Rachel Holstein
A5049995275- Influenza Virus Research Studies
- Respiratory viral infections research
- COVID-19 Clinical Research Studies
- COVID-19 and healthcare impacts
- Pneumonia and Respiratory Infections
- COVID-19 Impact on Reproduction
- Data-Driven Disease Surveillance
- Long-Term Effects of COVID-19
- Alcohol Consumption and Health Effects
- Suicide and Self-Harm Studies
- Gun Ownership and Violence Research
- Vaccine Coverage and Hesitancy
- Kawasaki Disease and Coronary Complications
- Sepsis Diagnosis and Treatment
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Animal Disease Management and Epidemiology
- Frailty in Older Adults
- Health disparities and outcomes
- Alcoholism and Thiamine Deficiency
- Neuroscience of respiration and sleep
- COVID-19 epidemiological studies
- Traumatic Ocular and Foreign Body Injuries
- Injury Epidemiology and Prevention
- Primary Care and Health Outcomes
National Center for Immunization and Respiratory Diseases
2021-2024
Centers for Disease Control and Prevention
2020-2024
Emory University
2023-2024
University School
2024
Government of the United States of America
2023
CDC Foundation
2019-2021
Oak Ridge Institute for Science and Education
2020
Oak Ridge Associated Universities
2020
Since SARS-CoV-2, the novel coronavirus that causes disease 2019 (COVID-19), was first detected in December (1), approximately 1.3 million cases have been reported worldwide (2), including 330,000 United States (3). To conduct population-based surveillance for laboratory-confirmed COVID-19-associated hospitalizations States, COVID-19-Associated Hospitalization Surveillance Network (COVID-NET) created using existing infrastructure of Influenza (FluSurv-NET) (4) and Respiratory Syncytial Virus...
Abstract Background Currently, the United States has largest number of reported coronavirus disease 2019 (COVID-19) cases and deaths globally. Using a geographically diverse surveillance network, we describe risk factors for severe outcomes among adults hospitalized with COVID-19. Methods We analyzed data from 2491 laboratory-confirmed COVID-19 between 1 March–2 May 2020, as identified through Coronavirus Disease 2019–Associated Hospitalization Surveillance Network, which comprises 154...
COVID-NET conducts population-based surveillance for laboratory-confirmed COVID-19-associated hospitalizations in 99 counties † 14 states (California, Connecticut, Colorado, Georgia, Iowa, Maryland, Michigan, Minnesota, New Mexico, York, Ohio, Oregon, Tennessee, and Utah), representing all 10 U.S. Department of Health Human Services regions (2,3).Laboratory-confirmed COVID-19associated among residents a predefined catchment area who had positive SARS-CoV-2 molecular test during...
Abstract Background Data on risk factors for coronavirus disease 2019 (COVID-19)–associated hospitalization are needed to guide prevention efforts and clinical care. We sought identify independently associated with COVID-19–associated hospitalizations. Methods Community-dwelling adults (aged ≥18 years) in the United States hospitalized laboratory-confirmed COVID-19 during 1 March–23 June 2020 were identified from COVID-19–Associated Hospitalization Surveillance Network (COVID-NET), a...
hospital admissions are subject to lag.
<h3>Importance</h3> Racial and ethnic minority groups, such as Black, Hispanic, American Indian or Alaska Native, Asian Pacific Islander persons, often experience higher rates of severe influenza disease. <h3>Objective</h3> To describe influenza-associated hospitalization, intensive care unit (ICU) admission, in-hospital death by race ethnicity over 10 seasons. <h3>Design, Setting, Participants</h3> This cross-sectional study used data from the Influenza-Associated Hospitalization...
Influenza burden varies across seasons, partly due to differences in circulating influenza virus types or subtypes. Using data from the US population-based surveillance system, Hospitalization Surveillance Network (FluSurv-NET), we aimed assess severity of influenza-associated outcomes individuals hospitalised with laboratory-confirmed infections during 2010-11 2018-19 seasons.
Abstract Background Influenza virus and SARS-CoV-2 are significant causes of respiratory illness in children. Methods Influenza- COVID-19–associated hospitalizations among children &lt;18 years old were analyzed from FluSurv-NET COVID-NET, 2 population-based surveillance systems with similar catchment areas methodology. The annual hospitalization rate per 100 000 during the ongoing COVID-19 pandemic (1 October 2020–30 September 2021) was compared influenza-associated rates 2017–2018...
CDC estimates that influenza resulted in 9-41 million illnesses, 140,000-710,000 hospitalizations, and 12,000-52,000 deaths annually during 2010-2020. Persons from some racial ethnic minority groups have historically experienced higher rates of severe had lower vaccination coverage compared with non-Hispanic White (White) persons. This report examines hospitalization by race ethnicity a 12-13-year period (through the 2021-22 season).Data population-based surveillance for laboratory-confirmed...
Pneumonia is common in adults hospitalized with laboratory-confirmed influenza, but the association between timeliness of influenza antiviral treatment and severe clinical outcomes patients influenza-associated pneumonia not well characterized.
