A5016453697- Dialysis and Renal Disease Management
- Renal Diseases and Glomerulopathies
- Chronic Kidney Disease and Diabetes
- Renal function and acid-base balance
- Nutrition and Health in Aging
- Venomous Animal Envenomation and Studies
- Vasculitis and related conditions
- Rabies epidemiology and control
- Body Composition Measurement Techniques
- Acute Kidney Injury Research
- Pregnancy and preeclampsia studies
- Systemic Lupus Erythematosus Research
- Central Venous Catheters and Hemodialysis
- Renal cell carcinoma treatment
- Hemodynamic Monitoring and Therapy
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Vascular Procedures and Complications
- Diet and metabolism studies
- Cytomegalovirus and herpesvirus research
- Renal and Vascular Pathologies
- Healthcare cost, quality, practices
- Health Systems, Economic Evaluations, Quality of Life
- Organ Donation and Transplantation
- Pregnancy and Medication Impact
- Vascular anomalies and interventions
Jawaharlal Institute of Post Graduate Medical Education and Research
2016-2025
Jawaharlal Nehru Medical College
2024
Creative Commons
2023
St.John's Medical College Hospital
2023
Sri Venkateshwaraa Medical College Hospital and Research Centre
2022
Pediatric Nephrology of Alabama
2021
Metabolic acidosis (MA) is associated with a loss of muscle mass and faster deterioration kidney function in patients chronic disease (CKD). A few single-centre randomized trials have reported favourable outcomes following correction MA. Additional good quality evidence on the safety efficacy alkali supplementation required epidemiologically different patient subsets CKD.A single-centre, open-label, randomized, prospective parallel-group study was conducted to assess effect MA body...
Health-related quality of life is an important, yet neglected aspect chronic kidney disease (CKD) care. We evaluated the and its determinants across CKD 3 to 5D using a specific tool (Kidney Disease Quality Life-SF™) in underprivileged, predominantly rural population with high rates illiteracy unemployment. The scores individual domains were summarized three composite - physical summary (PCS), mental (MCS), component score (KDCS). A total number 204 participants recruited from nephrology...
Abstract Introduction: This study presents a vascular access and renal transplantation (VART) program to address urology residents’ gaps in open techniques. It aims enhance Vascular Access Education (VAE), helping residents excel arteriovenous fistulas (AVF) providing model for advancements hemodialysis transplantation. Aims: To evaluate the outcomes of AVFs created by undergoing dedicated 4-month structured transplant program. Subjects Methods: We did retrospective analysis between May 2022...
Background Persistent metabolic acidosis (MA) in hemodialysis (HD) patients leads to protein breakdown, insulin resistance, and increased cardiovascular mortality. However, there is limited literature on the prevalence, determinants, impact of MA HD India. We studied association between intake lean body mass (LBM) with severity regular HD. Materials Methods This single-center, cross-sectional study which enrolled >18 years for at least 3 months. Normalized catabolic rate (nPCR) was...
Chronic kidney disease (CKD) is being increasingly recognized as a public health problem in India. The entity of CKD undetermined etiology (CKDu) reported globally. Here we describe the burden CKDu heretofore undescribed population South India.We prospectively enrolled all patients with referred to nephrology department an observational registry. We analyzed their sociodemographic and clinical features over 4 years. diagnosis its was determined using predefined criteria. Geolocalization...
There is only limited information on the epidemiology and outcomes of acute kidney injury (AKI) in critically ill patients from low- middle-income countries. This study aims to identify etiology, short-term outcomes, determinants mortality with AKI admitted multiple medical surgical Intensive Care Units (ICU's) a tertiary care center. The also compare clinical characteristics community-acquired (CAAKI) hospital-acquired (HAAKI). A prospective, observational was done June 2013 October 2015....
Snakebite is a common occupational hazard in tropical countries. To date, the literature on snakebite-related acute kidney injury (AKI) has been limited by retrospective study designs, lack of uniformity case definitions AKI and follow-up. This aims to identify in-hospital outcomes long-term changes function that follow haemotoxic envenomation.All adult patients admitted with following envenomation from January 2016 June 2017 were recruited followed up until July 2018. Predictors mortality...
