Melanie Engels

ORCID: 0000-0003-0661-7426
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About
Contact & Profiles
Research Areas
  • Prenatal Screening and Diagnostics
  • Assisted Reproductive Technology and Twin Pregnancy
  • Ectopic Pregnancy Diagnosis and Management
  • Parvovirus B19 Infection Studies
  • Fetal and Pediatric Neurological Disorders
  • Dental Education, Practice, Research
  • Libraries and Information Services
  • Health and Medical Studies
  • Pregnancy and preeclampsia studies
  • Congenital Anomalies and Fetal Surgery
  • Cardiovascular Issues in Pregnancy
  • Congenital Diaphragmatic Hernia Studies
  • Dental Health and Care Utilization
  • 3D Modeling in Geospatial Applications
  • Lanthanide and Transition Metal Complexes
  • Tumors and Oncological Cases
  • Clinical practice guidelines implementation
  • Personal Information Management and User Behavior
  • Environmental Education and Sustainability
  • Cerebral Venous Sinus Thrombosis
  • Intracranial Aneurysms: Treatment and Complications
  • Image Processing and 3D Reconstruction
  • Global Healthcare and Medical Tourism
  • Neonatal Respiratory Health Research
  • Teratomas and Epidermoid Cysts

Wageningen University & Research
2025

Echo Pharmaceuticals (Netherlands)
2021

Amsterdam University Medical Centers
2020

Amsterdam UMC Location Vrije Universiteit Amsterdam
2003-2015

OLVG
2015

Amsterdam UMC Location University of Amsterdam
2015

Radboud University Medical Center
2015

Leiden University Medical Center
2015

Radboud University Nijmegen
2015

University Medical Center Utrecht
2015

Food and nutrition programmes at secondary schools have the potential to improve public planetary health, as they target a wide range of adolescents. Nevertheless, it is currently unclear what mechanisms are underlying such educational interventions in order aim for behaviour change. This qualitative study therefore aims identify determinants change techniques (BCTs) incorporated school-based food programmes. Better understanding BCTs can points improvements facilitate long-term dietary...

10.1186/s12889-025-22155-y article EN cc-by-nc-nd BMC Public Health 2025-03-25

What are the pregnancy outcomes for women with a twin that is reduced to singleton pregnancy?Fetal reduction of significantly improves gestational age at birth and neonatal birthweight, however an increased risk loss preterm delivery.Women multiple delivery. Fetal can be considered in these women.Retrospective cohort study 118 between 2000 2010.We compared outcome consecutive dichorionic was managed expectantly primary pregnancy. Reductions were performed 10-23(6/7) weeks' gestation by...

10.1093/humrep/dev132 article EN Human Reproduction 2015-06-20

Objectives To construct reference intervals for fetal lung volumes measured longitudinally using three-dimensional (3D) ultrasound, and to evaluate the effect of gender on size. Methods This was a prospective, longitudinal study in obstetric outpatient department VU University Medical Center, Amsterdam. Seventy-eight women with uncomplicated pregnancies were scanned three four times at gestational ages 18–34 weeks. 3D models constructed ultrasound machine's software. After infants delivered...

10.1002/uog.2672 article EN Ultrasound in Obstetrics and Gynecology 2006-01-01

Abstract Objective To evaluate marker distribution of free β‐human chorionic gonadotrophin (fβ‐hCG) and pregnancy‐associated plasma protein‐A (PAPP‐A) in singleton pregnancies conceived by assisted reproduction techniques (ART). Methods In vitro fertilization (IVF) ( n = 203) intracytoplasmic sperm injection (ICSI) 192) cases from a database 14 645 first‐trimester combined tests (overall study group) were selected matched to 1164 controls for gestational age at sample date maternal age....

10.1002/pd.2495 article EN Prenatal Diagnosis 2010-03-11

To study the pregnancy outcomes of women with a dichorionic triamniotic triplet that was reduced to singleton and review literature.We performed nationwide retrospective cohort study. We compared time delivery perinatal mortality in pregnancies singletons ongoing primary pregnancies. Additionally, we reviewed literature on subject.We studied 46 42 an pregnancy. Median gestational age at 38.7 vs. 32.8 weeks, respectively (p < 0.001). Delivery <24 weeks occurred 9 (19.6%) 4 (9.5%) = 0.19)....

10.1159/000441650 article EN Fetal Diagnosis and Therapy 2015-12-17

The Dutch Centre for Population Research has specified quality demands nuchal translucency (NT) measurement in Netherlands. We performed an analysis of the NT 2005-2006 and its influence on screening performance.This was a retrospective study records measurements (n = 27,738) obtained between January 2005 December 2006 retrieved from National Institute Public Health Environment (RIVM). performance each individual operator analyzed with regard to standards, which involved calculation...

10.1002/uog.6398 article EN Ultrasound in Obstetrics and Gynecology 2009-06-26

Objective To evaluate the performance of first‐trimester combined test (FCT) in different maternal age groups and to discuss whether adjustments screening policies should be made. Methods In this retrospective study data ( n = 26 274) from a fetal medicine center on FCT (maternal age, NT, free β‐human chorionic gonadotrophin, pregnancy‐associated plasma protein‐A) were studied. Results 70.6% cases was &lt;36 years 43% Down syndrome (DS) detected group. For women advanced (AMA) (≥36 years)...

