A5068069856- Optical Network Technologies
- Appendicitis Diagnosis and Management
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- X-ray Diffraction in Crystallography
- Photonic Crystal and Fiber Optics
- Diverticular Disease and Complications
- Trauma and Emergency Care Studies
- Advanced Fiber Optic Sensors
- Acute Ischemic Stroke Management
- Crystallization and Solubility Studies
- Cardiac, Anesthesia and Surgical Outcomes
- Intraperitoneal and Appendiceal Malignancies
- Banking stability, regulation, efficiency
- Stroke Rehabilitation and Recovery
- Streptococcal Infections and Treatments
- Vascular Procedures and Complications
- Traumatic Brain Injury and Neurovascular Disturbances
- Antimicrobial Resistance in Staphylococcus
- Advanced Photonic Communication Systems
- Semiconductor Lasers and Optical Devices
- Orthopedic Infections and Treatments
- Central Venous Catheters and Hemodialysis
- Intestinal and Peritoneal Adhesions
- finance, banking, and market dynamics
- Bacterial Identification and Susceptibility Testing
University of Cincinnati Medical Center
2022-2024
University of Cincinnati
2022-2023
United States Air Force
2023
Saint Louis University
2016-2022
Cancer Institute of New South Wales
2022
VA Eastern Colorado Health Care System
2022
Washington University in St. Louis
2017-2020
Barnes-Jewish Hospital
2018
Lufthansa (Germany)
2018
Christ University
2013-2016
The synthesis, structural, and electronic properties of nine 1,3-diphenyl-6-alkyl/aryl substituted pentafulvenes were studied. Pyrene ring π-π interactions revealed from analysis the experimental crystal packing 1,3-diphenyl-6-(1-pyrene)fulvene supporting DFT calculations. Photophysical derived UV-vis fluorescence emission measurements demonstrated tunable low HOMO-LUMO band gaps for series. presented results point to a model synthetic approach incorporation extended π systems...
The hemostatic properties of tranexamic acid (TXA) are well described, but the immunological effects TXA administration after traumatic injury have not been thoroughly examined. We hypothesized would reduce monocyte activation in bleeding trauma patients with severe injury.This was a single center, double-blinded, randomized controlled trial (RCT) comparing placebo to 2 g or 4 intravenous bolus dose injury. Fifty were into each study group. primary outcome reduction as measured by human...
In recent years, numerous security, military, and medical applications have been developed which use Terahertz (THz) radiation. These developments heightened concerns in regards to the potential health risks that are associated with this type of To determine cellular molecular effects caused by THz radiation, we exposed several human cell lines high-power then determined death thresholds gene expression profiles. Necrotic apoptotic were for Jurkat cells using an optically-pumped gas source...
A three-wavelength Raman fiber laser is presented that suitable for the generation of a flattened gain curve over broad range extended telecommunications bandwidths. This utilizes an 1100-nm Yb-doped cladding pumped and cascaded resonator to generate output radiation at 1427, 1454, 1480 nm. The slope efficiency conversion from 1100- 14xx-nm 0.38, total power 1.1 W, "wall-plug" 0.10. 1454 nm adjusted by varying reflectivity grating couplers suppression lower order spectral components between...
With the publication of recent trials showing tremendous benefits mechanical thrombectomy, opportunities exist to refine prehospital processes identify patients with larger stroke syndromes.We retrospectively reviewed consecutive who were brought via scene flight from rural parts region our institution, December 1, 2014 June 5, 2015, severe hemiparesis or hemiplegia. We assessed accuracy diagnosis and number requiring endovascular therapy. Moreover, we times along pathway treated therapy.45...
Previous studies have suggested that percutaneous drainage and interval appendectomy is an effective treatment for appendicitis with associated abscess. Few to date analyzed risk factors failed drain management. We hypothesized older patients more co-morbidities would be at higher failing conservative treatment.The 2010-2014 editions of the National Inpatient Sample (NIS) were queried diagnoses peri-appendiceal abscesses. Minors elective admissions excluded. identified who underwent defined...
A novel six-wavelength Raman fibre laser exhibiting a dynamic gain flattening capability in the C+L optical telecommunications band is demonstrated. The power distribution six lasing wavelengths adjusted with voltage-controlled Bragg-grating output couplers. was used as pump source for distributed amplification several transmission span lengths. For example, multi-wavelength provides an on/off of 19 dB over 100 km True-Wave RS fibre. measured flatness 1.7 peak–peak and effective noise figure...