Background: There is only limited information on the utility of urinary biomarkers in predicting long-term kidney function following acute injury (AKI). The current study assessed whether beta 2 microglobulin/creatinine (B2M/creat) and molecule-1/creatinine (KIM-1/creat) ratios, measured early recovery phase AKI, are predictive at one year. Methods: This a prospective done tertiary care centre South India, from March 2017 to December 2018. Adult patients who survived an episode AKI were...
Abstract Background Superficial and deep fungal infections are more frequent in transplant recipients primarily because of the failure cell‐mediated immunity lesser amount antigen‐presenting Langerhans cells their epidermis. Here, we report seven cases post‐renal subcutaneous phaeohyphomycosis, all which manifested within 1 year after transplantation were unresponsive to prolonged courses itraconazole. This is first case series, our knowledge, phaeohyphomycosis India. Method We performed a...
There is limited data on the etiology, clinical and histopathological spectrum outcomes of crescentic glomerulonephritis (CrGN) in adult Indian population. This prospective study was done to evaluate clinicohistological patterns predictors outcome CrGN South All patients received standard protocol based immunosuppression addition supportive care. Immune-complex (ICGN) most common etiology (n = 31; 77.5%) followed by pauci-immune (PauciGN; n 8; 20%) anti-glomerular basement membrane disease...
Membranous nephropathy (MN) is the most common cause of nephrotic syndrome in adults. About 80% MN cases are primary, whereas rest result from multiple secondary causes.1Trujillo H. Alonso M. Praga New ways understanding membranous nephropathy.Nephron. 2020; 144: 261-271Crossref PubMed Scopus (11) Google Scholar In early days modern medicine, mercurial organic compounds were used as diuretics, laxatives, and anti-infective agents. The use mercury a pharmacologic agent was abandoned by...
Ifosfamide (IFO), an alkylating agent used for the management of solid organ tumors, can cause reversible Fanconi's syndrome and acute kidney injury. Karyomegalic interstitial nephropathy (KIN) is a rare form chronic tubulointerstitial nephritis, initially described as familial in adults. So far, four cases KIN have been reported pediatric adolescent population following treatment with IFO. We report 22-year-old man who developed renal dysfunction IFO therapy relapsed Hodgkin's lymphoma....
Bioimpedance analyzers uses these differences in the electrical properties of human body to analyze cellular and water components. Human acts as a semiconductor, with various compartments offering resistance (R) reactance (X) passage alternating current. The X R thus measured can be used validated regression equations or mathematical models provide information on water, fat, fat-free mass. Depending number frequencies used, available equipments include single frequency, multifrequency...
There is limited literature on the prevalence and determinants of sarcopenia in Indian predialysis chronic kidney disease (CKD) population. The current study attempts to characterize CKD stages 3 & 4 using 3-compartment model dual-energy X-ray absorptiometry (DXA).This secondary data from a randomized trial bicarbonate supplementation for preserving muscle mass. A DXA was done assess body composition 188 subjects aged 18 65, with stable function. Sarcopenia defined by Asian Working Group...
The incidence of acute kidney injury (AKI) has increased in the recent past. Patients with AKI have an risk mortality. They are also at developing chronic disease (CKD). can lead to irreversible loss renal function despite complete clinical recovery. Currently, no tools available diagnose this subclinical function. Renal functional reserve (RFR) serve as essential tool for analyzing function, and patients RFR post-AKI may be closely followed development CKD. This prospective observational...
Introduction: Kidney allograft survival has increased significantly in the past few decades. However, more potent immunosuppression also resulted a higher incidence of infections including BK virus nephropathy (BKVN). The profile kidney transplant (KT) recipients age, basic disease, comorbidities, dialysis vintage, and type donor India is different from that high-income countries. There are very studies on outcomes BKVN India. We studied incidence, clinical features, impact screening...
Neural epidermal-like growth factor-like 1 (NELL-1) is a protein kinase C binding expressed in osteoblasts and renal tubules. It 5%-25% glomerular cells at the mRNA level. Membranous Nephropathy (MN) characterized by presence of antibodies against certain types antigens on basement membrane. The most common one implicated primary MN an antibody PLA2R. Many newer have been discovered recent past, which are proven to cause secondary MN, NELL-1. NELL-1 has associated with malignancy-associated...