A5100325352- Pancreatic and Hepatic Oncology Research
- Gastrointestinal Tumor Research and Treatment
- Liver Disease Diagnosis and Treatment
- Acute Myocardial Infarction Research
- Cardiac Imaging and Diagnostics
- Gallbladder and Bile Duct Disorders
- Rheumatoid Arthritis Research and Therapies
- Neuroendocrine Tumor Research Advances
- Wound Healing and Treatments
- Cardiac Structural Anomalies and Repair
- Heterotopic Ossification and Related Conditions
- Lymphoma Diagnosis and Treatment
- Renal cell carcinoma treatment
- Space Satellite Systems and Control
- Infective Endocarditis Diagnosis and Management
- Bone fractures and treatments
- Antiplatelet Therapy and Cardiovascular Diseases
- Nanoplatforms for cancer theranostics
- Graphene and Nanomaterials Applications
- Gastrointestinal disorders and treatments
- Takotsubo Cardiomyopathy and Associated Phenomena
- Fatty Acid Research and Health
- Cardiac tumors and thrombi
- Ocular and Laser Science Research
- HER2/EGFR in Cancer Research
Chenzhou First People's Hospital
2024
Third Affiliated Hospital of Zhengzhou University
2024
Zhengzhou University
2024
Beijing Friendship Hospital
2022
Capital Medical University
2022
Beijing Obstetrics and Gynecology Hospital
2022
Mianyang Third People's Hospital
2022
Nanchang University
2020
Zhongshan Hospital of Xiamen University
2018
Air Force Medical University
2017
Background: Doxorubicin (Dox) can induce endotheliotoxicity and damage the vascular endothelium (VE). The most principle mechanism might be excess reactive oxygen species (ROS) generation. Nevertheless, characteristics of ROS generation, downstream mechanisms, target organelles in Dox-induced have yet to elucidated. Methods Results: In order explore related problems, VE injury models were established mice human umbilical vein endothelial cells (HUVECs) by endotheliotoxicity. Results showed...
Bone morphogenetic proteins (BMPs) delivered on scaffolds can induce ectopic bone formation after subcutaneous injection. Adenoviral vectors (Ad) carrying BMP2, BMP7, and BMP9 cDNAs have been shown to produce through endochondral ossification. The present study was performed elucidate the histological events leading ossification for two novel first-generation adenoviral constructs encoding BMPs, AdBMP4 AdBMP6. In vitro, viral produced secreted mature BMP4 BMP6 proteins. vivo, calf muscles of...
Abstract Background There are few reports of robot‐assisted pancreatic surgery. Our purpose was to report our surgical and clinical experiences outcomes 47 cases resection show that minimally invasive surgery is both feasible effective. Methods The medical records patients who underwent resections for adenocarcinoma, cystic tumours or other diseases at institution by a single team from March 2010 December 2011 were retrospectively analysed. Results 32 females 15 males with mean age 48.7 ±...
The optimally efficient production of thrombin by the prothrombinase complex relies on suitable positioning its component factors and substrate phosphatidylserine-containing lipid membranes. presence oxidatively damaged phospholipids in a membrane disrupts normal architecture bilayer might therefore be expected to interfere with activity. To investigate this possibility, we prepared vesicles containing oxidized arachidonoyl lipids, examined their ability accelerate prothrombinase. Oxidized...
Chronic HCV Patients taking PEG-IFN-α/R from different ethnic groups have probabilities of reaching a sustained viral response (SVR). There are many influence factors, such as genotype, IL-28B single-nucleotide polymorphisms (SNP), Fibrosis 4 index (FIB-4), and aspartate aminotransferase-to-platelet ratio (APRI) score. But the baseline factors in relation to treatment outcome was still not much clear. We evaluated data 231 chronic patients with or without liver fibrosis their antiviral...
Abstract CYP2C19 gene has multiple single nucleotide polymorphism (SNP), which is the major determinant for clopidogrel treatment responses. Therefore, SNP detection essential predicting efficacy. Currently, there still no quick and effective method routine of common SNPs in clinical laboratories, critically needed prior to treatment. AllGlo™ based quantitative PCR was used develop a novel genotyping detection, termed CyPAllGlo. The performance CyPAllGlo compared with that commonly...
With over 9 million fatalities per year expected by 2030, infectious diseases will remain a significant burden on the world economy and cause high mortality rates. An excellent method to increase bioactivity of levofloxacin (LEV) in pediatric abdominal wound repair is finding stimuli-based drug delivery system (DDS). We designed developed an LEV incorporated with zeolite imidazole framework-8 (ZIF-8) as promising nanocarrier for healing applications. The spectral analysis morphological...
Abstract Background: While benign duodenal tumours are rare compared with malignant tumours, they comprise a wide variety of pathologies. Despite their diagnostic challenge, the optimal management remains undefined. We aimed to review diagnosis and surgical treatment tumours. Methods: Records all patients post‐operative pathological tumour were retrieved. Information on clinical presentations, methods, locations, approaches, results patient outcomes analysed. Results: The operative spectrum...
Background To verify and evaluate the performance characteristics of a creatine kinase phosphokinase isoenzymes MB ( CK ‐ ) assay kit, which produced by Xiamen Innodx Biotech Co. Ltd. Methods Evaluation was carried out according to “Guidelines for principle analysis evaluation in vitro diagnostic reagent.” The parameters included detection limit, linearity range, reportable recovery test, precision verification, interference cross‐reactivity, matrix effect, method comparison. Results limit...
The short-term and long-term effects of coronary collateral circulation (CCC) discovered after acute myocardial infarction (AMI) are still debatable. This retrospective cohort study aimed to explore the clinical significance CCC for AMI patients.A consecutive series 323 patients with 1339 subjects without were enrolled, most them received percutaneous intervention AMI. Comparisons between non-CCC population sub-groups applied regarded basic characteristics, stenosis extent indicated by...
Introduction：The predictive value of soluble suppression tumorigenicity 2 (sST2) for the occurrence major adverse cardiovascular events (MACEs) in patients with ST‑segment elevation myocardial infarction (STEMI) remains unclear.We aimed to investigate role sST2 predicting MACEs STEMI after primary percutaneous coronary intervention (pPCI).A total 350 were enrolled this study. The levels sST2, N‑terminal pro-B‑type natriuretic peptide (NT‑proBNP), cardiac troponin I (TnI), and creatine...
In the research of space debris impact induced discharge measurements density and temperature plasma are very important difficult. Spectrum analysis is best method measuring hypervelocity plasma. This has been successfully used for detecting produced by particles with diameters larger than 1 mm. this paper, we present a light flash that 200 μm which foundation spectrum method. The characteristics also discussed.