A5105405234- Sirtuins and Resveratrol in Medicine
- Healthcare cost, quality, practices
- Antibiotic Use and Resistance
- Biochemical effects in animals
- Infection Control in Healthcare
- Autophagy in Disease and Therapy
- Infection Control and Ventilation
- Adipose Tissue and Metabolism
- Nosocomial Infections in ICU
- Healthcare Education and Workforce Issues
- Education and Learning Interventions
- Psychological and Temporal Perspectives Research
- Genetics, Aging, and Longevity in Model Organisms
- Healthcare Policy and Management
- Dietary Effects on Health
- Medical Device Sterilization and Disinfection
- Mobile Health and mHealth Applications
- Simulation-Based Education in Healthcare
- GDF15 and Related Biomarkers
- Amyotrophic Lateral Sclerosis Research
- Hydrogen's biological and therapeutic effects
- Chemical Safety and Risk Management
- Food Safety and Hygiene
- DNA Repair Mechanisms
- Occupational Health and Safety Research
Policlinico Tor Vergata
2024
University of Rome Tor Vergata
2023-2024
Massachusetts Institute of Technology
2009-2012
Chronic obstructive pulmonary disease/emphysema (COPD/emphysema) is characterized by chronic inflammation and premature lung aging. Anti-aging sirtuin 1 (SIRT1), a NAD+-dependent protein/histone deacetylase, reduced in lungs of patients with COPD. However, the molecular signals underlying aging lungs, whether SIRT1 protects against cellular senescence various pathophysiological alterations emphysema, remain unknown. Here, we showed increased COPD patients. activation both genetic...
Mammalian sirtuins have diverse roles in aging, metabolism and disease. Recently we reported a new function for SIRT5 urea cycle regulation. Our study uncovered that localized to mitochondria matrix deacetylates carbamoyl phosphate synthetase 1 (CPS1), an enzyme which is the first rate-limiting step of cycle. Deacetylation CPS1 by resulted activation enzymatic activity. Indeed, SIRT5-deficient mice failed up-regulate activity showed hyper ammonemia during fasting. Similar effects are also...
ABSTRACT Aim To assess nursing staff' knowledge and self‐efficacy in vascular access device management before after a Field Training Course, aligned to the recent Standard of Infusion Therapy Guidelines. Design Quasi‐experimental study. Method Nursing staff from healthcare company Rome, Italy, participated 25‐h focusing on management, promoting collaborative learning, reflection research. Participants filled Nurses' devices questionnaire pre post‐course. The course's impact was assessed...
Introduction Healthcare-associated infections (HAIs) and antimicrobial resistance (AMR) are major public health threats in upper- lower-middle-income countries. Electronic records (EHRs) an invaluable source of data for achieving different goals, including the early detection HAIs AMR clusters within healthcare settings; evaluation attributable incidence, mortality, disability-adjusted life years (DALYs); implementation governance policies. In Italy, burden is estimated to be 702.53 DALYs...
Hospital-acquired infections (HAIs) present a global public health challenge, impacting patient safety and incurring substantial economic costs across healthcare settings. This study aims to accurately measure the financial burden of HAIs by analyzing real associated with various infections, providing insights for targeted prevention management strategies.
This study investigates the impact of invasive procedures on healthcare-associated infections (HAI) at Policlinico Universitario Tor Vergata in Rome, Italy, aiming to understand their role device-associated HAI and inform prevention strategies.
<sec> <title>BACKGROUND</title> Care-Related Infections, are infectious diseases that occur in a care setting. The most important methods of prevention hand hygiene and proper use gloves gowns. Recent literature points out mobile devices being contact with hands or potentially contaminated environments can promote an increased occurrence HAIs. </sec> <title>OBJECTIVE</title> purpose our study is, therefore, to analyze the correlation between microbial population present on handprints health...
Background. The internship represents an experience that incorporates numerous meanings and values involve nursing students globally, particularly for those belonging to Generation Z. Aims. 1) assess the students' perceptions of clinical learning environments, 2) identify elements contribute determining environment, 3) compare quantitative qualitative results highlight key can support development targeted educational strategies students. Design. Convergent parallel mixed-method study...
Abstract Backgrounds Healthcare-associated infections (HAIs) increase morbidity, mortality, and costs, necessitating effective prevention strategies. This study estimates the additional costs of HAIs in a university hospital Rome, Italy Policlinico Tor Vergata (PTV), to inform policymakers, healthcare professionals, researchers. Methods We conducted retrospective cohort study, including all patients admitted or discharged 2018. applied propensity score matching (PSM) balance groups then we...