein synthesis mechanisms
- Animal Virus Infections Studies
Arizona State University
2021-2024
Tohoku University Hospital
2022
Tohoku University
2022
Omron (Japan)
2022
Maricopa County Department of Public Health
2022
Oklahoma State University
2014-2018
Oklahoma State University Oklahoma City
2013
The 2023-24 U.S. influenza season was characterized by a predominance of A(H1N1)pdm09 virus circulation with co-circulation A(H3N2) and B/Victoria viruses. We estimated vaccine effectiveness (VE) in the United States against mild-to-moderate medically attended illness season. enrolled outpatients aged ≥8 months acute respiratory 7 states. Respiratory specimens were tested for type/subtype reverse-transcriptase polymerase chain reaction (RT-PCR). Influenza VE test-negative design comparing...
SARS-CoV-2 continues to evolve new variants throughout the pandemic. However, temporal dynamics of how emerge become dominant circulating variant is not precisely known.
Canine distemper virus (CDV) is a highly contagious that causes multisystemic disease in dogs. We received seven samples from dogs with CD the United States during 2007. CDV isolates these formed large, multinucleated syncytia Vero cell line expressing canine signaling lymphocyte activation molecule (SLAM). Based on hemagglutinin gene sequences, three states (California, Missouri, and Oklahoma) two genetic groups: group I (major; six of isolates) consisted closely related to European...
As the SARS-CoV-2 virus evolves, mutations may result in diminished sensitivity to qRT-PCR diagnostic assays. We investigated four polymorphisms circulating Delta lineage that N gene target failure (NGTF) on TaqPath COVID-19 Combo Kit. These were detected from genome sequences matched with assay results of saliva specimens. Full length genes samples displaying NGTF cloned into plasmids and assayed using three constructs resulted reduced Kit compared controls (mean Ct differences 3.06, 7.70,...
Areas of dense population congregation are prone to experience respiratory virus outbreaks. We monitored wastewater and clinic patients for the presence viruses on a large, public university campus. Campus sewer systems were in 16 locations using next generation sequencing over 22 weeks 2023. During this period, we detected surge human adenovirus (HAdV) levels wastewater. Hence, initiated clinical surveillance at an on-campus from presenting with acute infection. From whole genome 123 throat...
Influenza viruses are constantly evolving and therefore monitored worldwide in the hope to reduce burden of disease by annual updates vaccine recommendations. We conducted genomic sequencing 110 influenza A 30 B from specimens collected between October 2023 February 2024 Arizona, USA. identified mutations hemagglutinin (HA) antigenic sites as well neuraminidase (NA) gene our samples. also found no unique HA NA vaccinated yet influenza-infected individuals. Real-time surveillance is important...
As severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) continues to evolve, mutations arise that will allow the virus evade immune defenses and therapeutics. Assays can identify these be used guide personalized patient treatment plans. Digital PCR (dPCR) is a fast reliable complement whole-genome sequencing discriminate single nucleotide polymorphisms (SNPs) in template molecules. Here, we developed panel of SARS-CoV-2 dPCR assays demonstrate its applications for typing variant...
Abstract We conducted genomic sequencing of 110 influenza A and 30 B viruses from specimens collected between October 2023 February 2024 in Arizona, USA. identified mutations the hemagglutinin (HA) antigenic sites. Real-time surveillance is important to ensure vaccine effectiveness.
Cellular import of D-xylose, the second most abundant sugar in typical lignocellulosic biomass, has been evidenced to be an energy-depriving process bacterial biocatalysts. The facilitator Zymomonas mobilis, Glf, is capable importing xylose at high rates without extra energy input, but inhibited by D-glucose (the primary biomass sugar), potentially limiting utility this transporter for fermentation mixtures derived from lignocellulose. In work we developed Escherichia coli platform strain...
Abstract We investigated a university-affiliated cohort of SARS-CoV-2 Omicron BA.2 infections in Arizona, USA. Of 44 cases, 43 were among students; 26 persons symptomatic, 8 sought medical care, but none hospitalized. Most (55%) had completed primary vaccine series; received booster vaccines. infection was mild this young cohort.
Abstract We conducted Respiratory Syncytial Virus (RSV) genomic sequencing surveillance of 100 RSV-A and 27 RSV-B specimens collected between November 2022 April 2023 in Arizona, USA. identified mutations the pre-fusion F protein antigenic sites both RSV-B. Continued will be important to ensure RSV vaccine effectiveness.
The nasopharynx and its microbiota are implicated in respiratory health disease. interplay between viral infection the nasopharyngeal microbiome is an area of increased interest clinical relevance. impact SARS-CoV-2, etiological agent Coronavirus Disease 2019 (COVID-19) pandemic, on microbiome, particularly among individuals living with HIV, not fully characterized. Here we describe before, during after SARS-CoV-2 a longitudinal cohort Kenyan women (21 HIV 14 HIV-uninfected) their infants...
Areas of dense population congregation are prone to experience respiratory virus outbreaks. We monitored wastewater and clinic patients for the presence viruses on a large, public university campus. Campus sewer systems were in 16 locations using next generation sequencing over 22 weeks 2023. During this period, we detected surge human adenovirus (HAdV) levels wastewater. Hence, initiated clinical surveillance at an on-campus from presenting with acute infection. From whole genome 123 throat...
Quantification of cyanobacterial CO
Abstract Quantification of CO 2 fixation rates by cyanobacteria is vital to determining their potential as industrial strains in a circular bioeconomy. Currently, however, are most often determined through indirect and/or low-resolution methods, resulting an incomplete picture both dynamic behaviors and total carbon fixing potential. To address this, we developed novel, low-cost system for situ off-gas analysis which supports the automated acquisition high-resolution uptake from...
ABSTRACT We identified and characterized seven anellovirus genome sequences in the female genital tract through virome metagenomic sequencing of cervicovaginal lavage specimens from women living with HIV Peru. Phylogenetic genomic analyses indicate that they belong to three newly proposed Lamedtorquevirus , Memtorquevirus Samektorquevirus genera Anelloviridae family.
ABSTRACT As SARS-CoV-2 continues to evolve, mutations arise that will allow the virus evade immune defenses and therapeutics. Assays can identify these be used guide personalized patient treatment plans. Digital PCR (dPCR) is a fast reliable complement whole genome sequencing discriminate single nucleotide polymorphisms (SNPs) in template molecules. Here, we developed panel of dPCR assays demonstrate its applications for typing variant lineages therapeutic monoclonal antibody resistance. We...