Zhen Xie

ORCID: 0000-0003-0722-5168
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Research Areas
  • Dermatology and Skin Diseases
  • Psoriasis: Treatment and Pathogenesis
  • Contact Dermatitis and Allergies
  • Cardiovascular Function and Risk Factors
  • Cardiovascular Disease and Adiposity
  • Pesticide Exposure and Toxicity
  • Tryptophan and brain disorders
  • Cancer Immunotherapy and Biomarkers
  • Herpesvirus Infections and Treatments
  • Cancer Genomics and Diagnostics
  • Advanced biosensing and bioanalysis techniques
  • DNA and Biological Computing
  • Ferroptosis and cancer prognosis
  • Cell Image Analysis Techniques
  • Urticaria and Related Conditions
  • Molecular Communication and Nanonetworks
  • Acute Kidney Injury Research
  • Chronic Obstructive Pulmonary Disease (COPD) Research
  • Stress Responses and Cortisol
  • Gut microbiota and health
  • Asthma and respiratory diseases
  • Cardiovascular, Neuropeptides, and Oxidative Stress Research
  • Tannin, Tannase and Anticancer Activities
  • Hemodynamic Monitoring and Therapy
  • Nutrition, Health and Food Behavior

University of Electronic Science and Technology of China
2020-2024

Sun Yat-sen University
2022-2024

The First Affiliated Hospital, Sun Yat-sen University
2022-2024

Jilin University
2023-2024

First Affiliated Hospital of Chengdu Medical College
2022-2024

Xingtai People's Hospital
2023

Hebei Medical University
2023

Huazhong University of Science and Technology
2022

Northwest University
2022

Research Medical Center
2022

An otherwise healthy 23-year-old woman presented with facial symmetrical erythema and slight itching lasting 4 days. Symptoms developed after wearing a KN95 (FFP2 equivalent) mask for 2 days to prevent contracting SARS-CoV-2. One day before, the patient had consulted emergency department presumptive diagnosis of acute cutaneous lupus erythematosus by general doctors was made because her gender erythema. However, physical examination medical history family were unremarkable. Blood urine...

10.1111/cod.13599 article EN Contact Dermatitis 2020-05-11

Cancer-related fatigue (CRF) is the most common symptom in patients with advanced non-small cell lung cancer (NSCLC) undergoing treatment chemotherapy. However, evidence upon which to base management strategies scarce. Traditional Chinese Medicine (TCM) has been shown be beneficial CRF. herbal injections should administered under an evidence-based approach. This trial aims assess efficacy and safety of addition Shenmai injection (SMI) conventional therapy for CRF NSCLC The study a two-group,...

10.1186/s13063-018-2845-7 article EN cc-by Trials 2018-09-04

Objectives: Psoriasis is a common chronic recurrent dermatitis. Accumulating observations show gut microbiota dysbiosis in psoriasis. We intend to further investigate the relationship between intestinal and psoriasis development. Design: first performed an epidemiological investigation on differences of gastrointestinal discomfort symptoms patients with general population. Then variation (un)treated acitretin plus narrow-band ultraviolet B (NB-UVB) was analyzed by 16S rRNA sequencing. last...

10.3389/fnut.2021.761978 article EN cc-by Frontiers in Nutrition 2021-11-22

Abstract Background Chronic kidney disease (CKD) is a common comorbidity of chronic obstructive pulmonary (COPD). Although high hemoglobin (Hb) detrimental to CKD patients, its relationship with poor outcomes in the COPD population has not been reported. This study aimed investigate between Hb and in-hospital mortality explore reference intervals patients CKD. Methods retrospective was multicenter population-based. A total 47,209 who presented January 2012 December 2016 were included. The...

10.1186/s12890-019-0933-4 article EN cc-by BMC Pulmonary Medicine 2019-09-18

// Yuanhan Chen 1 , Zhen Xie 2 Chenggen Xiao 1, 3 Min Zhang 4 Zhilian Li Jianteng Yusheng 5 Xingchen Zhao 6 Pengfei Zeng Liyi Mo 7 Xinling Liang Wei Shi Division of Nephrology, Guangdong General Hospital, Academy Medical Sciences, Guangzhou, China Department Dermatology, Sichuan Sciences & Provincial People's Chengdu, Xiangya Central South University, Hunan, Gastroenterology, The Sixth Affiliated Sun Yat-Sen Second Internal Medicine, Wuhua Guangdong, Southern Dongguan Province,...

10.18632/oncotarget.15705 article EN Oncotarget 2017-02-25

There is an obvious need for more prompt and specific biomarkers of bacterial infections in generalized pustular psoriasis patients. The aim this study was to evaluate the diagnostic properties define appropriate cut-off values procalcitonin C-reactive protein predicting infection Sixty-four patients hospitalized from June 2014 May 2017 were included retrospective study. procalcitonin, protein, details infection, other clinical parameters analyzed. Receiver operating characteristic curve...

10.1016/j.abd.2019.09.022 article EN cc-by Anais Brasileiros de Dermatologia 2019-09-01

Abstract Background The Charlson Comorbidity Index (CCI) can be automatically calculated from the International Classification of Disease (ICD) code. However, feasibility this transformation has not been acknowledged, particularly in hospitals without a qualified ICD coding system. Here, we investigated utility coding-based CCI China. Methods A multi-center, population-based, retrospective observational study was conducted, using dataset incorporating 2,464,395 adult subjects 15 hospitals....