Necrotizing soft-tissue infections (NSTIs) result in significant morbidity and mortality rates, with as many 76% of patients dying during their index admission. Published data suggest NSTIs rarely involve fungal immunocompetent patients. However, because the recent recognition our population, we hypothesized that such frequently complicate are associated higher rates.A prospectively maintained Acute Critical Care Surgery (ACCS) database spanning 2008-2015 including more than 7,000 was...
With the advent of anti-Helicobacter pylori therapy, hospital admissions for peptic ulcer disease (PUD) have declined significantly since 1990s. Despite this, operative treatment PUD still is common. Although previous papers suggest that Candida in peritoneal fluid cultures may be associated with worse outcomes patients perforated ulcers (PPUs), post-operative anti-fungal therapy has not been effective. We hypothesized pre-operative drugs improve PPUs undergoing management.A prospectively...
Objectives and importance of study: Colorectal cancer (CRC) is Australia's fourth most commonly diagnosed cancer. CRC screening an effective intervention to reduce this burden. The National Bowel Cancer Screening Program (NBCSP) provides 2-yearly immunochemical faecal occult blood tests (iFOBTs) Australians aged 50–74 years; a diagnostic colonoscopy conducted after positive iFOBT. Clinical guidelines inform usage, appropriate use these vital investigate gastrointestinal symptoms, detect...
We discuss amplified spontaneous emission (ASE) generated in Raman amplifiers that are counter-pumped with trains of pulses. Our experimental and theoretical results show if the peak power pump pulses is too high, ASE output from amplifier can be significantly higher than a continuous-wave pumped providing same gain. This effect places lower limit on duty cycle one use for given level Furthermore, we report an additional enhancement there insufficient walkoff between copropagating to average...
Broad-spectrum antibiotic therapy is critical in the management of necrotizing soft tissue infections (NSTI) emergency setting. Clindamycin often included empirically to cover monomicrobial gram-positive pathogens but probably little value for polymicrobial and associated with significant side effects, including induction Clostridium difficile colitis. However, there have been no studies predicting prior obtaining cultures. The purpose this study was identify independent predictors NSTI...
We demonstrate 1.6 Tb/s (40 /spl times/ 42.7 Gb/s) WDM transmission over 2000 km of fiber with 100-km amplifier spacing and 100-GHZ channel spacing. Error free all 40 C-band channels is achieved. employ dispersion-managed spans, hybrid Raman/Er-doped inline amplifiers. forward error correction to achieve this record Gb/s distance terrestrial span lengths.
:A highly efficient configurable three-wavelength cascaded Raman laser suitable for broadband amplification is demonstrated. The power at each wavelength adjusted by varying the reflectivity of fiber grating output couplers. Measurements stability show that source stable.
Critical infrastructure can be vulnerable to cyber attacks through 802.11 wireless networks. Because intruders are within short range of the targeted network, they directly observed by security forces cued their presence. WildCAT is a prototype system that extends reach physical force into realm detect and respond threats vulnerabilities. Its design uses vehicles as platform for collecting network activity then sent via cellular an analysis center. At center, specialists suspicious cue its...
Antibiotic-impregnated central venous catheters (CVCs) decrease the incidence of infection in high-risk patients. However, use these carries hypothetical risk inducing antibiotic resistance. We hypothesized that routine minocycline and rifampin-impregnated (MR-CVC) a single intensive care unit (ICU) would change resistance profile for Staphylococcus aureus.We reviewed susceptibilities S. aureus isolates obtained from blood cultures large urban teaching hospital 2002-2015. Resistance patterns...
Osteomyelitis is a progressively destructive invasive infection of the bone that can result in both localized and systemic illness. This includes an acute suppurative infection, generalized weakness, failure to thrive, pathological fracture, non-healing ulcers. When chronic osteomyelitis develops, therapeutic options are limited, as antimicrobial agents cannot penetrate necrotic bone, repeated surgical debridement may be needed. Re-establishing full thickness coverage wounds ulcers...
Background: The link between Helicobacter pylori infection and peptic ulceration is well established. Recent studies have reported a decrease of H. pylori-related ulcer disease; eradication likely the cause this decrease. We hypothesized that patients with pylori-positive perforated disease (PPUD) requiring surgical intervention had worse outcomes than pylori-negative PPUD. Patients Methods: A prospectively collected Acute Critical Care Surgery registry spanning years 2008 to 2015 was...
Gun violence killed over 46,000 Americans in 2021; almost 120,000 suffered gunshot wounds. This epidemic has attracted national attention and increasing concern from medical surgical organizations, as evident this special issue. 'Through Through History' explores the management of wounds their earliest appearance 14th-century Europe to present. Interweaving civilian military experience, it details not only evolution care directly applied patients but also social, political, scientific milieu...