A5033086468- Neurological disorders and treatments
- Advanced Neuroimaging Techniques and Applications
- Parkinson's Disease Mechanisms and Treatments
- Functional Brain Connectivity Studies
- Acute Ischemic Stroke Management
- Neural dynamics and brain function
- Health, Environment, Cognitive Aging
- Neuroscience and Neural Engineering
- Advanced MRI Techniques and Applications
- Mental Health Research Topics
- Cerebrovascular and Carotid Artery Diseases
- Genetic Neurodegenerative Diseases
- Advanced Neural Network Applications
- Dementia and Cognitive Impairment Research
- Child Abuse and Trauma
- Cognitive Abilities and Testing
- Software Engineering Research
- Multiple Sclerosis Research Studies
- Neuroscience and Neuropharmacology Research
- Topic Modeling
- Traumatic Brain Injury Research
- Maternal Mental Health During Pregnancy and Postpartum
- Electron Spin Resonance Studies
- Glioma Diagnosis and Treatment
- Spinal Dysraphism and Malformations
Huazhong University of Science and Technology
2021-2025
Tongji Hospital
2021-2025
Nanjing University
2022
To develop a model incorporating radiomic features and clinical factors to accurately predict acute ischemic stroke (AIS) outcomes.Data from 522 AIS patients (382 male [73.2%]; mean age ± standard deviation, 58.9 11.5 years) were randomly divided into the training (n = 311) validation cohorts 211). According modified Rankin Scale (mRS) at 6 months after hospital discharge, prognosis was dichotomized good (mRS ≤ 2) poor > 2); 1310 radiomics extracted diffusion-weighted imaging apparent...
Multiple system atrophy (MSA) and Parkinson's disease (PD) are neurodegenerative disorders characterized by α-synuclein pathology, disrupted iron homeostasis impaired neurochemical transmission. Considering the critical role of in neurotransmitter synthesis transport, our study aims to identify distinct patterns whole-brain accumulation MSA PD, elucidate corresponding substrates.
Heterogeneous MRI manifestations restrict the efficiency and consistency of neuroradiologists in diagnosing hypoxic-ischemic encephalopathy (HIE) due to complex injury patterns. This study aimed develop validate an intelligent HIE identification model (termed as DLCRN, deep learning clinical-radiomics nomogram) based on conventional structural clinical characteristics.In this retrospective case-control study, full-term neonates with healthy controls were collected two different medical...
Anxiety is characterized by altered brain networks. Directional information flows among dynamic networks concerning neuropathogenesis of anxiety have not yet been investigated. The role directional influences between in gene-environment effects on remains to be further elucidated. In a large community sample, this resting-state functional MRI study estimated effective connectivity large-scale based sliding-window approach and Granger causality analysis, providing for signal transmission We...
Gliomas are highly invasive brain tumors that evade accurate geographic assessment by conventional MRI due to microscopic invasion along white matter (WM) tracts. Advanced diffusion techniques needed assess occult WM involvement.
When changing code, developers sometimes neglect updating the related comments, bringing inconsistent or outdated comments. These comments increase cost of program understanding and greatly reduce software maintainability. Researchers have put forward some solutions, such as CUP HEBCUP, which update efficiently for simple code changes (i.e. modifying a single token), but not good enough complex ones. In this paper, we propose an approach, named HatCUP (Hybrid Analysis Attention based Comment...
Background Corticospinal tract (CST) injury has been shown to exert a major influence on functional recovery after ischemic stroke. Purpose To evaluate the prognostic value of CST estimated using recent developed tractometry‐based method. Study Type Prospective. Population Forty‐eight patients with damage induced by stroke lesion who underwent brain magnetic resonance imaging within 7 days from onset. Sequence Diffusion‐weighted ( b = 1000 seconds/mm 2 ) and diffusion kurtosis (DKI)...
Proton exchange rate (kex) magnetic resonance imaging (MRI) has recently been developed, with preliminary results demonstrating its potential for evaluating reactive oxygen species. This prospective cohort study investigated the kex in different stroke stages and correlation severity prognosis.In all, 96 ischemic patients were included study. Patients divided into 3 groups based on phase (acute, subacute, chronic). A spin echo-echo planar sequence presaturation powers of 1.5, 2.5, 3.5 µT was...
Abstract Aging is widely acknowledged as the primary risk factor for brain degeneration, with Parkinson's disease (PD) tending to follow accelerated aging trajectories. We aim investigate impact of structural on temporal dynamics a large‐scale functional network in PD. enrolled 62 PD patients and 32 healthy controls (HCs). The level was determined by calculating global local age gap estimates (G‐brainAGE L‐brainAGE) from images. neural activity whole captured identifying coactivation...
Anxiety is usually attributed to adverse environmental factors, but it known as a polygenic inheritance disease. Gene-environment interactions on the occurrence and severity of anxiety are still unclear. The role brain network connectivity in gene-environment effects has not been explored may be key understanding neuropathogenesis guiding treatment. This study recruited 177 young adults from community that completed functional magnetic resonance imaging, Childhood Trauma Questionnaire (CTQ),...
Ischemic stroke is a major cause of death and disability in China worldwide.Many reasons can stroke, including atherosclerosis, artery embolization, cervical dissection so on.Among them, spontaneous intracerebral rare acute ischemic stroke.Here we present case anterior cerebral (ACA) with occlusion causing infarction, successfully cured by arterial thrombolysis stenting.A 60-year-old man was admitted because stroke.Imaging examination showed that the proximal A2 segment right ACA occluded,...
As an important predictor of adulthood psychopathology, self-reported childhood abuse appears heritable and is associated with brain abnormalities. However, the specific genetic mechanisms behind these alterations remain largely unknown. This study recruited young adults who reported different degrees from community. In order to fully understand influence genes on changes related abuse, various experiments were conducted in this study. Firstly, volume gray matter white investigated by using...