Uzair Jafar

ORCID: 0000-0003-0737-7444
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About
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Research Areas
  • COVID-19 Clinical Research Studies
  • Liver Disease and Transplantation
  • Cardiovascular Function and Risk Factors
  • Liver Disease Diagnosis and Treatment
  • Diabetes Treatment and Management
  • Heart Failure Treatment and Management
  • SARS-CoV-2 and COVID-19 Research
  • Viral Infections and Vectors
  • Allergic Rhinitis and Sensitization
  • Pharmaceutical industry and healthcare
  • Academic Publishing and Open Access
  • Heparin-Induced Thrombocytopenia and Thrombosis
  • Viral Infections and Outbreaks Research
  • Cardiovascular Issues in Pregnancy
  • Hyperglycemia and glycemic control in critically ill and hospitalized patients
  • Preterm Birth and Chorioamnionitis
  • Infant Development and Preterm Care
  • Psoriasis: Treatment and Pathogenesis
  • Pharmacological Receptor Mechanisms and Effects
  • Rheumatoid Arthritis Research and Therapies
  • Venous Thromboembolism Diagnosis and Management
  • Cardiac pacing and defibrillation studies
  • Cancer therapeutics and mechanisms
  • Advanced biosensing and bioanalysis techniques
  • Inflammasome and immune disorders

King Edward Medical University
2022-2025

The majority of available data on molnupiravir come from an unvaccinated COVID-19 population. Therefore, we conducted this meta-analysis to integrate evidence recent randomized controlled trials (RCTs) as well observational studies stratified by vaccination status determine the clinical efficacy and safety in outpatients.

10.1016/j.jmii.2024.03.002 article EN cc-by Journal of Microbiology Immunology and Infection 2024-03-16

Abstract Background Soluble guanylate cyclase (sGC) stimulators have been investigated for heart failure (HF) in several randomized controlled trials (RCTs). However, its place the management guidelines of either HFrEF or HfpEF is still inconclusive. Methods We conducted a network meta-analysis synthesizing RCTs investigating sGC HF management, which were retrieved by systematically searching five databases until January 24th, 2023. Dichotomous outcomes pooled using risk ratio (RR) along...

10.1186/s43044-024-00437-x article EN cc-by The Egyptian Heart Journal 2024-01-24

Abstract Background Heart failure (HF), either with reduced ejection fraction (HFrEF) or preserved (HFpEF), is a significant healthcare burden, about one million hospitalizations annually in the United States alone. Soluble guanylate cyclase (sGC) stimulators have been investigated for HF treatment several randomized controlled trials (RCTs). However, its place management guidelines of HFrEF HfpEF still inconclusive. Purpose We aim to evaluate efficacy and safety sGC determine most effective...

10.1093/eurheartj/ehad655.969 article EN European Heart Journal 2023-11-01

Introduction: One of the several complications associated with preterm birth is bronchopulmonary dysplasia (BPD), a disorder characterized by abnormal development lungs and subsequent breathing problems. We aim to determine safety efficacy late (≥ 7 days) systemic corticosteroids for prevention BPD in infants. Methods: searched electronic databases, international trial registers, grey literature sources, reference lists articles identify relevant randomized controlled trials (RCTs) on use...

10.1097/01.ccm.0000909592.11809.6d article EN Critical Care Medicine 2022-12-15
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