A5049222816- Acute Myeloid Leukemia Research
- Chronic Lymphocytic Leukemia Research
- Hematological disorders and diagnostics
- Lymphoma Diagnosis and Treatment
- Hematopoietic Stem Cell Transplantation
- AI in cancer detection
- Genomics and Chromatin Dynamics
- Veterinary Oncology Research
- Radiomics and Machine Learning in Medical Imaging
- Nonmelanoma Skin Cancer Studies
- Acute Lymphoblastic Leukemia research
- Sarcoma Diagnosis and Treatment
- Multiple Myeloma Research and Treatments
- Cardiac Imaging and Diagnostics
- Molecular Biology Techniques and Applications
- Thyroid Cancer Diagnosis and Treatment
- Myeloproliferative Neoplasms: Diagnosis and Treatment
- Oral and Maxillofacial Pathology
- Gene expression and cancer classification
- Bone Tumor Diagnosis and Treatments
- Fractal and DNA sequence analysis
- Chronic Myeloid Leukemia Treatments
- Cancer and Skin Lesions
- Immunodeficiency and Autoimmune Disorders
- Vascular Tumors and Angiosarcomas
Universidade Estadual de Campinas (UNICAMP)
2015-2024
Massachusetts General Hospital
2020
The University of Texas MD Anderson Cancer Center
2020
Università Cattolica del Sacro Cuore
2020
Charles River Laboratories (Netherlands)
2020
John Wiley & Sons (United States)
2020
Malama Learning Center
2015
Universidade Federal do Piauí
2015
University of Würzburg
2011
Hospital de Clínicas da Unicamp
2006-2010
Aims : To investigate the usefulness of immunohistochemical expression and immunolocalization a panel thyroid malignancy markers including HBME‐1, cytokeratin (CK) 19 galectin‐3. Methods results We evaluated 170 lesions 148 neoplastic [84 papillary carcinomas (PC), 38 follicular (FC), 18 adenomas, one hyalinizing trabecular tumour, five medullary carcinomas, two anaplastic carcinomas] 22 non‐neoplastic (12 adenomatous nodules 10 Hashimoto's thyroiditis). galectin‐3 CK19 were expressed in...
Prognostic factors in malignant melanoma are currently based on clinical data and morphologic examination. Other prognostic features, however, which not yet used daily practice, might add important information thus improve prognosis, treatment, survival. Therefore a search for new markers is desirable. Previous studies have demonstrated that fractal characteristics of nuclear chromatin importance neoplasias. We therefore investigated whether the dimension measured routine histological...
Abstract Introduction Lichenoid drug eruption (LDE) shares similar features with lichen planus (LP), that could reflect the same pathogenesis. In LP, an autoimmune attack is accepted and cytotoxic T‐lymphocytes (CD8+) predominate, especially in late lesions. Apoptosis of keratinocytes may be mediated by CD8+ T NK cells two distinct ways: release molecules such as perforin granzyme B or Fas/FasL system. The immunological mechanisms involved LDE are not yet fully established. Objectives...
The fractal nature of the DNA arrangement has been postulated to be a common feature all cell nuclei. We investigated prognostic importance dimension (FD) chromatin in blasts patients with acute precursor B lymphoblastic leukemia (B‐ALL). In 28 patients, gray scale transformed pseudo‐3D images 100 nuclei (May–Grünwald–Giemsa stained bone marrow smears) were analyzed. FD was determined by Minkowski–Bouligand method extended three dimensions. Goodness‐of‐fit estimated R2 values log‐log plots....
Abstract Background Children born to HIV+ mothers are exposed intra-utero several drugs and cytokines that can modify the developing immune system, influence newborn's response infections vaccines. We analyzed relation between distribution of cord blood lymphocyte subsets cytokine profile in term newborns using HAART during pregnancy compared them normal newborns. Methods In a prospective, controlled study, 36 mother-child pairs from 15 HIV-uninfected were studied. Hematological features...
Background The use of computerized image analysis for the study nuclear texture features has provided important prognostic information several neoplasias. Recently fractal characteristics chromatin structure in routinely stained smears have shown to be independent factors acute leukemia. In present we investigated influence dimension (FD) on survival patients with multiple myeloma. Methodology We analyzed 67 newly diagnosed from our Institution treated Brazilian Multiple Myeloma Study Group....
Abstract Background Immunohistochemical studies of lymphatic vessels have been limited by a lack specific markers. Recently, the novel D2-40 antibody, which selectively marks endothelium vessels, was released. The aim our study is to compare and blood vessel invasion detected hematoxylin eosin (H&E) versus that immunohistochemistry, relating them with morphologic molecular prognostic factors. Methods We selected 123 cases invasive mammary carcinomas stratified into three subgroups...
Differences in age and sex distribution as well FAB (French-American-British classification) types have been reported for acute leukemias several countries. We studied the demographics response to treatment of patients with myeloid leukemia (AML) lymphoblastic (ALL) between 1989 2000 Teresina, Piauí, compared these results reports from Brazil other Complete data concerning 345 (230 ALL, 115 AML) were reviewed. AML occurred predominantly adults (77%), a median 34 years, similar that found...