Background: As of May 15, 2020, the United States has reported greatest number coronavirus disease 2019 (COVID-19) cases and deaths globally. Objective: To describe risk factors for severe outcomes among adults hospitalized with COVID-19. Design: Cohort study patients identified through Coronavirus Disease 2019-Associated Hospitalization Surveillance Network. Setting: 154 acute care hospitals in 74 counties 13 states. Patients: 2491 laboratory-confirmed COVID-19 during March 1-May 2, 2020....
Pregnant women may be at increased risk for severe influenza-associated outcomes.To describe characteristics and outcomes of hospitalized pregnant with influenza.Repeated cross-sectional study.The population-based U.S. Influenza Hospitalization Surveillance Network during the 2010-2011 through 2018-2019 influenza seasons.Pregnant (aged 15 to 44 years) laboratory-confirmed identified provider-initiated or facility-based testing practices.Clinical characteristics, interventions, in-hospital...
Abstract Among 513 adults aged 18–49 years without underlying medical conditions hospitalized with coronavirus disease 2019 (COVID-19) during March 2020–August 2020, 22% were admitted to an intensive care unit, 10% required mechanical ventilation, and 3 patients died (0.6%). These data demonstrate that healthy younger can develop severe COVID-19.
Objectives Some studies suggested more COVID-19-associated hospitalizations among racial and ethnic minorities. To inform public health practice, the Hospitalization Surveillance Network (COVID-NET) quantified associations between race/ethnicity, census tract socioeconomic indicators, hospitalization rates. Methods Using data from COVID-NET population-based surveillance reported during March 1–April 30, 2020 along with denominator US Census Bureau, we calculated rates by racial/ethnic...
Abstract Background While the estimated number of US influenza-associated deaths is reported annually, detailed data on epidemiology deaths, including burden in-hospital vs post-hospital discharge are limited. Methods Using from 2010–2011 through 2018–2019 seasons Influenza Hospitalization Surveillance Network, we linked cases to death certificates identify patients who died any cause during their influenza hospital stay or within 30 days post discharge. We described demographic and clinical...
Background Firearm-related injury (FRI) became the leading cause of death among children/adolescents in 2019. Purpose This study sought to determine changes over time population adolescents affected by FRI Atlanta, Georgia, such that high risk cohorts could be identified. Research Design City-wide retrospective cohort review. Study Sample Adolescent victims (age 11-21 years age) FRI, defined ICD9/10 codes, Georgia. Data Analysis Descriptive, multivariate and series analysis. Results There...
Abstract Background Influenza virus and SARS-CoV-2 are significant causes of respiratory illness in children. Methods COVID-19-associated hospitalizations among children <18 years old were analyzed from FluSurv-NET COVID-NET, two population-based surveillance systems with similar catchment areas methodology. The annual hospitalization rate per 100 000 during the ongoing COVID-19 pandemic (October 1, 2020–September 30, 2021) was compared to influenza-associated rates 2017–18 through...
Influenza is a persistent public health problem associated with severe morbidity and mortality. Drug use related to myriad complications, but the relationship between drug influenza outcomes not well understood. The study objective was evaluate influenza-associated outcomes.Data were collected by Hospitalization Surveillance Network (FluSurv-NET) from 2016-2017 through 2018-2019 seasons. Among persons hospitalized influenza, descriptive statistics logistic regression models used analyze...
Introduction: Influenza burden varies across seasons, due in part to differences circulating influenza virus types/subtypes. Using the U.S. Hospitalization Surveillance Network (FluSurv-NET), we assessed severity of influenza-associated outcomes among individuals hospitalized with A(H3N2), A(H1N1)pdm09, and B infections during 2010─11 through 2018─19 seasons.Methods: To evaluate association between type/subtype in-hospital severe (intensive care unit [ICU] admission, mechanical ventilation...
Abstract Background The 2018–19 influenza season was characterized by prolonged co-circulation of Influenza A H3N2 (H3) and H1N1pdm09 (H1) viruses. We used data from the Hospitalization Surveillance Network (FluSurv-NET) to describe age-related differences in distribution subtypes. Methods included all cases residing within a FluSurv-NET catchment area hospitalized with laboratory-confirmed during October 1, 2018–April 30, 2019. multiply imputed subtype for 63% unknown based imputation on...
Abstract Background Pregnant women are at high-risk for influenza-associated hospitalization. We used data from the U.S. Influenza Hospitalization Surveillance Network (FluSurv-NET) to characterize pregnant hospitalized with influenza. Methods included (15–44 years) residing within a FluSurv-NET catchment area and laboratory-confirmed influenza between October 1 April 30, during 2010–19 seasons. Clinical were obtained on cases through medical chart abstraction. examined trends in vaccination...
Background: Influenza is a persistent public health problem associated with severe morbidity and mortality. Drug use related to myriad complications, but the relationship between drug influenza outcomes not well understood. The study objective was evaluate influenza-associated outcomes. Methods: Data were collected by Hospitalization Surveillance Network (FluSurv-NET) from 2016-2017 through 2018-2019 seasons. Among persons hospitalized influenza, descriptive statistics logistic regression...