10.1186/s12913-020-05273-8 article EN cc-by BMC Health Services Research 2020-05-18

The aim of this study was to explore the relationship between two genetic variants (rs2275913 and rs3748067) interleukin-17A (IL-17A) risk ovarian endometriosis in northern Chinese women. This performed 316 patients with 328 female control subjects. genotypes polymorphisms were determined by polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) method. mRNA expression IL-17A detected quantitative real-time PCR (qRT-PCR). There a significant difference genotype...

10.1080/01443615.2023.2199852 article EN cc-by Journal of Obstetrics and Gynaecology 2023-04-17

Background There are significant differences in the prevalence and prognosis of atrial fibrillation (AF) between sexes. Epicardial adipose tissue (EAT) has been found as a risk factor for AF. This study aimed to evaluate whether sex-based EAT were correlated with AF recurrence major adverse cardiovascular events (MACE). Methods In this study, postmenopausal women age, BMI, type matched men who had received first catheter ablation included. volume was quantified based on pre-ablation cardiac...

10.3389/fcvm.2022.905351 article EN cc-by Frontiers in Cardiovascular Medicine 2022-06-13

The tryptophan‐depleting enzyme indoleamine‐2,3‐dioxygenase (IDO) is critical for the regulation of immunotolerance and plays an important role in immune‐associated skin diseases. To analyse level IDO condyloma acuminata (CA) its this condition. expression was assessed peripheral blood healthy controls patients with CA. assess immunity, ability isolated epidermal cells to metabolize tryptophan influence on polyclonal T‐cell mitogen (PHA)‐stimulated proliferation were explored. median...

10.1111/bjd.15356 article EN British Journal of Dermatology 2017-01-29

Abstract Background: Nasopharyngeal carcinoma (NPC) is a tumor that commonly found in southern China. NPC has several risk factors, such as infection with the Epstein–Barr virus. However, we know little about factors for eye metastasis (EM) male patients NPC. Serum lipids are well recognized cardiovascular disease, and recent studies show they also have relationship development of Purpose: We designed present study to determine whether were relevant EM by detecting levels serum lipids....

10.1042/bsr20201082 article EN Bioscience Reports 2020-06-01

The authors declare no conflicts of interest.

10.1111/cod.13636 article EN Contact Dermatitis 2020-06-08

High expression of Stathmin 1 (STMN1) protein is related to a poor prognosis in various tumors, including breast cancer. In our previous study, phospho-STMN1 signature was conducted predict outcomes adjuvantly treated cancer patients. This study aimed explore the relationship STMN1 with and patients neoadjuvant chemotherapy (NACT).A retrospective analysis 116 who received NACT The First Affiliated Hospital Sun Yat-sen University between December 2008 March 2016 conducted. Patients were...

10.21037/gs-22-628 article EN Gland Surgery 2022-11-01

Luminal B breast cancer is routinely treated with chemotherapy and endocrine therapy. However, its sensitivity to treatment remains heterogeneous; therefore, identifying patients who may most benefit crucial. Immune-related genes are reportedly related the prognosis of cancer. The purpose this study was evaluate impact an immune-related gene signature (IRGS) in predicting We selected from two large datasets: 488 Metabric dataset (training cohort) 250 Cancer Genome Atlas (TCGA) (validation...

10.21037/gs-24-377 article EN Gland Surgery 2024-12-01

10.36468/pharmaceutical-sciences.1366 article EN Indian Journal of Pharmaceutical Sciences 2024-01-01

Background Rosacea has a high incidence, significantly impacts quality of life, and lacks sufficient diagnostic techniques. This study aimed to investigate the feasibility laser speckle contrast imaging (LSCI) for measuring facial blood perfusion in patients with rosacea identify differences flow among various regions associated different subtypes. Methods From June December 2023, 45 were recruited, 9 excluded, leaving 36 subjects: 12 erythematotelangiectatic (ETR), papulopustular (PPR),...

10.3389/fimmu.2024.1419005 article EN cc-by Frontiers in Immunology 2024-08-23

Dear Editor, A 21-year-old woman presented with a pruritic erythematous area and pustules on her right palm for 5 days (a). She was treated topical steroids without improvement. Her contact pet hedgehog suggested tinea incognito (b).1 This confirmed by cultures from the lesion pet's quill. Microscopic examination of two slide fluorescence staining revealed similar teardrop-shaped microconidia along sides hyphae. Scanning electron microscopy quill demonstrated dense biofilms hyphae (c)....

10.1111/bjd.19206 article EN British Journal of Dermatology 2020-06-15

The formation of the pre-metastatic niche (PMN), which precedes establishment tumor lesions, plays a critical role in cancer recurrence and metastasis. Hepatic stellate cells (HSCs), liver stromal cell component, can be induced to facilitate metastasis by modeling PMN formation. In present study, activated HSCs were observed peritumor non-cancerous tissues (PNLT) colorectal adenocarcinoma (CRALM), density was higher PNLT compared with that normal (NLT). High HSC positively associated number...

10.3892/ol.2020.12150 article EN Oncology Letters 2020-09-23
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