A5101747015- Colorectal Cancer Surgical Treatments
- Neonatal Respiratory Health Research
- Gastric Cancer Management and Outcomes
- Advancements in Battery Materials
- Colorectal Cancer Treatments and Studies
- Supercapacitor Materials and Fabrication
- Advanced Battery Materials and Technologies
- Congenital Diaphragmatic Hernia Studies
- Radiomics and Machine Learning in Medical Imaging
- Advanced Photocatalysis Techniques
- Lung Cancer Diagnosis and Treatment
- Lung Cancer Treatments and Mutations
- Pelvic and Acetabular Injuries
- Hip and Femur Fractures
- Head and Neck Surgical Oncology
- Bone Tissue Engineering Materials
- Advances in Oncology and Radiotherapy
- Colorectal Cancer Screening and Detection
- Plasma Applications and Diagnostics
- Cardiac, Anesthesia and Surgical Outcomes
- Mental Health Research Topics
- Covalent Organic Framework Applications
- CO2 Reduction Techniques and Catalysts
- Colorectal and Anal Carcinomas
- Ammonia Synthesis and Nitrogen Reduction
Union Hospital
2025
Southern Medical University
2016-2025
Fujian Medical University
2025
Nanfang Hospital
2016-2025
Wenzhou Medical University
2020-2025
Second Affiliated Hospital & Yuying Children's Hospital of Wenzhou Medical University
2020-2025
First Affiliated Hospital of Wenzhou Medical University
2024-2025
Zhejiang Lab
2025
Zhengzhou University
2021-2024
Wuhan University of Technology
2023-2024
Abstract The precise identification of single‐atom catalysts (SACs) activity and boosting their efficiency toward CO 2 conversion is imperative yet quite challenging. Herein, for the first time a series porous organic polymers designed prepared simultaneously, containing well‐defined M–N 4 O sites. Such strategy not only offers multiactive sites to promote catalytic but also provides more direct chance identify metal center activity. photoreduction results indicate that introduction salphen...
Accurate prediction of peritoneal metastasis for gastric cancer (GC) with serosal invasion is crucial in clinic. The presence collagen the tumour microenvironment affects cells. Herein, we propose a signature, which composed multiple features serosa derived from multiphoton imaging, to describe extent alterations. We find that high signature significantly associated risk (P < 0.001). A competing-risk nomogram including size, differentiation status and lymph node constructed. demonstrates...
Abstract The current tumour-node-metastasis (TNM) staging system alone cannot provide adequate information for prognosis and adjuvant chemotherapy benefits in patients with gastric cancer (GC). Pathomics, which is based on the development of digital pathology, an emerging field that might improve clinical management. Herein, we propose a pathomics signature (PS GC ) derived from multiple features haematoxylin eosin-stained slides. We find PS independent predictor prognosis. A nomogram...
Electrocatalytic nitrate reduction reaction (NO
Epidermal growth factor receptor tyrosine kinase inhibitor (EGFR-TKI) resistance is a major obstacle in the treatment of non-small cell lung cancer (NSCLC). Epigenetic alterations have been shown to be involved NSCLC oncogenesis; however, their function EGFR-TKI remains uncharacterized. Here, we found that an EHMT2 inhibitor, UNC0638, can significantly inhibit and induce apoptosis EGFR-TKI-resistant cells. Additionally, also expression enzymatic activity levels were elevated Moreover,...
Abstract 3D porous organic frameworks, which possess the advantages of high surface area and abundant exposed active sites, are considered ideal platforms to accommodate single atoms (SAs) metal nanoclusters (NCs) in high‐performance catalysts; however, very little research has been conducted this field. In present work, a framework containing Ni 1 SAs n NCs is prepared through metal‐assisted one‐pot polycondensation tetraaldehyde hexaaminotriptycene. The sites clusters confined space...
Abstract Background This study aimed to develop and validate a model based on the collagen signature systemic immune-inflammation index predict prognosis in rectal cancer patients who underwent neoadjuvant treatment. Methods Patients with had residual disease after treatment at two Chinese institutions between 2010 2018 were selected, one used as training cohort other validation cohort. In total, 142 fully quantitative features extracted using multiphoton imaging, was generated by least...
