A5050937637- Cutaneous lymphoproliferative disorders research
- Chemotherapy-related skin toxicity
- Lymphoma Diagnosis and Treatment
- Nail Diseases and Treatments
- Autoimmune Bullous Skin Diseases
- Eosinophilic Disorders and Syndromes
- Nonmelanoma Skin Cancer Studies
- Urticaria and Related Conditions
- Cancer and Skin Lesions
- Cutaneous Melanoma Detection and Management
- Ear and Head Tumors
- Research on Leishmaniasis Studies
- Drug-Induced Adverse Reactions
- Lung Cancer Treatments and Mutations
- Intramuscular injections and effects
- Chronic Lymphocytic Leukemia Research
- Shoulder Injury and Treatment
- Vascular Tumors and Angiosarcomas
- Orthopedic Infections and Treatments
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Soft tissue tumors and treatment
- Genetic and rare skin diseases.
- Orthopedic Surgery and Rehabilitation
- Hematological disorders and diagnostics
- Soft tissue tumor case studies
Hospital Universitario Infanta Cristina
2015-2024
Centre for Genomic Regulation
2024
Hospital de Santa Maria
2020-2023
Centro Hospitalar Lisboa Norte
2020-2022
Fundación Instituto Valenciano de Oncología
2015
Hospital Universitario de Fuenlabrada
2010-2013
Hospital Universitario Puerta de Hierro Majadahonda
2006-2008
Instituto Nacional de la Salud
1992
Centro Nacional de Microbiologia
1987-1992
Little is yet known about the origin and protective mechanism of free nucleic acids in plasma. We investigated possibility these being particle associated. Plasma samples from colon cancer patients cell culture media were subjected to various antibody incubations, ultracentrifugation, RNA extraction protocols for total RNA, epithelial mRNA. Flow cytometry using a Ber-EP4 confocal laser microscopy after staining with propidium iodide also performed. mRNA levels LISCH7 SDHA genes determined...
The secreted mitogen vascular endothelial growth factor, VEGF, plays a pivotal role in angiogenesis. Hypoxia, inactivation of p53 and oncogenic K-Ras induce VEGF expression. Other factors such as p73 may also affect levels. Curiously, regulate angiogenesis by affecting the expression pigment epithelium-derived PEDF. Additionally, might harbor additional functions through activation E2F transcription factors. Recently, new variant formed alternative splicing, VEGF(165)b, has been described...
Leishmaniasis, an endemic infection in Spain, is caused by protozoan parasites of the Leishmania genus. Between 2010 and 2012, there was outbreak cutaneous visceral leishmaniasis Fuenlabrada, Madrid.To describe cases diagnosed over a 17-month period at dermatology department Hospital de Fuenlabrada.We analyzed epidemiological, clinical, histological, microbiological features each case also evaluated treatments administered outcomes.We studied 149 cases. The incidence showed peak age range...
Primary cutaneous B-cell lymphomas (PCBCLs) are that can occur in the skin without evidence of extracutaneous involvement. The 2005 WHO/EORTC classification and its 2018 update have distinguished three main categories based on clinicopathological, immunohistochemical, genetic characteristics: primary marginal zone lymphoma (PCMZL), follicle centre (PCFCL), diffuse large lymphoma, leg type (PCDLBCL-LT). PCMZL PCFCL clinically indolent, while PCDLBCL-LT is an aggressive lymphoma. Due to low...
Primary cutaneous lymphomas are uncommon. This article describes the Cutaneous Lymphoma Registry of Spanish Academy Dermatology and Venereology (AEDV) reports on results from first year. Disease registry for patients with primary lymphoma. The participating hospitals prospectively recorded data diagnosis, treatment, tests, disease stage all A descriptive analysis was performed. In December 2017, contained 639 (60% male) 16 university hospitals. most common diagnoses, in order frequency, were...
Depilation techniques have gain popularity in the last few decades. Nowadays there are available a wide variety of lasers as well intense pulsed light for depilation. However, little is known about long-term effects these procedures when melanocytic nevi affected by them. We report cases three patients where we observed clinical, dermoscopic and histopathological changes secondary to laser therapy depilation, respectively. believe that it necessary perform further studies prove absence...
Human leishmaniasis produced by Leishmania infantum is endemic in Mediterranean countries. In the context of a outbreak town Fuenlabrada, Madrid, Spain, we had two patients with cutaneous that developed non-necrotizing granulomas. They both been receiving anti-TNF treatment adalimumab for rheumatic diseases. Neither them visceral disease and did not require withdrawal to control disease. It well known therapy associated opportunistic diseases, especially those which granuloma formation an...
Primary cutaneous B-cell lymphomas (PCBCLs) are that can occur in the skin without evidence of extracutaneous involvement. The 2005 WHO/EORTC classification and its 2018 update have distinguished three main categories based on clinicopathological, immunohistochemical genetic characteristics: primary marginal zone lymphoma (PCMZL), follicle centre (PCFCL), diffuse large lymphoma, leg type (PCDLBCL-LT). PCMZL PCFCL clinically indolent, while PCDLBCL-LT is an aggressive lymphoma. Due to low...
Abstract Background Reliable prognostic factors for patients with primary cutaneous anaplastic large cell lymphoma ( PCALCL ) are lacking. Objective To identify specific survival in . Methods Using the convenience sampling method, diagnosed from May 1986 to August 2017 16 University Departments were retrospectively reviewed. Results One hundred eight included (57 males). Median age at diagnosis was 58 years. All of them showed T1‐3N0M0 stages. Seventy per cent cases presented a solitary...