10.1002/pd.2873 article EN Prenatal Diagnosis 2011-10-24

&lt;b&gt;&lt;i&gt;Objective:&lt;/i&gt;&lt;/b&gt; To validate previously computed correction factors for free β-human chorionic gonadotrophin (fβ-hCG) and pregnancy-associated plasma protein-A (PAPP-A) in vitro fertilization (IVF) intracytoplasmic sperm injection (ICSI) pregnancies with hormone treatment to determine the effect on false-positive rate (FPR). &lt;b&gt;&lt;i&gt;Methods:&lt;/i&gt;&lt;/b&gt; Retrospective study 249 IVF 250 ICSI cases 20,190 controls. Correction 1.42 (PAPP-A), 1.17...

10.1159/000355527 article EN Fetal Diagnosis and Therapy 2013-01-01

Abstract Objective To describe the prenatal sonographic features and maternal biochemical markers in triploid pregnancies to assess whether phenotype can determine genetic origin. Methods We performed a retrospective multicenter cohort study that included all diagnosed between 2000 2018 two Fetal Medicine Units Amsterdam. growth, presence of structural anomalies, extra‐fetal were retrieved. Asymmetrical intrauterine growth restriction was when head‐to‐abdominal circumference (HC/AC) ratio...

10.1002/pd.5666 article EN cc-by-nc-nd Prenatal Diagnosis 2020-02-10

Background: Increased nuchal translucency (NT) is associated with aneuploidy. When the karyotype normal, fetuses are still at risk for structural anomalies and genetic syndromes. Our study researched diagnostic yield of prenatal microarray in a cohort isolated increased NT (defined as ≥ 3.5 mm) questioned whether useful tool determining adverse outcomes pregnancy. Materials Methods: A prospective was performed, which 166 women, pregnant fetus (ranging from to 14.3 mm mean 5.4 were offered...

10.3389/fmed.2021.737936 article EN cc-by Frontiers in Medicine 2021-10-18

The aim of this study was to compare screening performance for Down syndrome the absolute risk (AR) method first trimester combined test (FCT) at different maternal ages.There a retrospective analysis 32,448 FCT. AR defined as final divided by age risk.The likelihood receiving true prediction comparable between both methods in all groups. With method, two extra cases were detected women <30 years, three missed ≥36 and false decreased overall (OR 0.82, CI 0.77-0.87; P < 0.0001), aged 36-40...

10.1002/pd.4153 article EN Prenatal Diagnosis 2013-05-16

Objective. To describe the cases of 2 fetuses with aneurysms vein Galen diagnosed prenatally. Methods. The techniques used were conventional sonography, three-dimensional and ultrafast magnetic resonance imaging. On basis these imaging modalities, prognostic factors, such as drainage secondary damage, assessed. Results. first fetus had good indices, embolization after birth was successful. According to a poor neonatal outcome predicted for second fetus. neonate died soon birth. Conclusions....

10.7863/jum.2003.22.12.1363 article EN Journal of Ultrasound in Medicine 2003-12-01

The aim of the study was to evaluate a 1 M gadolinium-chelate (gadobutrol) for first-pass MR myocardial perfusion examinations in patients with suspected coronary artery disease (CAD). In phantom studies, signal-to-noise ratio (SNR) and contrast-to-noise (CNR) values gadobutrol were compared gadopentetate (Gd-DTPA). 25 consecutive clinically CAD examined dynamic rest/stress using 0.05 mmol kg−1 gadobutrol. Semi-quantitative evaluation performed by calculating reserve index (MPRI)....

10.1259/bjr/34610669 article EN British Journal of Radiology 2007-11-01

&lt;b&gt;&lt;i&gt;Introduction:&lt;/i&gt;&lt;/b&gt; The objective of this study was to evaluate the performance first-trimester Down syndrome (DS) screening with serum sampling at different weeks gestation. &lt;b&gt;&lt;i&gt;Material and Methods:&lt;/i&gt;&lt;/b&gt; We studied 35,431 singleton pregnancies (2005-2011), including 145 DS cases. Screening determined in maternal age groups between 9 + 0 13 6. &lt;b&gt;&lt;i&gt;Results:&lt;/i&gt;&lt;/b&gt; No significant differences were found...

10.1159/000362186 article EN Fetal Diagnosis and Therapy 2014-01-01

1. Skirton H, Barr O. Influences on uptake of antenatal screening for Down syndrome: A review the literature. Evidence Based Midwifery. 2007;5(1):4-9. Google Scholar

10.18332/ejm/126626 article EN European Journal of Midwifery 2020-09-22

Citations rule the world—at least world of academic medicine. Because importance impact factor, medical journals are dependent on being cited as often possible in other journals. This is also true Deutsches Arzteblatt International, which, after its inclusion Science Citation Index 2009, expecting first factor 2011 (1). In this situation, it easy to forget that citations lay press too important for Being mentioned general media may not enhance but a sign how public deems journal. By...

10.3238/arztebl.2009.0413 article EN Deutsches Ärzteblatt international 2009-06-19

A combined dental and sociological study was completed in Leeuwarden 1976. Approximately 600 children filled a questionnaire were dentally examined. Their mothers also interviewed. 536 took part the study; of these, 45% had full dentures only 33% still normal dentition. These two groups have been compared this article. There very little difference between mean ages groups, but considerable education, family income husband's occupation. Women with used to visit dentist less frequently when...

10.1111/j.1600-0528.1979.tb01221.x article EN Community Dentistry And Oral Epidemiology 1979-08-01

Women with dichorionic twin pregnancies can be faced difficult decisions in the setting of 1 abnormal fetus, caused by hereditary disease, or a chromosomal structural abnormality. Selective feticide is sometimes presented as an option for these women. This technique has been shown to allow pregnancy progress and result birth at least healthy fetus. In this retrospective, multicenter (10 perinatal centers) cohort study that spanned 10 years (2000–2010), authors examined records 118 women...

10.1097/01.ogx.0000473789.30160.4b article EN Obstetrical & Gynecological Survey 2015-12-01
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