The transformation of lung adenocarcinoma to small cell cancer (SCLC) is a recognized resistance mechanism and hindrance therapies using epidermal growth factor receptor tyrosine kinase inhibitors (TKIs). paucity pretranslational/posttranslational clinical samples limits the deeper understanding mechanisms exploration effective therapeutic strategies. Here, we developed preclinical neuroendocrine (NE) models. Next, identified transcriptional reprogramming that drives erlotinib in NE lines...
Thermogalvanic cells (TGCs) draw great attention in the field of heat to electricity conversion, but TGCs were only form liquid or organic gel. Here, we report an all-inorganic hydrogel TGC via simply mixing and stirring two inorganic salt solutions. Benefiting from hydrogen bonds resultant framework endogenous Fe
Abnormal pulmonary vascular development is a critical factor in the pathogenesis of bronchopulmonary dysplasia (BPD). Despite well-established sex-specific differences incidence BPD, molecular mechanism(s) behind these are not completely understood. Exposure to high concentration oxygen (hyperoxia) contributes BPD and creates profibrotic environment lung. Our objective was elucidate neonatal human microvascular endothelial cells (HPMECs) normoxic hyperoxic conditions, including propensity...
Premature male neonates are at a greater risk of developing bronchopulmonary dysplasia (BPD). The reasons underlying sexually dimorphic outcomes in premature not known. role miRNAs mediating sex biases BPD is understudied. Analysis the pulmonary transcriptome revealed that large percentage angiogenesis-related differentially expressed genes miR-30a targets. We tested hypothesis there differential expression vivo and vitro neonatal human microvascular endothelial cells (HPMECs) upon exposure...
Pneumonia is one of the common complications hip fracture. This study aimed to evaluate risk factors and apply a nomogram predict postoperative pneumonia in elderly fracture patients.From August 2014 October 2019, 1113 patients who were older than 65 years underwent surgical treatment our hospital subjects this study. Univariate multivariate Cox analyses used identify independent factors. A predictive model was built, discrimination calibration determined by receiver operating characteristic...
Abstract Huang Qin decoction (HQD) is a traditional Chinese medicine formula for treating colitis, but the effects and molecular mechanism of action HQD in colitis-associated carcinogenesis (CAC) are still unclear. Therefore, we aimed to determine beneficial on CAC mice reveal underlying involved. AOM/DSS was used induce mice, tumorigenesis were examined (with mesalazine serving as positive control). Mesalazine or treatment alleviated body weight loss decreased disease activity index induced...
This study investigated the role of L-3-n-Butylphthalide (NBP) in cardiac protection.The left anterior descending coronary arteries (LAD) rats were occluded for 30 min following by 2-h reperfusion to make ischaemia/reperfusion models. Neonatal cardiomyocytes cultured and subjected hypoxia. was administered intraperitoneally 2 h before surgery right after vivo experiments or added culture medium vitro. Haemodynamic parameters recorded evaluate functions, triphenyltetrazolium chloride (TTC)...
Abstract Potassium‐ion batteries (PIBs) have attracted tremendous attentions for scalable electrical energy storage owing to the abundant K resources. Heteroatom co‐doped hard carbon is considered be a reliable material boost ion transport and provide active sites reversible potassium storage. Herein, N/P dual‐doped 3D graphene aerogels (NPGAs) with hierarchical pores, enlarged interlayer distance, high doping level are successfully synthesized, which exhibit outstanding electrochemical...
BackgroundPrevious antibiotic exposure is an important risk factor for invasive fungal infection (IFI). Antibiotic overexposure common in lower-income countries; however, multi-centre studies concerning IFI relation to are scarce.AimThis prospective, matched case–control study explored the correlation of and very preterm infants or very-low-birthweight admitted 23 tertiary hospitals China between 2018 2021.MethodsUsing a 1:2 design gestational age, birth weight early-onset sepsis (yes/no),...