A5006345309- Pregnancy and preeclampsia studies
- Maternal and fetal healthcare
- Ectopic Pregnancy Diagnosis and Management
- Preterm Birth and Chorioamnionitis
- Prenatal Screening and Diagnostics
- Pregnancy-related medical research
- Maternal and Perinatal Health Interventions
- Congenital Heart Disease Studies
- Neonatal and fetal brain pathology
- HER2/EGFR in Cancer Research
- Cardiovascular Issues in Pregnancy
- Fetal and Pediatric Neurological Disorders
- Neonatal Respiratory Health Research
- Intestinal Malrotation and Obstruction Disorders
- Birth, Development, and Health
- Assisted Reproductive Technology and Twin Pregnancy
- Gastrointestinal disorders and treatments
- Uterine Myomas and Treatments
- Pediatric Hepatobiliary Diseases and Treatments
- Monoclonal and Polyclonal Antibodies Research
- Gynecological conditions and treatments
- Systemic Lupus Erythematosus Research
- Estrogen and related hormone effects
- Reproductive System and Pregnancy
- Renal and Vascular Pathologies
Kurume University
2017-2024
Kurume University Hospital
2017
Fukuoka University Hospital
2007-2016
Fukuoka University
2007-2015
Azienda Socio Sanitaria Territoriale Grande Ospedale Metropolitano Niguarda
2011
National Kyushu Medical Center
2002
Cornell University
1999-2001
New York State College of Veterinary Medicine
1999
Kyushu University Hospital
1994-1999
Kyushu University
1990-1994
Objective Assisted reproductive technology (ART), especially frozen–thawed embryo transfer (FET) in a hormone replacement cycle (HRC), is risk factor for placenta accreta spectrum (PAS). This study aimed to clarify the factors PAS related maternal background and ART techniques pregnancies achieved after FET an HRC. Study Design We performed case–control two tertiary perinatal centres Japan. Among 14,028 patients who delivered at ≥24 weeks of gestation or were transferred delivery between...
Pancreatic cancer is one of the most lethal malignancies. Epidermal growth factor receptor (EGFR), HER3, Akt, and amphiregulin have been recognized as targets for pancreatic therapy. Although gemcitabine + erlotinib has recommended chemotherapy cancer, prognosis extremely poor. The development molecularly targeted therapies required patients with cancer. To assess validation a target therapy, we examined its expression in using real‐time PCR analyses ELISA. We also measured apoptotic cell...
Abstract In the present study, we characterized four myometrial contraction-associated proteins (mCAPs): oxytocin receptor (OTR), prostaglandin H synthase 2 (PGHS2), estrogen α (ERα), and heat shock protein 90 (Hsp90) messenger RNA (mRNA) expression in nongravid horn of pregnant sheep compared them with their gravid that is exposed to a greater degree stretch. We also examined regulatory effects progesterone on OTR mRNA ovariectomized nonpregnant sheep. addition, determined ontogeny mCAP...
Pulmonary embolism (PE) is the leading cause of maternal death in developed countries, and prevention venous thromboembolism (VTE) a pivotal part current obstetric care. This study evaluated safety efficacy enoxaparin sodium for thromboprophylaxis after cesarean section (C/S), analyzed risk factors associated with VTE. One hundred forty-three women deemed to be at high postoperative deep vein thrombosis (DVT) were enrolled between January 2011 May 2012 seven institutions Japan. Subcutaneous...
Abstract Aim: To elucidate the clinical significance of progressive cervical length (CL) shortening before 31 weeks' gestation. Methods: Transvaginal ultrasonography was used for longitudinal measurements CL in 114 singletons. groups were defined as having a <25 mm at <26 weeks (early group, 20 cases) and <31 (late 19 cases). The control group (75 ≥25 weeks. values 16–20, 21–25, 26–30 31–35 weeks, age‐related changes, treatments preterm labor, outcomes compared between groups. In 78...
Abstract Objectives: The aim of this study was to evaluate the beta‐adrenergic receptor (β‐AR) selectivity, organ specificity and efficacy delaying onset spontaneous delivery bedoradrine (KUR‐1246), a novel uterine relaxant. Methods: β‐AR selectivity evaluated in terms amount cyclic adenosine monophosphate produced by bedoradrine, ritodrine isoprenaline Chinese hamster ovary cells expressing human β 1 ‐, 2 ‐AR or 3 ‐AR. Inhibition contractions atrium, trachea proximal colon were compared...
Acute pulmonary thromboembolism (PTE) is a common illness that causes death and disability. Deep vein thrombosis (DVT) often found in patients with large myomatous uterus, can occasionally result acute PTE. Here, we describe the achievement of favorable outcome case PTE.The patient presented PTE caused by uterine leiomyoma, without DVT lower extremities. Percutaneous cardiopulmonary support (PCPS) was used as an adjunct to thrombolytic therapy treat right ventricular thrombus According...
BK-UM (CRM197) is a mutant form of diphtheria toxin and specific inhibitor heparin-binding epidermal growth factor-like factor (HB-EGF). We assessed the safety, pharmacokinetics, recommended dose, efficacy in patients with recurrent ovarian cancer (OC) or peritoneal (PC), measured HB-EGF levels serum abdominal fluid after administration. Eleven advanced OC PC were enrolled treated via intraperitoneal route. The dose was escalated (1.0, 2.0, 3.3, 5.0 mg/m2) using 3 + design. Eight 11...
We aimed to clarify the usefulness of procalcitonin (PCT) in evaluation histological chorioamnionitis (CAM) and prediction neonatal infantile outcomes as a reference interleukin-6 (IL-6).Subjects were 36 singleton pregnant women delivered at 22-37 weeks' gestation due threatened premature delivery and/or preterm rupture membranes. Cases classified into CAM non-CAM groups, according Blanc's criteria. Comparisons made on umbilical venous amniotic fluid PCT levels among groups. The relations...